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Hong Yu 虞
Hong Yu 虞
Senior Scientist, Janssen
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins
AS Kato, MB Gill, MT Ho, H Yu, Y Tu, ER Siuda, H Wang, YW Qian, ...
Neuron 68 (6), 1082-1096, 2010
1942010
New transmembrane AMPA receptor regulatory protein isoform, γ-7, differentially regulates AMPA receptors
AS Kato, W Zhou, AD Milstein, MD Knierman, ER Siuda, JE Dotzlaf, H Yu, ...
Journal of Neuroscience 27 (18), 4969-4977, 2007
1802007
TARPs differentially decorate AMPA receptors to specify neuropharmacology
AS Kato, MB Gill, H Yu, ES Nisenbaum, DS Bredt
Trends in neurosciences 33 (5), 241-248, 2010
1752010
Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas
KW Perry, JF Falcone, MJ Fell, JW Ryder, H Yu, PL Love, J Katner, ...
Neuropharmacology 55 (5), 743-754, 2008
1002008
Cornichon-2 modulates AMPA receptor–transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology
MB Gill, AS Kato, MF Roberts, H Yu, H Wang, S Tomita, DS Bredt
Journal of Neuroscience 31 (18), 6928-6938, 2011
942011
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism
AS Kato, KD Burris, KM Gardinier, DL Gernert, WJ Porter, J Reel, C Ding, ...
Nature medicine 22 (12), 1496-1501, 2016
832016
Germline RET mutations in MEN 2A and FMTC and their detection by simple DNA diagnostic tests
F Xue, H Yu, LH Maurer, VA Memoll, N Nutile-McMenemy, MK Schuster, ...
Human molecular genetics 3 (4), 635-638, 1994
661994
Discovery of the first α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist dependent upon transmembrane AMPA receptor regulatory protein (TARP) γ-8
KM Gardinier, DL Gernert, WJ Porter, JK Reel, PL Ornstein, P Spinazze, ...
Journal of medicinal chemistry 59 (10), 4753-4768, 2016
572016
Porcupine controls hippocampal AMPAR levels, composition, and synaptic transmission
N Erlenhardt, H Yu, K Abiraman, T Yamasaki, JI Wadiche, S Tomita, ...
Cell reports 14 (4), 782-794, 2016
482016
[3 H] N-2-(4-(N-benzamido) phenyl) propyl-2-propanesulfonamide: a novel AMPA receptor potentiator and radioligand
H Zarrinmayeh, D Bleakman, MR Gates, H Yu, DM Zimmerman, ...
Journal of medicinal chemistry 3 (44), 302-304, 2001
322001
Possible involvement of the lysine ε-aminotransferase gene (lat) in the expression of the genes encoding ACV synthetase (pcbAB) and isopenicillin N synthase (pcbC) in …
H Yu, E Serpe, J Romero, JJ Coque, K Maeda, M Oelgeschläger, ...
Microbiology 140 (12), 3367-3377, 1994
321994
α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins
GB Dawe, H Yu, S Gu, AN Blackler, JA Matta, ER Siuda, EB Rex, ...
Nature Communications 10 (1), 2746, 2019
302019
Binding of an AMPA receptor potentiator ([3H] LY395153) to native and recombinant AMPA receptors
AM Lindén, H Yu, H Zarrinmayeh, WJ Wheeler, P Skolnick
Neuropharmacology 40 (8), 1010-1018, 2001
292001
Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators
DA Schober, MB Gill, H Yu, DL Gernert, MW Jeffries, PL Ornstein, AS Kato, ...
Journal of Biological Chemistry 286 (15), 13134-13142, 2011
242011
Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology
M Dhara, JA Matta, M Lei, D Knowland, H Yu, S Gu, DS Bredt
Nature Communications 11 (1), 2799, 2020
232020
NACHO engages N-glycosylation ER chaperone pathways for α7 nicotinic receptor assembly
HJ Kweon, S Gu, E Witham, M Dhara, H Yu, ED Mandon, A Jawhari, ...
Cell reports 32 (6), 2020
162020
AMPA receptor function is altered in GLUR2-deficient mice
SC Harvey, A Köster, H Yu, P Skolnick, P Baumbarger, ES Nisenbaum
Journal of Molecular Neuroscience 17, 35-43, 2001
162001
In Vivo Characterization of Changes in Glycine Levels Induced by GlyT1 Inhibitors
KW Johnson, AMY CLEMENS‐SMITH, G Nomikos, R Davis, L Phebus, ...
Annals of the New York Academy of Sciences 1003 (1), 412-414, 2003
152003
Discovery and SAR studies of novel GlyT1 inhibitors
MW Walter, BJ Hoffman, K Gordon, K Johnson, P Love, M Jones, T Man, ...
Bioorganic & medicinal chemistry letters 17 (18), 5233-5238, 2007
132007
A single residue contributes sensitivity to allosteric modulation of AMPA receptors by LY395153
JC Quirk, AM Linden, M Strakhova, H Yu, P Skolnick, ES Nisenbaum
European journal of pharmacology 454 (2-3), 125-129, 2002
62002
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