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Matthew Simon
Matthew Simon
Study Director, The Jackson Laboratory
Verified email at jax.org
Title
Cited by
Cited by
Year
L1 drives IFN in senescent cells and promotes age-associated inflammation
M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ...
Nature 566 (7742), 73-78, 2019
8112019
LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation
M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ...
Cell metabolism 29 (4), 871-885. e5, 2019
3462019
SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species
X Tian, D Firsanov, Z Zhang, Y Cheng, L Luo, G Tombline, R Tan, ...
Cell 177 (3), 622-638. e22, 2019
2472019
JNK phosphorylates SIRT6 to stimulate DNA double-strand break repair in response to oxidative stress by recruiting PARP1 to DNA breaks
M Van Meter, M Simon, G Tombline, A May, TD Morello, BP Hubbard, ...
Cell reports 16 (10), 2641-2650, 2016
1342016
Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants
M Simon, P Sarkies, K Ikegami, AL Doebley, LD Goldstein, J Mitchell, ...
Cell reports 7 (3), 762-773, 2014
1292014
DNA damage and repair in age-related inflammation
Y Zhao, M Simon, A Seluanov, V Gorbunova
Nature Reviews Immunology 23 (2), 75-89, 2023
832023
SIRT6 promotes transcription of a subset of NRF2 targets by mono-ADP-ribosylating BAF170
S Rezazadeh, D Yang, G Tombline, M Simon, SP Regan, A Seluanov, ...
Nucleic acids research 47 (15), 7914-7928, 2019
722019
Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations
A Sakaguchi, P Sarkies, M Simon, AL Doebley, LD Goldstein, A Hedges, ...
Proceedings of the National Academy of Sciences 111 (41), E4323-E4331, 2014
522014
Transgenerational sterility of piwi mutants represents a dynamic form of adult reproductive diapause
B Heestand, M Simon, S Frenk, D Titov, S Ahmed
Cell reports 23 (1), 156-171, 2018
392018
Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation
JY Lu, M Simon, Y Zhao, J Ablaeva, N Corson, Y Choi, KLYH Yamada, ...
Cell metabolism 34 (6), 836-856. e5, 2022
342022
Caenorhabditis elegans POT-1 and POT-2 Repress Telomere Maintenance Pathways
L Shtessel, MR Lowden, C Cheng, M Simon, K Wang, S Ahmed
G3: Genes| Genomes| Genetics 3 (2), 305-313, 2013
302013
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 41 (21), e110393, 2022
222022
Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation
M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ...
Nature 572 (7767), E5-E5, 2019
192019
LINE-1 derepression in senescent cells triggers interferon and inflammaging
M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ...
Nature 566 (7742), 73, 2019
172019
Assessment of land cover changes in Lake Olbolosat region of the central Kenyan highlands using Landsat satellite imagery aided by indigenous knowledge
M Zacharia, A Elias, K Jeremiah, M Simon, LO Olang
Journal of Biodiversity Management Forestry 2, 2, 2013
112013
Accurate proteomewide measurement of methionine oxidation in aging mouse brains
JQ Bettinger, M Simon, A Korotkov, KA Welle, JR Hryhorenko, A Seluanov, ...
Journal of Proteome Research 21 (6), 1495-1509, 2022
82022
The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing
KK Billmyre, AL Doebley, M Spichal, B Heestand, T Belicard, ...
PLoS Genetics 15 (3), e1008004, 2019
72019
A hairy tale: SIRT 7 safeguards skin stem cells during aging
M Simon, S Emmrich, A Seluanov, V Gorbunova
The EMBO Journal 39 (18), e106294, 2020
42020
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 42 (3), e113326, 2023
32023
415 Line1 Derepression in Specific Retrotransposon Families in Aged Mice Leads to Cytosolic DNA and Increased Inflammation
J Martinez, M Simon, A Seluanov, V Gorbunova
Journal of Clinical and Translational Science 6 (s1), 81-81, 2022
12022
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