| Mapping the degradable kinome provides a resource for expedited degrader development KA Donovan, FM Ferguson, JW Bushman, NA Eleuteri, D Bhunia, SS Ryu, ... Cell 183 (6), 1714-1731. e10, 2020 | 172 | 2020 |
| Structure-guided development of a potent and selective non-covalent active-site inhibitor of USP7 I Lamberto, X Liu, HS Seo, NJ Schauer, RE Iacob, W Hu, D Das, ... Cell chemical biology 24 (12), 1490-1500. e11, 2017 | 160 | 2017 |
| Akkermansia muciniphila phospholipid induces homeostatic immune responses M Bae, CD Cassilly, X Liu, SM Park, BK Tusi, X Chen, J Kwon, P Filipčík, ... Nature 608 (7921), 168-173, 2022 | 150 | 2022 |
| Advances in discovering deubiquitinating enzyme (DUB) inhibitors NJ Schauer, RS Magin, X Liu, LM Doherty, SJ Buhrlage Journal of medicinal chemistry 63 (6), 2731-2750, 2019 | 138 | 2019 |
| Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism NJ Schauer, X Liu, RS Magin, LM Doherty, WC Chan, SB Ficarro, W Hu, ... Scientific reports 10 (1), 5324, 2020 | 79 | 2020 |
| Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma B Stolte, AB Iniguez, NV Dharia, AL Robichaud, AS Conway, AM Morgan, ... Journal of Experimental Medicine 215 (8), 2137-2155, 2018 | 64 | 2018 |
| Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2 JR LaRochelle, M Fodor, JM Ellegast, X Liu, V Vemulapalli, M Mohseni, ... Bioorganic & medicinal chemistry 25 (24), 6479-6485, 2017 | 52 | 2017 |
| Regulating Molecular Recognition with C-Shaped Strips Attained by Chirality-Assisted Synthesis. X Liu, ZJ Weinert, M Sharafi, C Liao, J Li, ST Schneebeli Angew. Chem. Int. Ed 54, 12772-12776, 2015 | 51 | 2015 |
| An aza-Prins cyclization approach to functionalized indolizidines from 2-allylpyrrolidines X Liu, MP McCormack, SP Waters Organic letters 14 (21), 5574-5577, 2012 | 39 | 2012 |
| Comparison of effects of midostaurin, crenolanib, quizartinib, gilteritinib, sorafenib and BLU‐285 on oncogenic mutants of KIT, CBL and FLT3 in haematological malignancies E Weisberg, C Meng, AE Case, M Sattler, HL Tiv, PC Gokhale, ... British journal of haematology 187 (4), 488-501, 2019 | 33 | 2019 |
| Proteomics-based identification of DUB substrates using selective inhibitors JW Bushman, KA Donovan, NJ Schauer, X Liu, W Hu, AC Varca, ... Cell chemical biology 28 (1), 78-87. e3, 2021 | 30 | 2021 |
| Targeting oncoproteins with a positive selection assay for protein degraders V Koduri, L Duplaquet, BL Lampson, AC Wang, AH Sabet, M Ishoey, ... Science Advances 7 (6), eabd6263, 2021 | 28 | 2021 |
| Identification and validation of selective deubiquitinase inhibitors AC Varca, D Casalena, WC Chan, B Hu, RS Magin, RM Roberts, X Liu, ... Cell chemical biology 28 (12), 1758-1771. e13, 2021 | 23 | 2021 |
| Effects of the multi‐kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia E Weisberg, C Meng, AE Case, HL Tiv, PC Gokhale, SJ Buhrlage, J Yang, ... Journal of Cellular and Molecular Medicine 24 (5), 2968-2980, 2020 | 23 | 2020 |
| Accelerating inhibitor discovery for deubiquitinating enzymes WC Chan, X Liu, RS Magin, NM Girardi, SB Ficarro, W Hu, ... Nature Communications 14 (1), 686, 2023 | 22 | 2023 |
| Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes LM Doherty, CE Mills, SA Boswell, X Liu, CT Hoyt, B Gyori, SJ Buhrlage, ... Elife 11, e72879, 2022 | 22 | 2022 |
| Precise through-space control of an abiotic electrophilic aromatic substitution reaction KE Murphy, JL Bocanegra, X Liu, HYK Chau, PC Lee, J Li, ST Schneebeli Nature communications 8 (1), 14840, 2017 | 18 | 2017 |
| Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2 J Yang, EL Weisberg, X Liu, RS Magin, WC Chan, B Hu, NJ Schauer, ... Leukemia 36 (1), 210-220, 2022 | 14 | 2022 |
| Small molecules as tools for functional assessment of deubiquitinating enzyme function RS Magin, X Liu, A Felix, AS Bratt, WC Chan, SJ Buhrlage Cell Chemical Biology 28 (7), 1090-1100, 2021 | 9 | 2021 |
| A New Entry to Azomethine Ylides from Allylic Amines and Glyoxals: Shifting the Reliance on Amino Ester Precursors. N Machamer, X Liu, SP Waters Organic Letters 16, 4996-4999, 2014 | 8 | 2014 |
