Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers CR Smith, R Aranda, TP Bobinski, DM Briere, AC Burns, JG Christensen, ... Journal of Medicinal Chemistry 65 (3), 1749-1766, 2022 | 65 | 2022 |
Highly efficient, convergent, and enantioselective synthesis of phthioceranic acid S Xu, A Oda, T Bobinski, H Li, Y Matsueda, E Negishi Angewandte Chemie International Edition 54 (32), 9319-9322, 2015 | 37 | 2015 |
KRas G12C inhibitors MA Marx, TP Bobinski, AC Burns, J Gaudino, J Haas, JM Ketcham, ... US Patent 10,647,715, 2020 | 10 | 2020 |
EZH2 inhibitors MA Marx, MR Lee, RA Galemmo, TP Bobinski US Patent 10,266,542, 2019 | 6 | 2019 |
Citric acid mediated catalytic osmylation/oxidative cleavage of electron deficient olefins: A vinyl sulfone study TP Bobinski, PL Fuchs Tetrahedron letters 56 (28), 4151-4154, 2015 | 6 | 2015 |
Kras g12c inhibitors MA Marx, TP Bobinski, AC Burns, J Gaudino, J Haas, JM Ketcham, ... US Patent App. 16/868,258, 2020 | 5 | 2020 |
PRC2 inhibitors MAZ Marx, MR Lee, TP Bobinski, AC Burns, N Arora, JG Christensen, ... WO2019152419A1, 2019 | 4 | 2019 |
Mechanism-specified 5-exo termini differentiation of a C32-desmethyl C28–C34 aplyronine A analog segment TP Bobinski, PL Fuchs Tetrahedron letters 56 (28), 4155-4158, 2015 | 4 | 2015 |
Substituted imidazo [1, 2-c] pyrimidines as PRC2 inhibitors MA Marx, MR Lee, TP Bobinski, AC Burns, N Arora, JG Christensen, ... US Patent 11,485,738, 2022 | 2 | 2022 |
Mta-cooperative prmt5 inhibitors TP BOBINSKI, CR Smith, MA Marx, JM KETCHAM, AC BURNS, ... | 1 | 2022 |
Substituted imidazo [1, 2-c] pyrimidines as PRC2 inhibitors MA Marx, MR Lee, TP Bobinski, AC Burns, N Arora, JG Christensen, ... US Patent 11,220,509, 2022 | 1 | 2022 |
Substituted imidazo [1, 2-c] pyrimidines as PRC2 inhibitors MA Marx, MR Lee, TP Bobinski, AC Burns, N Arora, JG Christensen, ... US Patent 11,091,495, 2021 | 1 | 2021 |
MTA-cooperative PRMT5 inhibitors TP BOBINSKI, CR Smith, MA Marx, JM KETCHAM, AC BURNS, ... | 1 | 2021 |
Triphenylphosphine Dibromide JR Dormoy, B Castro, TP Bobinski Encyclopedia of Reagents for Organic Synthesis, 1-13, 2001 | 1 | 2001 |
Abstract ND04: Discovery of ORIC-944, a novel inhibitor of PRC2 with best-in-class properties for the treatment of prostate cancer MA Marx, AC Burns, N Arora, TP Bobinski, DM Briere, A Calinisan, ... Cancer Research 84 (7_Supplement), ND04-ND04, 2024 | | 2024 |
Substituted isoquinolines as rock kinase inhibitors MR Lee, AJ Varano, TP Bobinski US Patent 11,912,719, 2024 | | 2024 |
SUBSTITUTED IMIDAZO [1, 2-c] PYRIMIDINES AS PRC2 INHIBITORS MA Marx, MR Lee, TP Bobinski, AC Burns, N Arora, JG Christensen, ... US Patent App. 17/822,667, 2023 | | 2023 |
MTA-Cooperative PRMT5 Inhibitors TP Bobinski, CR Smith, MA Marx, JM Ketcham, AC Burns, JD Lawson, ... US Patent App. 17/942,367, 2023 | | 2023 |
Inhibidores prmt5 cooperativos de mta TP Bobinski, CR Smith, MA Marx, JM Ketcham, AC Burns, JD Lawson, ... | | 2023 |
MTA-cooperative PRMT5 inhibitors TP Bobinski, CR Smith, MA Marx, JM Ketcham, AC Burns, JD Lawson, ... US Patent 11,492,351, 2022 | | 2022 |