| Base editing of haematopoietic stem cells rescues sickle cell disease in mice GA Newby, JS Yen, KJ Woodard, T Mayuranathan, CR Lazzarotto, Y Li, ... Nature 595 (7866), 295-302, 2021 | 233 | 2021 |
| Genome editing of HBG1 and HBG2 to induce fetal hemoglobin JY Métais, PA Doerfler, T Mayuranathan, DE Bauer, SC Fowler, MM Hsieh, ... Blood advances 3 (21), 3379-3392, 2019 | 138 | 2019 |
| ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression X Lan, R Ren, R Feng, LC Ly, Y Lan, Z Zhang, N Aboreden, K Qin, ... Molecular cell 81 (2), 239-254. e8, 2021 | 57 | 2021 |
| Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice KA Everette, GA Newby, RM Levine, K Mayberry, Y Jang, T Mayuranathan, ... Nature biomedical engineering 7 (5), 616-628, 2023 | 40 | 2023 |
| Transforming growth factor‐β1 regulation of ATF‐3 and identification of ATF‐3 target genes in breast cancer cells S Kwok, SR Rittling, NC Partridge, CS Benson, M Thiyagaraj, ... Journal of cellular biochemistry 108 (2), 408-414, 2009 | 38 | 2009 |
| Activation of γ-globin expression by hypoxia-inducible factor 1α R Feng, T Mayuranathan, P Huang, PA Doerfler, Y Li, Y Yao, J Zhang, ... Nature 610 (7933), 783-790, 2022 | 18 | 2022 |
| Potent and uniform fetal hemoglobin induction via base editing T Mayuranathan, GA Newby, R Feng, Y Yao, KD Mayberry, CR Lazzarotto, ... Nature genetics 55 (7), 1210-1220, 2023 | 17 | 2023 |
| Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells K Qin, P Huang, R Feng, CA Keller, SA Peslak, E Khandros, MS Saari, ... Nature genetics 54 (6), 874-884, 2022 | 17 | 2022 |
| Identification of rare and novel deletions that cause (δβ)0‐thalassaemia and hereditary persistence of foetal haemoglobin in Indian population T Mayuranathan, J Rayabaram, R Das, N Arora, ES Edison, M Chandy, ... European Journal of Haematology 92 (6), 514-520, 2014 | 16 | 2014 |
| Adenosine base editing of γ-globin promoters induces fetal hemoglobin and inhibit erythroid sickling T Mayuranathan, JS Yen, GA Newby, Y Yao, SN Porter, KJ Woodard, ... Blood 136, 21-22, 2020 | 8 | 2020 |
| Genome editing of HBG1 and HBG2 to induce fetal hemoglobin. Blood Adv 3: 3379–3392 JY Métais, PA Doerfler, T Mayuranathan, DE Bauer, SC Fowler, MM Hsieh, ... | 7 | 2019 |
| A novel deletion of β-globin promoter causing high HbA2 in an Indian population T Mayuranathan, J Rayabaram, ES Edison, A Srivastava, SR Velayudhan haematologica 97 (9), 1445, 2012 | 7 | 2012 |
| An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity SV Bhoopalan, JS Yen, T Mayuranathan, KD Mayberry, Y Yao, ... JCI insight 8 (1), 2023 | 5 | 2023 |
| Base editing eliminates the sickle cell mutation and pathology in hematopoietic stem cells derived erythroid cells JS Yen, GA Newby, T Mayuranathan, SN Porter, Y Yao, KJ Woodard, ... Blood 136, 13-14, 2020 | 5 | 2020 |
| Regulation of fetal hemoglobin expression by the VHL-HIF1α oxygen sensing system R Feng, T Mayuranathan, P Huang, PA Doerfler, Y Li, Y Yao, J Zhang, ... Blood 138, 574, 2021 | 4 | 2021 |
| A novel RPS19-edited hematopoietic stem cell model of Diamond-Blackfan anemia for development of lentiviral vector gene therapy SV Bhoopalan, J Yen, T Mayuranathan, Y Yao, K Mayberry, S Zhou, ... Blood 138, 859, 2021 | 4 | 2021 |
| Identification of Erythroid Specific Enhancers By Analyzing Genome Wide Association of Transcriptional Co-Activators CBP and P300 T Mayuranathan, J Rayabaram, A Nath, SR Velayudhan Blood 126 (23), 3330, 2015 | 2 | 2015 |
| Multiplex Base Editing to Protect from CD33-Directed Therapy: Implications for Immune and Gene Therapy F Borot, O Humbert, GA Newby, E Fields, S Kohli, S Radtke, GS Laszlo, ... bioRxiv, 2023.02. 23.529353, 2023 | 1 | 2023 |
| CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies JY Metais, PA Doerfler, T Mayuranathan, DE Bauer, S Fowler, M Hsieh, ... Blood 134, 2066, 2019 | 1 | 2019 |
| Ancestral β-globin gene haplotypes modify β-thalassemia severity in a mouse model C Lechauve, J Keith, AG Fernandez, E Khandros, K Mayberry, ... Blood Advances, 2024 | | 2024 |
