| IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior P Chakrabarty, A Li, C Ceballos-Diaz, JA Eddy, CC Funk, B Moore, ... Neuron 85 (3), 519-533, 2015 | 378 | 2015 |
| Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain P Chakrabarty, A Rosario, P Cruz, Z Siemienski, C Ceballos-Diaz, ... PloS one 8 (6), e67680, 2013 | 199 | 2013 |
| Microglia-specific targeting by novel capsid-modified AAV6 vectors AM Rosario, PE Cruz, C Ceballos-Diaz, MR Strickland, Z Siemienski, ... Molecular Therapy Methods & Clinical Development 3, 2016 | 123 | 2016 |
| Conformational templating of α-synuclein aggregates in neuronal-glial cultures AN Sacino, MA Thomas, C Ceballos-Diaz, PE Cruz, AM Rosario, J Lewis, ... Molecular neurodegeneration 8, 1-16, 2013 | 73 | 2013 |
| Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice JI Ayers, S Fromholt, O Sinyavskaya, Z Siemienski, AM Rosario, A Li, ... Molecular Therapy 23 (1), 53-62, 2015 | 62 | 2015 |
| Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice C Ceballos-Diaz, AM Rosario, HJ Park, P Chakrabarty, A Sacino, PE Cruz, ... Molecular neurodegeneration 10, 1-13, 2015 | 59 | 2015 |
| Re-opening the critical window for estrogen therapy LA Bean, A Kumar, A Rani, M Guidi, AM Rosario, PE Cruz, TE Golde, ... Journal of Neuroscience 35 (49), 16077-16093, 2015 | 57 | 2015 |
| TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease P Chakrabarty, A Li, TB Ladd, MR Strickland, EJ Koller, JD Burgess, ... Journal of Experimental Medicine 215 (9), 2247-2264, 2018 | 55 | 2018 |
| Increased brain hemopexin levels improve outcomes after intracerebral hemorrhage JL Leclerc, J Santiago-Moreno, A Dang, AS Lampert, PE Cruz, ... Journal of Cerebral Blood Flow & Metabolism 38 (6), 1032-1046, 2018 | 38 | 2018 |
| A human monoclonal IgG that binds Aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo Y Levites, B O'Nuallain, RD Puligedda, T Ondrejcak, SP Adekar, C Chen, ... Journal of Neuroscience 35 (16), 6265-6276, 2015 | 35 | 2015 |
| Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice T Prasad, P Zhu, A Verma, P Chakrabarty, AM Rosario, TE Golde, Q Li Scientific Reports 7 (1), 3222, 2017 | 34 | 2017 |
| Complex relationships between substrate sequence and sensitivity to alterations in γ-secretase processivity induced by γ-secretase modulators JI Jung, Y Ran, PE Cruz, AM Rosario, TB Ladd, TL Kukar, EH Koo, ... Biochemistry 53 (12), 1947-1957, 2014 | 25 | 2014 |
| APP-mediated signaling prevents memory decline in Alzheimer’s disease mouse model C Deyts, M Clutter, N Pierce, P Chakrabarty, TB Ladd, A Goddi, ... Cell reports 27 (5), 1345-1355. e6, 2019 | 24 | 2019 |
| Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo KN McFarland, C Ceballos, A Rosario, T Ladd, B Moore, G Golde, ... Life Science Alliance 4 (7), 2021 | 19 | 2021 |
| Il-10 signaling reduces survival in mouse models of synucleinopathy SG Cockey, KN McFarland, EJ Koller, MMT Brooks, ... npj Parkinson's Disease 7 (1), 30, 2021 | 10 | 2021 |
| Immunological response and durability of expression following sequential intravitreal administration of AAV2. 7m8 gene therapy to the contralateral eye in non-human primates D Cepeda, E Yeh, J Nieves, CC Diaz, A Rosario, J Greengard, C Gelfman, ... Investigative Ophthalmology & Visual Science 60 (9), 2910-2910, 2019 | 3 | 2019 |
| O3‐04‐06: Functionalized intrabodies as potential tau targeting therapy Y Levites, T Golde, PE Cruz, AM Rosario, GD Sinyavskiy Alzheimer's & Dementia 11 (7S_Part_5), P227-P227, 2015 | 1 | 2015 |
| Biodistribution and pharmacokinetics of AAVRh. 10-A1AT mediated gene therapy in humanized-liver mice as a predictor of A1AT human expression levels following intravenous delivery D Cepeda, B Belbellaa, E Yeh, A Rosario, J Nieves, DO Morales, ... HUMAN GENE THERAPY 30 (11), A143-A143, 2019 | | 2019 |
| In vivo screening of an adeno-associated virus capsid library in non-human primate eyes identifies a novel AAV variant with superior retinal penetration and transduction by … D Cepeda, A Keravala, J Nieves, R Aeran, H To, TN Qureshi, AM Rosario, ... HUMAN GENE THERAPY 30 (11), A20-A20, 2019 | | 2019 |
| Evaluating central nervous system promoters using double strand adeno-associated virus 6 triple mutants (T492V-Y705F-Y731F) virus PE Cruz, C Ceballos, V Truong, A Rosario, X Liu, S Modrow, M Parianos, ... HUMAN GENE THERAPY 29 (12), A154-A155, 2018 | | 2018 |
Pedro E. CruzAssistant Professor, Universidade AtlânticaVerified email at ecbio.com
