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Malene Brohus
Malene Brohus
Postdoctoral researcher in Biotechnology, Aalborg University, Denmark
Verified email at bio.aau.dk
Title
Cited by
Cited by
Year
Human calmodulin mutations
HH Jensen, M Brohus, M Nyegaard, MT Overgaard
Frontiers in molecular neuroscience 11, 396, 2018
962018
Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel
K Wang, C Holt, J Lu, M Brohus, KT Larsen, MT Overgaard, R Wimmer, ...
Proceedings of the National Academy of Sciences 115 (45), E10556-E10565, 2018
462018
Biochemical foundations of health and energy conservation in hibernating free-ranging subadult brown bear Ursus arctos
KG Welinder, R Hansen, MT Overgaard, M Brohus, M Sønderkær, ...
Journal of Biological Chemistry 291 (43), 22509-22523, 2016
442016
Infanticide vs. inherited cardiac arrhythmias
M Brohus, T Arsov, DA Wallace, HH Jensen, M Nyegaard, L Crotti, ...
EP Europace 23 (3), 441-450, 2021
332021
Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+ binding and cause misfolding
K Wang, M Brohus, C Holt, MT Overgaard, R Wimmer, F Van Petegem
The Journal of physiology 598 (6), 1169-1186, 2020
302020
Ca2+-dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains
M Brohus, MT Søndergaard, SR Wayne Chen, F Van Petegem, ...
Biochemical Journal 476 (2), 193-209, 2019
282019
The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor
C Holt, L Hamborg, K Lau, M Brohus, AB Sørensen, KT Larsen, ...
Journal of Biological Chemistry 295 (22), 7620-7634, 2020
222020
The insulin-like growth factor system in the long-lived naked mole-rat
M Brohus, V Gorbunova, CG Faulkes, MT Overgaard, CA Conover
PLoS One 10 (12), e0145587, 2015
202015
Role of cardiac ryanodine receptor calmodulin‐binding domains in mediating the action of arrhythmogenic calmodulin N‐domain mutation N54I
MT Søndergaard, Y Liu, W Guo, J Wei, R Wang, M Brohus, MT Overgaard, ...
The FEBS Journal 287 (11), 2256-2280, 2020
152020
Diminished inhibition and facilitated activation of RyR2‐mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations
MT Søndergaard, Y Liu, M Brohus, W Guo, A Nani, C Carvajal, M Fill, ...
The FEBS Journal 286 (22), 4554-4578, 2019
142019
Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations
MT Sondergaard, Y Liu, M Brohus, W Guo, A Nani, C Carvajal, M Fill, ...
FEBS JOURNAL 286 (22), 4554-4578, 2019
92019
Abnormal IGF-binding protein profile in the bone marrow of multiple myeloma patients
L Bieghs, M Brohus, IB Kristensen, N Abildgaard, M Bøgsted, HE Johnsen, ...
PLoS One 11 (4), e0154256, 2016
92016
Human calmodulin mutations cause arrhythmia and affect neuronal function in C. elegans
HH Jensen, MT Frantzen, JL Wesseltoft, AO Busuioc, KV Møller, M Brohus, ...
Human Molecular Genetics 32 (12), 2068-2083, 2023
62023
Calmodulin mutations affecting Gly114 impair binding to the NaV1. 5 IQ-domain
M Brohus, AO Busuioc, R Wimmer, M Nyegaard, MT Overgaard
Frontiers in pharmacology 14, 1210140, 2023
42023
The first junior European Calcium Society meeting: calcium research across scales, Kingdoms and countries
BP Diercks, HH Jensen, SB Chalmers, E Coode, MB Vaughan, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (6), 118999, 2021
32021
Hypothyroidism in hibernating brown bears
AM Frøbert, CG Nielsen, M Brohus, J Kindberg, O Fröbert, MT Overgaard
Thyroid research 16 (1), 3, 2023
12023
Circulating insulin-like growth factor system adaptations in hibernating brown bears indicate increased tissue IGF availability
AM Frøbert, M Brohus, TS Roesen, J Kindberg, O Fröbert, CA Conover, ...
American Journal of Physiology-Endocrinology and Metabolism 323 (3), E307-E318, 2022
12022
Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats
AM Frøbert, JNC Toews, CG Nielsen, M Brohus, J Kindberg, N Jessen, ...
Physiological and Biochemical Zoology 95 (5), 365-378, 2022
12022
Plasma proteomics data from hibernating and active Scandinavian brown bears
AM Frøbert, S Gregersen, M Brohus, KG Welinder, J Kindberg, O Fröbert, ...
Data in Brief 41, 107959, 2022
12022
Characterization and comparison of recombinant full‐length ursine and human sex hormone‐binding globulin
AM Frøbert, M Brohus, JNC Toews, P Round, O Fröbert, GL Hammond, ...
FEBS open bio 12 (2), 362-378, 2022
12022
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