Antiviral cyclic peptides targeting the main protease of SARS-CoV-2 J Johansen-Leete, S Ullrich, SE Fry, R Frkic, MJ Bedding, A Aggarwal, ... Chemical science 13 (13), 3826-3836, 2022 | 40 | 2022 |
Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition C Franck, SR Foster, J Johansen-Leete, S Chowdhury, M Cielesh, ... Proceedings of the National Academy of Sciences 117 (23), 12657-12664, 2020 | 31 | 2020 |
Predicting antiviral resistance mutations in SARS-CoV-2 main protease with computational and experimental screening VM Sasi, S Ullrich, J Ton, SE Fry, J Johansen-Leete, RJ Payne, C Nitsche, ... Biochemistry 61 (22), 2495-2505, 2022 | 26 | 2022 |
Expressed protein selenoester ligation SS Kulkarni, EE Watson, JWC Maxwell, G Niederacher, ... Angewandte Chemie International Edition 61 (20), e202200163, 2022 | 23 | 2022 |
Discovery of potent cyclic sulfopeptide chemokine inhibitors via reprogrammed genetic code mRNA display J Johansen-Leete, T Passioura, SR Foster, RP Bhusal, DJ Ford, M Liu, ... Journal of the American Chemical Society 142 (20), 9141-9146, 2020 | 22 | 2020 |
Probing ligand binding sites on large proteins by nuclear magnetic resonance spectroscopy of genetically encoded non-canonical amino acids KB Ekanayake, MC Mahawaththa, H Qianzhu, EH Abdelkader, J George, ... Journal of Medicinal Chemistry 66 (7), 5289-5304, 2023 | 5 | 2023 |
Selenium is the chalcogen of choice for selective reporting of thioredoxin reductase activity J Johansen-Leete, RJ Payne Chem 8 (5), 1175-1177, 2022 | 3 | 2022 |
Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity MJ Bedding, C Franck, J Johansen-Leete, A Aggarwal, JWC Maxwell, ... ACS Chemical Biology 19 (1), 141-152, 2023 | 1 | 2023 |
Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS‐CoV‐2 Main Protease with Antiviral Activity K Harrison, P Carlos, S Ullrich, A Aggarwal, J Johansen-Leete, ... Chemistry–A European Journal, e202401606, 2024 | | 2024 |
Discovery of Antiviral Cyclic Peptides Targeting the Main Protease of SARS-CoV-2 via mRNA Display (preprint) J Johansen-Leete, S Ullrich, S Fry, R Frkic, M Bedding, A Aggarwal, ... | | 2021 |