SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease J Lee, Y Kim, T Liu, YJ Hwang, SJ Hyeon, H Im, K Lee, VE Alvarez, ... Aging cell 17 (1), e12679, 2018 | 173 | 2018 |
Astrocytes and microglia as non-cell autonomous players in the pathogenesis of ALS J Lee, SJ Hyeon, H Im, H Ryu, Y Kim, H Ryu Experimental neurobiology 25 (5), 233, 2016 | 151 | 2016 |
Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport H Choi, HJ Kim, J Kim, S Kim, J Yang, W Lee, Y Park, SJ Hyeon, DS Lee, ... Molecular neurodegeneration 12, 1-14, 2017 | 64 | 2017 |
Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease MY Lee, J Lee, SJ Hyeon, H Cho, YJ Hwang, JY Shin, AC McKee, ... Aging Cell 19 (6), e13153, 2020 | 59 | 2020 |
EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways J Lee, PT Nguyen, HS Shim, SJ Hyeon, H Im, MH Choi, S Chung, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (7 …, 2019 | 57 | 2019 |
A difluoroboron β-diketonate probe shows “turn-on” near-infrared fluorescence specific for tau fibrils K Park, MK Kim, Y Seo, T Ha, K Yoo, SJ Hyeon, YJ Hwang, J Lee, H Ryu, ... ACS chemical neuroscience 8 (10), 2124-2131, 2017 | 53 | 2017 |
Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy JS Seo, S Lee, JY Shin, YJ Hwang, H Cho, SK Yoo, Y Kim, S Lim, YK Kim, ... Experimental & molecular medicine 49 (5), e333-e333, 2017 | 47 | 2017 |
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease YH Ju, M Bhalla, SJ Hyeon, JE Oh, S Yoo, U Chae, J Kwon, W Koh, J Lim, ... Cell Metabolism 34 (8), 1104-1120. e8, 2022 | 46 | 2022 |
Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage YH Bae, H Joo, J Bae, SJ Hyeon, S Her, E Ko, HG Choi, H Ryu, EM Hur, ... Cell death & disease 9 (11), 1125, 2018 | 44 | 2018 |
UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation M Subramanian, SJ Hyeon, T Das, YS Suh, YK Kim, JS Lee, EJ Song, ... Nature communications 12 (1), 3291, 2021 | 42 | 2021 |
“Turn-On” quinoline-based fluorescent probe for selective imaging of tau aggregates in alzheimer’s disease: Rational design, synthesis, and molecular docking AA Elbatrawy, SJ Hyeon, N Yue, EEA Osman, SH Choi, S Lim, YK Kim, ... ACS sensors 6 (6), 2281-2289, 2021 | 30 | 2021 |
Visualization of soluble tau oligomers in TauP301L-BiFC transgenic mice demonstrates the progression of tauopathy S Shin, D Kim, JY Song, H Jeong, SJ Hyeon, NW Kowall, H Ryu, AN Pae, ... Progress in neurobiology 187, 101782, 2020 | 30 | 2020 |
Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington’s disease J Lee, YJ Hwang, Y Kim, MY Lee, SJ Hyeon, S Lee, DH Kim, SJ Jang, ... Acta neuropathologica 134 (5), 729-748, 2017 | 26 | 2017 |
Power failure of mitochondria and oxidative stress in neurodegeneration and its computational models JH Woo, H Cho, YH Seol, SH Kim, C Park, A Yousefian-Jazi, SJ Hyeon, ... Antioxidants 10 (2), 229, 2021 | 20 | 2021 |
Alterations of transcriptome signatures in head trauma-related neurodegenerative disorders H Cho, SJ Hyeon, JY Shin, VE Alvarez, TD Stein, J Lee, NW Kowall, ... Scientific reports 10 (1), 8811, 2020 | 19 | 2020 |
Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDG MH Nam, HY Ko, D Kim, S Lee, YM Park, SJ Hyeon, W Won, JI Chung, ... Brain 146 (7), 2957-2974, 2023 | 17 | 2023 |
Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different Aβ concentrations KC Cap, YJ Jung, BY Choi, SJ Hyeon, JG Kim, JK Min, R Islam, ... Redox biology 32, 101446, 2020 | 17 | 2020 |
L-Citrulline level and transporter activity are altered in experimental models of amyotrophic lateral sclerosis A Gyawali, S Gautam, SJ Hyeon, H Ryu, YS Kang Molecular Neurobiology 58, 647-657, 2021 | 16 | 2021 |
Quantitative proteomic analysis reveals impaired axonal guidance signaling in human postmortem brain tissues of chronic traumatic encephalopathy B Bi, HP Choi, SJ Hyeon, S Sun, N Su, Y Liu, J Lee, NW Kowall, ... Experimental neurobiology 28 (3), 362, 2019 | 15 | 2019 |
Antioxidant and neuroprotective effects of paeonol against oxidative stress and altered carrier-mediated transport system on NSC-34 cell lines S Latif, SH Choi, A Gyawali, SJ Hyeon, YS Kang, H Ryu Antioxidants 11 (7), 1392, 2022 | 11 | 2022 |