Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 483 | 2012 |
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes I Miguel-Escalada, S Bonàs-Guarch, I Cebola, J Ponsa-Cobas, ... Nature genetics 51 (7), 1137-1148, 2019 | 232 | 2019 |
Human pancreatic β cell lncRNAs control cell-specific regulatory networks I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ... Cell metabolism 25 (2), 400-411, 2017 | 222 | 2017 |
Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development J Soyer, L Flasse, W Raffelsberger, A Beucher, C Orvain, B Peers, ... Development 137 (2), 203-212, 2010 | 189 | 2010 |
Changes in the coding and non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury PJ Arthur-Farraj, CC Morgan, M Adamowicz, JA Gomez-Sanchez, ... Cell reports 20 (11), 2719-2734, 2017 | 174 | 2017 |
Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival G Mellitzer, A Beucher, V Lobstein, P Michel, S Robine, M Kedinger, ... The Journal of clinical investigation 120 (5), 1708-1721, 2010 | 108 | 2010 |
The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice A Beucher, E Gjernes, C Collin, M Courtney, A Meunier, P Collombat, ... PloS one 7 (5), e36449, 2012 | 96 | 2012 |
HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer M Kalisz, E Bernardo, A Beucher, MA Maestro, N Del Pozo, I Millán, ... The EMBO journal 39 (9), e102808, 2020 | 50 | 2020 |
Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production J Piccand, C Vagne, F Blot, A Meunier, A Beucher, P Strasser, ML Lund, ... Molecular metabolism 29, 24-39, 2019 | 50 | 2019 |
Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development A Beucher, M Martín, C Spenle, M Poulet, C Collin, G Gradwohl Developmental biology 361 (2), 277-285, 2012 | 46 | 2012 |
Long non-coding RNAs as local regulators of pancreatic islet transcription factor genes B Font-Cunill, L Arnes, J Ferrer, L Sussel, A Beucher Frontiers in genetics 9, 421004, 2018 | 23 | 2018 |
The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A A Beucher, I Miguel-Escalada, D Balboa, MG De Vas, MA Maestro, ... Nature Cell Biology 24 (10), 1528-1540, 2022 | 16 | 2022 |
Endocrine pancreatic tissue plasticity in obese humans is associated with cytoplasmic expression of PBX-1 in pancreatic ductal cells G Muharram, A Beucher, E Moerman, S Belaı, V Gmyr, B Vandewalle, ... Biochemical and biophysical research communications 333 (4), 1153-1159, 2005 | 13 | 2005 |
Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn’s disease, and celiac disease T Braun, KE Sosnovski, A Amir, M BenShoshan, KL VanDussen, R Karns, ... JCI insight 8 (14), 2023 | 11 | 2023 |
Genetic regulation of RNA splicing in human pancreatic islets G Atla, S Bonàs-Guarch, M Cuenca-Ardura, A Beucher, DJM Crouch, ... Genome biology 23 (1), 196, 2022 | 11 | 2022 |
One-step dual CRISPR/Cas9 guide RNA cloning protocol A Beucher, I Cebola | 7 | 2019 |
HASTER is a transcriptional stabilizer of HNF1A A Beucher, I Miguel-Escalada, D Balboa, MG De Vas, MA Maestro, ... bioRxiv, 2021.05. 12.443907, 2021 | 2 | 2021 |
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice JM Ramos-Pittol, I Fernandes-Freitas, A Milona, SM Manchishi, ... Nature Communications 14 (1), 3076, 2023 | 1 | 2023 |
Genetic regulation of RNA splicing in human pancreatic islets G Atla, S Bonas-Guarch, A Beucher, M Cuenca-Ardura, J Garcia-Hurtado, ... bioRxiv, 2021.11. 11.468254, 2021 | 1 | 2021 |
Identification of a transcription factor that modulates ER [alpha]-Dependent Hypothalamic Estrogen Sensing I Fernandes-Freitas, A Milona, J Ramos-Pittol, S Manchishi, K Rainbow, ... Endocrine Abstracts 86, 2022 | | 2022 |