Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus P Mistry, S Nakabo, L O’Neil, RR Goel, K Jiang, C Carmona-Rivera, ... Proceedings of the National Academy of Sciences 116 (50), 25222-25228, 2019 | 193 | 2019 |
Neutrophils in rheumatoid arthritis: breaking immune tolerance and fueling disease LJ O’Neil, MJ Kaplan Trends in molecular medicine 25 (3), 215-227, 2019 | 170 | 2019 |
Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2 C Carmona-Rivera, SS Khaznadar, KW Shwin, JA Irizarry-Caro, LJ O’Neil, ... Blood, The Journal of the American Society of Hematology 134 (4), 395-406, 2019 | 124 | 2019 |
Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa AS Byrd, C Carmona-Rivera, LJ O’Neil, PM Carlucci, C Cisar, ... Science translational medicine 11 (508), eaav5908, 2019 | 119 | 2019 |
Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism S Gupta, S Nakabo, LP Blanco, LJ O’Neil, G Wigerblad, RR Goel, P Mistry, ... Proceedings of the National Academy of Sciences 117 (28), 16481-16491, 2020 | 113 | 2020 |
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus RR Goel, X Wang, LJ O’Neil, S Nakabo, K Hasneen, S Gupta, ... Proceedings of the National Academy of Sciences 117 (10), 5409-5419, 2020 | 91 | 2020 |
Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7–dependent lupus Y Liu, YL Lightfoot, N Seto, C Carmona-Rivera, E Moore, R Goel, L O’Neil, ... JCI insight 3 (23), 2018 | 76 | 2018 |
Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis LJ O’Neil, A Barrera-Vargas, D Sandoval-Heglund, J Merayo-Chalico, ... Science Advances 6 (44), eabd2688, 2020 | 69 | 2020 |
The role of neutrophils and neutrophil extracellular traps in vascular damage in systemic lupus erythematosus LJ O’Neil, MJ Kaplan, C Carmona-Rivera Journal of clinical medicine 8 (9), 1325, 2019 | 57 | 2019 |
Single-cell analysis reveals the range of transcriptional states of circulating human neutrophils G Wigerblad, Q Cao, S Brooks, F Naz, M Gadkari, K Jiang, S Gupta, ... The Journal of Immunology 209 (4), 772-782, 2022 | 46 | 2022 |
Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis LJ O'Neil, CB Oliveira, X Wang, M Navarrete, A Barrera-Vargas, ... Annals of the Rheumatic Diseases 82 (5), 630-638, 2023 | 31 | 2023 |
Autoantibodies present in hidradenitis suppurativa correlate with disease severity and promote the release of proinflammatory cytokines in macrophages C Carmona-Rivera, LJ O’Neil, E Patino-Martinez, WD Shipman, C Zhu, ... Journal of Investigative Dermatology 142 (3), 924-935, 2022 | 22 | 2022 |
Association of a serum protein signature with rheumatoid arthritis development LJ O’Neil, V Spicer, I Smolik, X Meng, RR Goel, V Anaparti, J Wilkins, ... Arthritis & Rheumatology 73 (1), 78-88, 2021 | 21 | 2021 |
Anti-carbamylated LL37 antibodies promote pathogenic bone resorption in rheumatoid arthritis LJ O’Neil, CB Oliveira, D Sandoval-Heglund, A Barrera-Vargas, ... Frontiers in Immunology 12, 715997, 2021 | 17 | 2021 |
Striking a balance in rheumatoid arthritis prevention trials LJ O’Neil, KD Deane Nature Reviews Rheumatology 17 (7), 385-386, 2021 | 11 | 2021 |
Proteomic approaches to defining remission and the risk of relapse in rheumatoid arthritis LJ O’Neil, P Hu, Q Liu, MM Islam, V Spicer, J Rech, A Hueber, V Anaparti, ... Frontiers in Immunology 12, 729681, 2021 | 8 | 2021 |
Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis V Anaparti, S Tanner, C Zhang, L O’Neil, I Smolik, X Meng, AJ Marshall, ... Frontiers in immunology 13, 932627, 2022 | 6 | 2022 |
Expansion of Alternative Autoantibodies Does Not Follow the Evolution of Anti–Citrullinated Protein Antibodies in Preclinical Rheumatoid Arthritis: An Analysis in At‐Risk First … V Anaparti, I Smolik, X Meng, L O’Neil, MA Jantz, MJ Fritzler, ... Arthritis & Rheumatology 73 (5), 740-749, 2021 | 6 | 2021 |
NETched in stone LJ O’Neil, MJ Kaplan Immunity 51 (3), 413-414, 2019 | 6 | 2019 |
Modifiable risk factors linked to the development of rheumatoid arthritis: evidence, immunological mechanisms and prevention JA Maisha, HS El-Gabalawy, LJ O’Neil Frontiers in Immunology 14, 1221125, 2023 | 5 | 2023 |