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S J Broughton
S J Broughton
Verified email at lancaster.ac.uk
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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
SJ Broughton, MDW Piper, T Ikeya, TM Bass, J Jacobson, Y Driege, ...
Proceedings of the National Academy of Sciences 102 (8), 3105-3110, 2005
9532005
Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides
S Grönke, DF Clarke, S Broughton, TD Andrews, L Partridge
PLoS genetics 6 (2), e1000857, 2010
6922010
Insulin/IGF-like signalling, the central nervous system and aging
S Broughton, L Partridge
Biochemical Journal 418 (1), 1-12, 2009
2822009
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs
S Broughton, N Alic, C Slack, T Bass, T Ikeya, G Vinti, AM Tommasi, ...
PloS one 3 (11), e3721, 2008
2272008
The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila
T Ikeya, S Broughton, N Alic, R Grandison, L Partridge
Proceedings of the Royal Society B: Biological Sciences 276 (1674), 3799-3807, 2009
1622009
DILP‐producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition
SJ Broughton, C Slack, N Alic, A Metaxakis, TM Bass, Y Driege, ...
Aging cell 9 (3), 336-346, 2010
1422010
Excitatory and inhibitory switches for courtship in the brain of Drosophila melanogaster
SJ Broughton, T Kitamoto, RJ Greenspan
Current Biology 14 (7), 538-547, 2004
842004
Cell-nonautonomous effects of dFOXO/DAF-16 in aging
N Alic, JM Tullet, T Niccoli, S Broughton, MP Hoddinott, C Slack, D Gems, ...
Cell reports 6 (4), 608-616, 2014
632014
The Drosophila insulin receptor independently modulates lifespan and locomotor senescence
MZBH Ismail, MD Hodges, M Boylan, R Achall, A Shirras, SJ Broughton
PLoS One 10 (5), e0125312, 2015
402015
Endogenously inhibited protein kinase C in transgenic Drosophila embryonic neuroblasts down regulates the outgrowth of type I and II processes of cultured mature neurons
SJ Broughton, NS Kane, B Arthur, M Yoder, RJ Greenspan, A Robichon
Journal of cellular biochemistry 60 (4), 584-599, 1996
291996
Partial inhibition of RNA polymerase I promotes animal health and longevity
GM Corrales, D Filer, KC Wenz, A Rogan, G Phillips, M Li, Y Feseha, ...
Cell reports 30 (6), 1661-1669. e4, 2020
262020
Behavioral senescence and aging-related changes in motor neurons and brain neuromodulator levels are ameliorated by lifespan-extending reproductive dormancy in Drosophila
S Liao, S Broughton, DR Nässel
Frontiers in cellular neuroscience 11, 111, 2017
252017
Conditioning deficits of CaM-kinase transgenic Drosophila melanogaster in a new excitatory courtship assay
SJ Broughton, T Tully, RJ Greenspan
Journal of neurogenetics 17 (1), 91-102, 2003
202003
Ketamine restores thalamic-prefrontal cortex functional connectivity in a mouse model of neurodevelopmental disorder-associated 2p16. 3 deletion
R B Hughes, J Whittingham-Dowd, RE Simmons, SJ Clapcote, ...
Cerebral Cortex 30 (4), 2358-2371, 2020
152020
Loss of angiotensin-converting enzyme-related (ACER) peptidase disrupts behavioural and metabolic responses to diet in Drosophila melanogaster
Z Glover, MD Hodges, N Dravecz, J Cameron, H Askwith, A Shirras, ...
Journal of Experimental Biology 222 (8), jeb194332, 2019
112019
Microbes, molecular mimicry and molecules of mood and motivation
JA Morris, SJ Broughton, Q Wessels
Medical Hypotheses 87, 40-43, 2016
102016
Transport of CaM kinase along processes elicited by neuronal contact evokes an inhibition of arborization and outgrowth in D. melanogaster cultured neurons
SJ Broughton, NS Kane, M Yoder, RJ Greenspan, A Robichon
Journal of cellular biochemistry 62 (4), 484-494, 1996
101996
Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behavior in a mouse model of autism‐associated 2p16. 3 deletion
RB Hughes, J Whittingham‐Dowd, SJ Clapcote, SJ Broughton, N Dawson
Autism Research 15 (4), 614-627, 2022
92022
Differential regulation of E-cadherin expression by the soluble ectodomain and intracellular domain of Jagged1
C Delury, C Tinker, S Rivers, M Hodges, S Broughton, E Parkin
International Journal of Biochemistry Research & Review 3 (4), 278-290, 2013
42013
Response to thermal and infection stresses in an American vector of visceral leishmaniasis
KA Martins, CS Morais, SJ Broughton, CR Lazzari, PA Bates, MH Pereira, ...
Medical and Veterinary Entomology 37 (2), 238-251, 2023
22023
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