| IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis SB Coffelt, K Kersten, CW Doornebal, J Weiden, K Vrijland, CS Hau, ... Nature 522 (7556), 345-348, 2015 | 1583 | 2015 |
| Matrix metalloproteinase-14 (MT1-MMP)–mediated endoglin shedding inhibits tumor angiogenesis LJAC Hawinkels, P Kuiper, E Wiercinska, HW Verspaget, Z Liu, E Pardali, ... Cancer research 70 (10), 4141-4150, 2010 | 358 | 2010 |
| Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts L Hawinkels, M Paauwe, HW Verspaget, E Wiercinska, JM Van Der Zon, ... Oncogene 33 (1), 97-107, 2014 | 312 | 2014 |
| Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy MF Fransen, M Schoonderwoerd, P Knopf, MGM Camps, LJAC Hawinkels, ... JCI insight 3 (23), 2018 | 259 | 2018 |
| VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis LJAC Hawinkels, K Zuidwijk, HW Verspaget, ESM de Jonge-Muller, ... European journal of cancer 44 (13), 1904-1913, 2008 | 241 | 2008 |
| Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis SI Cunha, E Pardali, M Thorikay, C Anderberg, L Hawinkels, MJ Goumans, ... Journal of Experimental Medicine 207 (1), 85-100, 2010 | 227 | 2010 |
| Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling FF Zhou, Y Drabsch, TJA Dekker, AG De Vinuesa, Y Li, LJAC Hawinkels, ... Nature communications 5 (1), 3388, 2014 | 195 | 2014 |
| Exploring anti-TGF-β therapies in cancer and fibrosis LJAC Hawinkels, P Ten Dijke Growth factors 29 (4), 140-152, 2011 | 193 | 2011 |
| Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer FJGM Kubben, CFM Sier, LJAC Hawinkels, H Tschesche, W van Duijn, ... European journal of cancer 43 (12), 1869-1876, 2007 | 191 | 2007 |
| Endoglin expression on cancer-associated fibroblasts regulates invasion and stimulates colorectal cancer metastasis M Paauwe, MJA Schoonderwoerd, RFCP Helderman, TJ Harryvan, ... Clinical Cancer Research 24 (24), 6331-6344, 2018 | 158 | 2018 |
| BMP-9 interferes with liver regeneration and promotes liver fibrosis K Breitkopf-Heinlein, C Meyer, C König, H Gaitantzi, A Addante, ... Gut 66 (5), 939-954, 2017 | 128 | 2017 |
| MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients AMJ Langers, HW Verspaget, L Hawinkels, F Kubben, W Van Duijn, ... British journal of cancer 106 (9), 1495-1498, 2012 | 123 | 2012 |
| Selecting targets for tumor imaging: an overview of cancer-associated membrane proteins MC Boonstra, SWL De Geus, HAJM Prevoo, LJAC Hawinkels, ... Biomarkers in cancer 8, BIC. S38542, 2016 | 120 | 2016 |
| Tissue level, activation and cellular localisation of TGF-β1 and association with survival in gastric cancer patients LJAC Hawinkels, HW Verspaget, W van Duijn, JM van der Zon, K Zuidwijk, ... British journal of cancer 97 (3), 398-404, 2007 | 117 | 2007 |
| Elevated TGFβ–Smad signalling in experimental Pkd1 models and human patients with polycystic kidney disease S Hassane, WN Leonhard, A van der Wal, LJAC Hawinkels, ... The Journal of pathology 222 (1), 21-31, 2010 | 115 | 2010 |
| The prognostic role of TGF-β signaling pathway in breast cancer patients EM De Kruijf, TJA Dekker, L Hawinkels, H Putter, V Smit, JR Kroep, ... Annals of oncology 24 (2), 384-390, 2013 | 89 | 2013 |
| Endoglin: beyond the endothelium MJA Schoonderwoerd, MJTH Goumans, LJAC Hawinkels Biomolecules 10 (2), 289, 2020 | 87 | 2020 |
| The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC PW Voorneveld, LL Kodach, RJ Jacobs, CJM Van Noesel, ... British journal of cancer 112 (1), 122-130, 2015 | 87 | 2015 |
| ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis Z Liu, F Lebrin, JA Maring, S van den Driesche, S van der Brink, ... PloS one 9 (1), e86273, 2014 | 87 | 2014 |
| Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer M Paauwe, RC Heijkants, CH Oudt, GW Van Pelt, C Cui, CP Theuer, ... Oncogene 35 (31), 4069-4079, 2016 | 79 | 2016 |
