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John R White
John R White
Verified email at gsk.com
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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
JC Lee, JT Laydon, PC McDonnell, TF Gallagher, S Kumar, D Green, ...
Nature 372 (6508), 739-746, 1994
41421994
Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration
JR White, JM Lee, PR Young, RP Hertzberg, AJ Jurewicz, MA Chaikin, ...
Journal of Biological Chemistry 273 (17), 10095-10098, 1998
5351998
Glycan array screening reveals a candidate ligand for Siglec-8
BS Bochner, RA Alvarez, P Mehta, NV Bovin, O Blixt, JR White, ...
Journal of Biological Chemistry 280 (6), 4307-4312, 2005
3112005
The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD 2, PGE 1, forskolin)
MB Feinstein, JJ Egan, RI Sha'Afi, J White
Biochemical and biophysical research communications 113 (2), 598-604, 1983
2651983
Phorbol 12-myristate 13-acetate activates rabbit neutrophils without an apparent rise in the level of intracellular free calcium
RI Sha'Afi, JR White, TFP Molski, J Shefcyk, M Volpi, PH Naccache, ...
Biochemical and biophysical research communications 114 (2), 638-645, 1983
2631983
Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12, 13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.
JR White, CK Huang, JM Hill, PH Naccache, EL Becker, RI Sha'Afi
Journal of Biological Chemistry 259 (13), 8605-8611, 1984
2491984
Differential chemotactic behavior of developing T cells in response to thymic chemokines
CH Kim, LM Pelus, JR White, HE Broxmeyer
Blood, The Journal of the American Society of Hematology 91 (12), 4434-4443, 1998
2481998
Phorbol esters inhibit the fMet-Leu-Phe-and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.
PH Naccache, TF Molski, P Borgeat, JR White, RI Sha'Afi
Journal of Biological Chemistry 260 (4), 2125-2131, 1985
2261985
Production of the novel CC chemokine MCP-4 by airway cells and comparison of its biological activity to other CC chemokines.
C Stellato, P Collins, PD Ponath, D Soler, W Newman, G La Rosa, H Li, ...
The Journal of clinical investigation 99 (5), 926-936, 1997
2211997
Direct demonstration of increased intracellular concentration of free calcium in rabbit and human neutrophils following stimulation by chemotactic factor
JR White, PH Naccache, TFP Molski, P Borgeat, RI Sha'Afi
Biochemical and biophysical research communications 113 (1), 44-50, 1983
2171983
Determination of the monomer-dimer equilibrium of interleukin-8 reveals it is a monomer at physiological concentrations
SD Burrows, ML Doyle, KP Murphy, SG Franklin, JR White, I Brooks, ...
Biochemistry 33 (43), 12741-12745, 1994
2121994
Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils.
JR White, C Imburgia, E Dul, E Appelbaum, K O'donnell, DJ O'Shannessy, ...
Journal of leukocyte biology 62 (5), 667-675, 1997
2071997
A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit
PL Podolin, BJ Bolognese, JJ Foley, DB Schmidt, PT Buckley, ...
The Journal of Immunology 169 (11), 6435-6444, 2002
1982002
Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors
JC Lee, AM Badger, DE Griswold, D Dunnington, A Truneh, B Votta, ...
Annals of the New York Academy of Sciences 696 (1), 149-170, 1993
1901993
Stimulation by chemotactic factor of actin association with the cytoskeleton in rabbit neutrophils. Effects of calcium and cytochalasin B.
JR White, PH Naccache, RI Sha'Afi
Journal of Biological Chemistry 258 (22), 14041-14047, 1983
1851983
Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils
KK Kikly, BS Bochner, SD Freeman, KB Tan, KT Gallagher, KJ D’Alessio, ...
Journal of allergy and clinical immunology 105 (6), 1093-1100, 2000
1822000
Direct demonstration of increased intracellular concentration of free calcium as measured by quin-2 in stimulated rat peritoneal mast cell
JR White, T Ishizaka, K Ishizaka, R Sha'afi
Proceedings of the National Academy of Sciences 81 (13), 3978-3982, 1984
1741984
Imidazole derivatives and their use as cytokine inhibitors
JL Adams, TF Gallagher, JC Lee, JR White
US Patent 5,686,455, 1997
1731997
Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast.
TJ Torphy, JM Stadel, M Burman, LB Cieslinski, MM McLaughlin, ...
Journal of Biological Chemistry 267 (3), 1798-1804, 1992
1691992
Differential regulation of epithelial-derived CC chemokine expression by IL-4 and the glucocorticoid budesonide
C Stellato, S Matsukura, A Fal, J White, LA Beck, D Proud, RP Schleimer
The Journal of Immunology 163 (10), 5624-5632, 1999
1541999
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