| A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells DM Mellott, CT Tseng, A Drelich, P Fajtová, BC Chenna, DH Kostomiris, ... ACS chemical biology 16 (4), 642-650, 2021 | 94 | 2021 |
| Biosynthesis of Taxadiene in Saccharomyces cerevisiae : Selection of Geranylgeranyl Diphosphate Synthase Directed by a Computer-Aided Docking Strategy M Ding, H Yan, L Li, F Zhai, L Shang, Z Yin, Y Yuan PloS one 9 (10), e109348, 2014 | 77 | 2014 |
| Anti‐dengue‐virus activity and structure–activity relationship studies of lycorine derivatives P Wang, LF Li, QY Wang, LQ Shang, PY Shi, Z Yin ChemMedChem 9 (7), 1522-1533, 2014 | 77 | 2014 |
| Cyanohydrin as an anchoring group for potent and selective inhibitors of enterovirus 71 3C protease Y Zhai, X Zhao, Z Cui, M Wang, Y Wang, L Li, Q Sun, X Yang, D Zeng, ... Journal of medicinal chemistry 58 (23), 9414-9420, 2015 | 65 | 2015 |
| Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L AS Ashhurst, AH Tang, P Fajtová, MC Yoon, A Aggarwal, MJ Bedding, ... Journal of Medicinal Chemistry, 2021 | 48 | 2021 |
| Structure‐guided Discovery of a Novel Non‐peptide Inhibitor of Dengue Virus NS2B–NS3 Protease L Li, C Basavannacharya, KWK Chan, L Shang, SG Vasudevan, Z Yin Chemical biology & drug design 86 (3), 255-264, 2015 | 42 | 2015 |
| Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review J Zheng, W Zhang, L Li, Y He, Y Wei, Y Dang, S Nie, Z Guo Frontiers in Chemistry 10, 2022 | 35 | 2022 |
| Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases L Li, BC Chenna, KS Yang, TR Cole, ZT Goodall, M Giardini, ... Journal of Medicinal Chemistry 64 (15), 11267-11287, 2021 | 26 | 2021 |
| Application of dually activated michael acceptor to the rational design of reversible covalent inhibitor for enterovirus 71 3C protease Y Ma, L Li, S He, C Shang, Y Sun, N Liu, TD Meek, Y Wang, L Shang Journal of medicinal chemistry 62 (13), 6146-6162, 2019 | 25 | 2019 |
| 4-Iminooxazolidin-2-one as a Bioisostere of the cyanohydrin moiety: inhibitors of Enterovirus 71 3C protease Y Ma, C Shang, P Yang, L Li, Y Zhai, Z Yin, B Wang, L Shang Journal of medicinal chemistry 61 (22), 10333-10339, 2018 | 24 | 2018 |
| Biochemical characterization of recombinant enterovirus 71 3C protease with fluorogenic model peptide substrates and development of a biochemical assay L Shang, S Zhang, X Yang, J Sun, L Li, Z Cui, Q He, Y Guo, Y Sun, Z Yin Antimicrobial agents and chemotherapy 59 (4), 1827-1836, 2015 | 24 | 2015 |
| Peptidomimetic vinyl heterocyclic inhibitors of cruzain effect antitrypanosomal activity BC Chenna, L Li, DM Mellott, X Zhai, JL Siqueira-Neto, C Calvet Alvarez, ... Journal of medicinal chemistry 63 (6), 3298-3316, 2020 | 23 | 2020 |
| Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L A Ashhurst, A Tang, P Fajtová, M Yoon, A Aggarwal, A Stoye, M Larance, ... bioRxiv, 2020 | 11 | 2020 |
| Enzymatic synthesis of a 6-sialyl lactose analogue using a pH-responsive water-soluble polymer support W Wang, L Li, C Jin, Y Niu, S Li, J Ma, L Li, Y Liu, L Cai, W Zhao, ... Bioorganic & medicinal chemistry letters 21 (17), 5041-5044, 2011 | 9 | 2011 |
| A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells DM Mellott, CT Tseng, A Drelich, P Fajtová, BC Chenna, DH Kostomiris, ... bioRxiv, 2020 | | 2020 |
Thomas D. MeekProfessor of Biochemistry & Biophysics, Texas A&M UniversityVerified email at tamu.edu
