| Hydration Is a Major Determinant of the G-Quadruplex Stability and Conformation of the Human Telomere 3′ Sequence of d(AG3(TTAG3)3) MC Miller, R Buscaglia, JB Chaires, AN Lane, JO Trent Journal of the American Chemical Society 132 (48), 17105-17107, 2010 | 219 | 2010 |
| Biophysical studies of the c-MYC NHE III1 promoter: model quadruplex interactions with a cationic porphyrin MW Freyer, R Buscaglia, K Kaplan, D Cashman, LH Hurley, EA Lewis Biophysical journal 92 (6), 2007 | 169 | 2007 |
| Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection R Buscaglia, MC Miller, WL Dean, RD Gray, AN Lane, JO Trent, ... Nucleic acids research 41 (16), 7934-7946, 2013 | 142 | 2013 |
| Populated intermediates in the thermal unfolding of the human telomeric quadruplex RD Gray, R Buscaglia, JB Chaires Journal of the American Chemical Society 134 (40), 16834-16844, 2012 | 120 | 2012 |
| Induction of G-quadruplex DNA structure by Zn (II) 5, 10, 15, 20-tetrakis (N-methyl-4-pyridyl) porphyrin AJ Bhattacharjee, K Ahluwalia, S Taylor, O Jin, JM Nicoludis, R Buscaglia, ... Biochimie 93 (8), 1297-1309, 2011 | 101 | 2011 |
| Modeling complex equilibria in isothermal titration calorimetry experiments: thermodynamic parameters estimation for a three-binding-site model VH Le, R Buscaglia, JB Chaires, EA Lewis Analytical biochemistry 434 (2), 233-241, 2013 | 97 | 2013 |
| Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4 HT Le, MC Miller, R Buscaglia, WL Dean, PA Holt, JB Chaires, JO Trent Organic & biomolecular chemistry 10 (47), 9393-9404, 2012 | 74 | 2012 |
| Studies on the site and mode of TMPyP4 interactions with Bcl-2 promoter sequence G-Quadruplexes N Nagesh, R Buscaglia, JM Dettler, EA Lewis Biophysical journal 98 (11), 2628-2633, 2010 | 65 | 2010 |
| An improved model for the hTERT promoter quadruplex JB Chaires, JO Trent, RD Gray, WL Dean, R Buscaglia, SD Thomas, ... PLoS One 9 (12), e115580, 2014 | 64 | 2014 |
| Biophysical characterization of an ensemble of intramolecular i-motifs formed by the human c-MYC NHE III1 P1 promoter mutant sequence JM Dettler, R Buscaglia, JJ Cui, D Cashman, M Blynn, EA Lewis Biophysical journal 99 (2), 561-567, 2010 | 49 | 2010 |
| Binding of netropsin to several DNA constructs: Evidence for at least two different 1: 1 complexes formed from an–AATT-containing ds-DNA construct and a single minor groove … MW Freyer, R Buscaglia, D Cashman, S Hyslop, WD Wilson, JB Chaires, ... Biophysical chemistry 126 (1-3), 186-196, 2007 | 49 | 2007 |
| Binding of netropsin and 4, 6-diamidino-2-phenylindole to an A2T2 DNA hairpin: a comparison of biophysical techniques MW Freyer, R Buscaglia, B Nguyen, WD Wilson, EA Lewis Analytical biochemistry 355 (2), 259-266, 2006 | 49 | 2006 |
| Molecular modeling and biophysical analysis of the c-MYC NHE-III1 silencer element DJ Cashman, R Buscaglia, MW Freyer, J Dettler, LH Hurley, EA Lewis Journal of molecular modeling 14, 93-101, 2008 | 47 | 2008 |
| Thermodynamic characterization of human telomere quadruplex unfolding R Buscaglia, RD Gray, JB Chaires Biopolymers 99 (12), 1006-1018, 2013 | 45 | 2013 |
| 2-aminopurine as a probe for quadruplex loop structures RD Gray, L Petraccone, R Buscaglia, JB Chaires G-Quadruplex DNA: Methods and Protocols, 121-136, 2010 | 40 | 2010 |
| DSC deconvolution of the structural complexity of c-MYC P1 promoter G-quadruplexes JM Dettler, R Buscaglia, VH Le, EA Lewis Biophysical journal 100 (6), 1517-1525, 2011 | 39 | 2011 |
| Break in the heat capacity change at 303 K for complex binding of netropsin to AATT containing hairpin DNA constructs MW Freyer, R Buscaglia, A Hollingsworth, J Ramos, M Blynn, R Pratt, ... Biophysical journal 92 (7), 2516-2522, 2007 | 31 | 2007 |
| A discovery funnel for nucleic acid binding drug candidates PA Holt, R Buscaglia, JO Trent, JB Chaires Drug development research 72 (2), 178-186, 2011 | 29 | 2011 |
| An investigation of G-quadruplex structural polymorphism in the human telomere using a combined approach of hydrodynamic bead modeling and molecular dynamics simulation HT Le, WL Dean, R Buscaglia, JB Chaires, JO Trent The Journal of Physical Chemistry B 118 (20), 5390-5405, 2014 | 24 | 2014 |
| Calculation of Hydrodynamic Properties for G-Quadruplex Nucleic Acid Structures from in silico Bead Models HT Le, R Buscaglia, WL Dean, JB Chaires, JO Trent Quadruplex Nucleic Acids, 179-210, 2013 | 22 | 2013 |
Jonathan ChairesProfessor, James Graham Brown Cancer Center, University of LouisvilleVerified email at louisville.edu
