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N. Connor Payne
N. Connor Payne
Post-Doctoral Fellow at Harvard T.H. Chan School of Public Health
Verified email at hsph.harvard.edu
Title
Cited by
Cited by
Year
Bright and stable luminescent probes for target engagement profiling in live cells
NC Payne, AS Kalyakina, K Singh, MA Tye, R Mazitschek
Nature chemical biology 17 (11), 1168-1177, 2021
362021
Comparison of the redox chemistry of sulfur-and selenium-containing analogs of uracil
NC Payne, A Geissler, A Button, AR Sasuclark, AL Schroll, EL Ruggles, ...
Free Radical Biology and Medicine 104, 249-261, 2017
322017
A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader
NC Payne, S Maksoud, BA Tannous, R Mazitschek
Cell chemical biology 29 (8), 1333-1340. e5, 2022
202022
Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors
NC Payne, R Mazitschek
Cell Chemical Biology, 2022
162022
The prolyl-tRNA synthetase inhibitor halofuginone inhibits SARS-CoV-2 infection
DR Sandoval, TM Clausen, C Nora, AP Cribbs, A Denardo, AE Clark, ...
bioRxiv, 2021.03. 22.436522, 2021
132021
Can dimedone be used to study selenoproteins? An investigation into the reactivity of dimedone toward oxidized forms of selenocysteine
NC Payne, DR Barber, EL Ruggles, RJ Hondal
Protein Science 28 (1), 41-55, 2019
132019
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance
MA Tye, NC Payne, C Johansson, K Singh, SA Santos, L Fagbami, A Pant, ...
Nature Communications 13 (1), 4976, 2022
122022
Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly
RJ Adamson, NC Payne, SG Bartual, R Mazitschek, AN Bullock
Free Radical Biology and Medicine 204, 215-225, 2023
112023
Tiny Titans: Nanobodies as Powerful Tools for TR‐FRET Assay Development
N Connor Payne, R Mazitschek
Analysis & Sensing 2 (6), e202200020, 2022
82022
Rapid “mix and read” assay for scalable detection of SARS-CoV-2 antibodies in patient plasma
H Yue, RP Nowak, D Overwijn, NC Payne, S Fischinger, C Atyeo, ...
medRxiv, 2020.09. 01.20184101, 2020
72020
Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma
K Kurata, A James-Bott, MA Tye, L Yamamoto, MK Samur, YT Tai, ...
Blood cancer journal 13 (1), 12, 2023
42023
The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation
S Ichikawa, NC Payne, W Xu, CF Chang, N Vallavoju, S Frome, ...
Cell Chemical Biology, 2023
32023
Inhibiting the Keap1/Nrf2 Protein‐Protein Interaction with Protein‐Like Polymers
KP Carrow, HL Hamilton, MP Hopps, Y Li, B Qiao, NC Payne, ...
Advanced Materials, 2311467, 2024
12024
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes
X Xie, O Zhang, MJR Yeo, C Lee, SA Harry, L Paul, Y Li, NC Payne, ...
bioRxiv, 2024.05. 14.593970, 2024
12024
Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology
NC Payne, S Ichikawa, CM Woo, R Mazitschek
STAR protocols 5 (2), 103129, 2024
2024
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia
ZC Rosenthal, DM Fass, NC Payne, A She, D Patnaik, KM Hennig, ...
Scientific reports 14 (1), 9064, 2024
2024
A lysate-based TR-FRET approach for the facile quantification of cellular drug concentration
NC Payne, R Mazitschek
2024
Asymmetric Engagement of Dimeric CRL3KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes
MJR Yeo, O Zhang, X Xie, E Nam, NC Payne, PM Gosavi, HS Kwok, I Iram, ...
bioRxiv, 2024.05. 14.593897, 2024
2024
Discovery of First-in-Class Small Molecule Inhibitors of the IRF4-PU. 1/Spi-B Interaction
MP Agius, L Hevenor, NC Payne, R Mazitschek, HS Seo, S Dhe-Paganon, ...
Blood 142, 3635, 2023
2023
Tr-fret based assay for detection of antibodies in serological samples
E Fischer, R Nowak, YUE Hong, D Overwijn, R Mazitschek, NC Payne
US Patent App. 18/020,800, 2023
2023
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Articles 1–20