Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects CQ Wang, V Krishnan, LS Tay, DWL Chin, CP Koh, JY Chooi, GSS Nah, ... Cell reports 8 (3), 767-782, 2014 | 104 | 2014 |
PRMT5 modulates splicing for genome integrity and preserves proteostasis of hematopoietic stem cells DQ Tan, Y Li, C Yang, J Li, SH Tan, DWL Chin, A Nakamura-Ishizu, ... Cell reports 26 (9), 2316-2328. e6, 2019 | 90 | 2019 |
Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy E Khattar, KZY Maung, CL Chew, A Ghosh, MMH Mok, P Lee, J Zhang, ... Nature Communications 10 (1), 5349, 2019 | 41 | 2019 |
High mitochondrial mass is associated with reconstitution capacity and quiescence of hematopoietic stem cells Y Takihara, A Nakamura-Ishizu, DQ Tan, M Fukuda, T Matsumura, ... Blood Advances 3 (15), 2323-2327, 2019 | 36 | 2019 |
Mouse models for core binding factor leukemia DWL Chin, N Watanabe-Okochi, CQ Wang, V Tergaonkar, M Osato Leukemia 29 (10), 1970-1980, 2015 | 28 | 2015 |
Cbfb deficiency results in differentiation blocks and stem/progenitor cell expansion in hematopoiesis CQ Wang, DWL Chin, JY Chooi, WJ Chng, I Taniuchi, V Tergaonkar, ... Leukemia 29 (3), 753-757, 2015 | 24 | 2015 |
RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity DWL Chin, M Sakurai, GSS Nah, L Du, B Jacob, T Yokomizo, ... Blood cancer journal 6 (1), e379-e379, 2016 | 22 | 2016 |
Adhesion, proliferation, and gene expression profile of human umbilical vein endothelial cells cultured on bilayered polyelectrolyte coatings composed of glycosaminoglycans BC Heng, PP Bezerra, QR Meng, DWL Chin, LB Koh, H Li, H Zhang, ... Biointerphases 5 (3), FA53-FA62, 2010 | 22 | 2010 |
Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis S Duarte, PS Woll, N Buza-Vidas, DWL Chin, H Boukarabila, TC Luis, ... Blood, The Journal of the American Society of Hematology 131 (15), 1712-1719, 2018 | 19 | 2018 |
Aged healthy mice acquire clonal hematopoiesis mutations DWL Chin, T Yoshizato, S Virding Culleton, F Grasso, M Barbachowska, ... Blood, The Journal of the American Society of Hematology 139 (4), 629-634, 2022 | 18 | 2022 |
Thrombopoietin maintains cell numbers of hematopoietic stem and progenitor cells with megakaryopoietic potential A O’Neill, D Chin, D Tan, A Nakamura-Ishizu, T Suda haematologica 106 (7), 1883, 2021 | 13 | 2021 |
Prolonged maintenance of hematopoietic stem cells that escape from thrombopoietin deprivation A Nakamura-Ishizu, DWL Chin, T Matsumura, DQ Tan, ... Blood, The Journal of the American Society of Hematology 137 (19), 2609-2620, 2021 | 6 | 2021 |
AT cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo E Giannakopoulou, M Lehander, S Virding Culleton, W Yang, Y Li, ... Nature Cancer 4 (10), 1474-1490, 2023 | 4 | 2023 |
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion EE Wojtowicz, JJ Mistry, V Uzun, C Hellmich, A Scoones, DW Chin, ... Genome Biology 24 (1), 152, 2023 | 1 | 2023 |
Phospholipid metabolic adaptation promotes survival of IDH2 mutant acute myeloid leukemia cells T Morishima, K Takahashi, DWL Chin, Y Wang, K Tokunaga, Y Arima, ... Cancer science 115 (1), 197-210, 2024 | | 2024 |
Oncometabolite-Independent Anti-Apoptotic Feature Via Phospholipid Metabolic Adaptation in IDH2 Mutant AML Cells T Morishima, K Takahashi, DWL Chin, K Tokunaga, Y Arima, M Matsuoka, ... Blood 140 (Supplement 1), 3012-3013, 2022 | | 2022 |
Parallel clonal and molecular profiling of hematopoietic stem cells using RNA barcoding EE Wojtowicz, J Mistry, V Uzun, A Scoones, DW Chin, L Kettyle, F Grasso, ... bioRxiv, 2022.05. 16.491933, 2022 | | 2022 |
CHARACTERIZATION OF THPO-INDEPENDENT HEMATOPOIETIC STEM CELLS WHICH ARE INDUCED TO QUIESCENCE A Nakamura-Ishizu, D Chin, T Matsumura, T Suda Experimental Hematology 76, S80, 2019 | | 2019 |
Genetic Ablation or Pharmacological Inhibition of PRMT5 Affects Maintenance of Genomic Integrity in Hematopoietic Stem Cells DQ Tan, DWL Chin, Y Li, A Nakamura-Ishizu, H Yang, T Suda Blood 130, 711, 2017 | | 2017 |
PRMT5 is required for the maintenance of genomic integrity in hematopoietic stem cells D Tan, D Chin, Y Li, KP Ng, A Nakamura-Ishizu, H Yang, T Suda Experimental Hematology 53, S48, 2017 | | 2017 |