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Yuchen Xu
Yuchen Xu
Verified email at emory.edu
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Year
De novo GRIN variants in NMDA receptor M2 channel pore‐forming loop are associated with neurological diseases
J Li, J Zhang, W Tang, RK Mizu, H Kusumoto, W XiangWei, Y Xu, W Chen, ...
Human mutation 40 (12), 2393-2413, 2019
592019
Sex-differential DNA methylation and associated regulation networks in human brain implicated in the sex-biased risks of psychiatric disorders
Y Xia, R Dai, K Wang, C Jiao, C Zhang, Y Xu, H Li, X Jing, Y Chen, ...
Molecular psychiatry 26 (3), 835-848, 2021
542021
Heterogeneous clinical and functional features of GRIN2D-related developmental and epileptic encephalopathy
W XiangWei, V Kannan, Y Xu, GJ Kosobucki, AJ Schulien, H Kusumoto, ...
Brain 142 (10), 3009-3027, 2019
522019
Recurrent seizure‐related GRIN1 variant: Molecular mechanism and targeted therapy
Y Xu, R Song, W Chen, K Strong, D Shrey, S Gedela, SF Traynelis, ...
Annals of clinical and translational neurology 8 (7), 1480-1494, 2021
232021
The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus
J Piard, M Béreau, W XiangWei, T Wirth, D Amsallem, L Buisson, ...
Movement Disorders 35 (7), 1224-1232, 2020
152020
CpG methylation signature defines human temporal lobe epilepsy and predicts drug‐resistant
W Xiao, C Liu, K Zhong, S Ning, R Hou, N Deng, Y Xu, Z Luo, Y Fu, ...
CNS Neuroscience & Therapeutics 26 (10), 1021-1030, 2020
132020
A conjoint analysis of epilepsy and migraine through network-and-pathway-based method
Y Shu, Y Xu, W Xiao, X Deng, Y Zeng, R Chen, B Xiao, H Long
Annals of palliative medicine 9 (5), 2642653-2642653, 2020
82020
A de novo GRIN1 Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology
J Zhang, W Tang, NK Bhatia, Y Xu, N Paudyal, D Liu, S Kim, R Song, ...
Frontiers in Genetics 12, 694312, 2021
72021
Moufawad El Achkar, C.; Bhattacharya, S.; Lesca, G.; et al. Heterogeneous clinical and functional features of GRIN2D-related developmental and epileptic encephalopathy
WS XiangWei, V Kannan, YC Xu, GJ Kosobucki, J Anthony, AJ Schulien, ...
Brain 142, 3009-3027, 2019
72019
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated …
W Tang, JT Beckley, J Zhang, R Song, Y Xu, S Kim, MC Quirk, ...
Cellular and Molecular Life Sciences 80 (2), 42, 2023
52023
Imaging Genetics in Epilepsy: Current Knowledge and New Perspectives
G Wang, W Wu, Y Xu, Z Yang, B Xiao, L Long
Frontiers in Molecular Neuroscience 15, 891621, 2022
32022
Clinical and functional consequences of GRIA variants in patients with neurological diseases
W XiangWei, RE Perszyk, N Liu, Y Xu, S Bhattacharya, GH Shaulsky, ...
Cellular and Molecular Life Sciences 80 (11), 345, 2023
12023
Differential responses of disease‐related GRIN variants located in pore‐forming M2 domain of N‐methyl‐D‐aspartate receptor to FDA‐approved inhibitors
R Song, J Zhang, RE Perszyk, CR Camp, W Tang, V Kannan, J Li, Y Xu, ...
Journal of Neurochemistry, 2023
12023
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor
Y Xu, R Song, RE Perszyk, W Chen, S Kim, KL Park, JP Allen, KA Nocilla, ...
Cellular and Molecular Life Sciences 81 (1), 1-25, 2024
2024
The GRIA3 c. 2477G> A variant causes an exaggerated startle reflex, chorea and multifocal myoclonus
W XiangWei, D Amsallem, L Buisson, P Richard, N Liu, Y Xu, M Anheim, ...
2019
Protein-Protein-Interaction Network and Pathway Analysis Related to Alzheimer’s Disease
Y Xu, L Wei, H Li
2018
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