A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4414 | 2020 |
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1 S Peng, W Xiao, D Ju, B Sun, N Hou, Q Liu, Y Wang, H Zhao, C Gao, ... Science Translational Medicine 11 (488), eaau7116, 2019 | 226 | 2019 |
A Review of FoxO1-Regulated Metabolic Diseases and Related Drug Discoveries S Peng, W Li, N Hou, N Huang Cells 9 (1), 184, 2020 | 92 | 2020 |
Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors X Lin, XP Huang, G Chen, R Whaley, S Peng, Y Wang, G Zhang, ... Journal of medicinal chemistry 55 (12), 5749-5759, 2012 | 89 | 2012 |
Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes X Chen, B Zhou, J Yan, B Xu, P Tai, J Li, S Peng, M Zhang, G Xia Journal of Endocrinology 197 (2), 409-420, 2008 | 85 | 2008 |
Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer Z Lei, N Chai, M Tian, Y Zhang, G Wang, J Liu, Z Tian, X Yi, D Chen, X Li, ... Cell death & disease 9 (6), 579, 2018 | 37 | 2018 |
Incorporating replacement free energy of binding‐site waters in molecular docking H Sun, L Zhao, S Peng, N Huang Proteins: Structure, Function, and Bioinformatics 82 (9), 1765-1776, 2014 | 34 | 2014 |
Structure-based identification of drug-like inhibitors of p300 histone acetyltransferase. FQ Zeng, SM Peng, L Li, LB Mu, ZH Zhang, ZY Zhang, N Huang Yao xue xue bao= Acta Pharmaceutica Sinica 48 (5), 700-708, 2013 | 20 | 2013 |
Improving the accuracy of pose prediction in molecular docking via structural filtering and conformational clustering SM Peng, Y Zhou, N Huang Chinese Chemical Letters 24 (11), 1001-1004, 2013 | 12 | 2013 |
Identifying multiple-target ligands via computational chemogenomics approaches S Peng, X Lin, Z Guo, N Huang Current Topics in Medicinal Chemistry 12 (12), 1363-1375, 2012 | 9 | 2012 |
Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2 J Yang, Y Xiao, PV Lidsky, CT Wu, LR Bonser, S Peng, MA Garcia-Knight, ... Nature Microbiology 8 (1), 121-134, 2023 | 7 | 2023 |
Entacapone for prevention and treatment of atherosclerosis N Huang, G Zhi, J Chai, S Peng, N Hou US Patent 10,004,715, 2018 | 5 | 2018 |
Entacapone-related compounds to treat macular degeneration N Huang, S Peng US Patent 10,980,766, 2021 | 3 | 2021 |
FTO inhibitors N Huang, S Peng US Patent 10,988,440, 2021 | 1 | 2021 |
Entacapone for treatment of obesity N Huang, G Zhi, J Chai, S Peng, N Hou US Patent 10,682,329, 2020 | 1 | 2020 |