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Hamsell M. Alvarez
Hamsell M. Alvarez
Director, Immuno-Oncology Discovery, AbbVie
Verified email at abbvie.com
Title
Cited by
Cited by
Year
Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation
HM Alvarez, Y Xue, CD Robinson, MA Canalizo-Hernández, RG Marvin, ...
Science 327 (5963), 331-334, 2010
1772010
Modeling Nickel Hydrogenases:  Synthesis and Structure of a Distorted Octahedral Complex with an Unprecedented [NiS4H2] Core
HM Alvarez, M Krawiec, BT Donovan-Merkert, M Fouzi, D Rabinovich
Inorganic Chemistry 40 (23), 5736-5737, 2001
842001
Homoleptic Group 12 Metal Bis(mercaptoimidazolyl)borate Complexes M(BmR)2 (M = Zn, Cd, Hg)
HM Alvarez, TB Tran, MA Richter, DM Alyounes, D Rabinovich, JM Tanski, ...
Inorganic chemistry 42 (6), 2149-2156, 2003
722003
Poly (mercaptoimidazolyl) borate chemistry and the predominance of κ3-S, S, H over κ2-S, S or κ3-S, S, S coordination modes: unexpected formation of square pyramidal Ni (II …
HM Alvarez, JM Tanski, D Rabinovich
Polyhedron 23 (2-3), 395-403, 2004
462004
An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy
S Chan, N Belmar, S Ho, B Rogers, M Stickler, M Graham, E Lee, N Tran, ...
Nature cancer 3 (3), 337-354, 2022
432022
Thallium (I) bis (mercaptoimidazolyl) borates
HM Alvarez, PA Gillespie, CD Gause, AL Rheingold, JA Golen, ...
Polyhedron 23 (4), 617-622, 2004
372004
Effects of PEGylation and immune complex formation on the pharmacokinetics and biodistribution of recombinant interleukin 10 in mice
HM Alvarez, OY So, SC Hsieh, N Shinsky-Bjorde, H Ma, Y Song, Y Pang, ...
Drug Metabolism and Disposition 40 (2), 360-373, 2012
322012
Epitope and Fc-mediated cross-linking, but not high affinity, are critical for antitumor activity of CD137 agonist antibody with reduced liver toxicity
SK Ho, Z Xu, A Thakur, M Fox, SS Tan, E DiGiammarino, L Zhou, M Sho, ...
Molecular cancer therapeutics 19 (4), 1040-1051, 2020
312020
Murinization and H chain isotype matching of the anti-Gitr antibody Dta-1 reduces immunogenicity-mediated anaphylaxis in C57bl/6 mice
NA Belmar, SW Chan, MI Fox, JA Samayoa, MM Stickler, NN Tran, ...
The Journal of Immunology 198 (11), 4502-4512, 2017
62017
Evaluation of efficacy metrics for in vivo experiments with immuno-oncology therapeutic agents
C Zhang, Y Sun, HM Alvarez, Y Akamatsu, F Harding, SS Tan, M Fox, ...
Cancer Research 80 (16_Supplement), 1615-1615, 2020
2020
Structural implications for GITR agonism in immunotherapies
H Alvarez, B Rogers, S Chan, L Bigelow, S Cichanowicz, M Lake, ...
JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019
2019
Murinization of an anti-GITR IgG2c antibody DTA-1 inhibits immunogenicity-mediated anaphylaxis in C57BL/6J mice
H Alvarez, N Belmar, M Fox, J Samayoa, S Chan, D Hollenbaugh, ...
Journal for ImmunoTherapy of Cancer 3 (Suppl 2), P182, 2015
2015
The Role of FcRn in the Disposition, Metabolism and Pharmacokinetics of Soluble Non‐Crosslinking Immune Complexes
HM Alvarez, OY So, SC Hsieh, N Shinsky‐Bjorde, H Ma, Y Song, Y Pang, ...
The FASEB Journal 27, 270.7-270.7, 2013
2013
Insights on the intracellular mechanism of action of the anticancer and antiangiogenic copper chelator drug: Ammonium tetrathiomolybdate (TM)
HM Alvarez
Northwestern University, 2008
2008
Insights on the molecular mechanism of action of the antiangiogenic copper chelator drug: ammonium tetrathiomolybdate
HM Alvarez, TV O'Halloran, R Kelly, JE Penner-Hahn, B Lai
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 233, 461-461, 2007
2007
CCDC 208142: Experimental Crystal Structure Determination
MA Richter, DM Alyounes, M Krawiec, TB Tran, JM Tanski, D Rabinovich, ...
The Cambridge Structural Database, 2003
2003
CCDC 208145: Experimental Crystal Structure Determination
D Rabinovich, MA Richter, HM Alvarez, JM Tanski, M Krawiec, ...
The Cambridge Structural Database, 2003
2003
Five-coordinate nickel poly (mercaptoimidazolyl) borate complexes.
HM Alvarez, JM Tanski, D Rabinovich
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 224, U677-U677, 2002
2002
Bis (mercaptoimidazolyl) borate complexes.
HM Alvarez, D Rabinovich
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 223, A16-A16, 2002
2002
New synthetic models of nickel hydrogenases.
D Rabinovich, HM Alvarez
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 223, A68-A68, 2002
2002
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