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Killian S Hanlon
Killian S Hanlon
Harvard Medical School
Verified email at hms.harvard.edu
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Cited by
Year
High levels of AAV vector integration into CRISPR-induced DNA breaks
KS Hanlon, BP Kleinstiver, SP Garcia, MP Zaborowski, A Volak, SE Spirig, ...
Nature communications 10 (1), 4439, 2019
3262019
Gene transfer with AAV9-PHP. B rescues hearing in a mouse model of usher syndrome 3A and transduces hair cells in a non-human primate
B György, EJ Meijer, MV Ivanchenko, K Tenneson, F Emond, KS Hanlon, ...
Molecular Therapy-Methods & Clinical Development 13, 1-13, 2019
1372019
Selection of an efficient AAV vector for robust CNS transgene expression
KS Hanlon, JC Meltzer, T Buzhdygan, MJ Cheng, M Sena-Esteves, ...
Molecular Therapy-Methods & Clinical Development 15, 320-332, 2019
1162019
Genomic investigations of unexplained acute hepatitis in children
S Morfopoulou, S Buddle, OE Torres Montaguth, L Atkinson, ...
Nature 617 (7961), 564-573, 2023
712023
AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear
MV Ivanchenko, KS Hanlon, DM Hathaway, AJ Klein, CW Peters, Y Li, ...
Molecular Therapy Methods & Clinical Development 21, 382-398, 2021
462021
Preclinical testing of AAV9-PHP. B for transgene expression in the non-human primate cochlea
MV Ivanchenko*, KS Hanlon*, MK Devine, K Tenneson, F Emond, ...
Hearing Research, 107930, 2020
422020
A novel retinal ganglion cell promoter for utility in AAV vectors
KS Hanlon, N Chadderton, A Palfi, A Blanco Fernandez, P Humphries, ...
Frontiers in Neuroscience 11, 521, 2017
312017
In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery
CB Breuer, KS Hanlon, J Natasan, A Volak, A Meliani, F Mingozzi, ...
Scientific Reports 10 (1), 4544, 2020
252020
Delivering AAV to the central nervous and sensory systems
CW Peters, CA Maguire, KS Hanlon
Trends in pharmacological sciences 42 (6), 461-474, 2021
232021
Versatile Role Of Rab27a In Glioma: Effects On Release Of Extracellular Vesicles, Cell Viability And Tumor Progression
TS Van Solinge, ER Abels, LL Van De Haar, KS Hanlon, SLN Maas, ...
Frontiers in molecular biosciences 7, 324, 2020
152020
The AAV9 variant capsid AAV-F mediates widespread transgene expression in nonhuman primate spinal cord after intrathecal administration
A Beharry, Y Gong, JC Kim, KS Hanlon, J Nammour, K Hieber, F Eichler, ...
Human Gene Therapy 33 (1-2), 61-75, 2022
142022
Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells
S Millington-Ward, N Chadderton, M Berkeley, LK Finnegan, KS Hanlon, ...
Scientific Reports 10 (1), 16515, 2020
102020
Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F
CW Peters, KS Hanlon, MV Ivanchenko, E Zinn, EF Linarte, Y Li, JM Levy, ...
Molecular Therapy 31 (8), 2439-2453, 2023
92023
An engineered adeno-associated virus capsid mediates efficient transduction of pericytes and smooth muscle cells of the brain vasculature
SH Ramirez, JF Hale, S McCarthy, CL Lino Cardenas, KNUG Dona, ...
Human Gene Therapy 34 (15-16), 682-696, 2023
32023
Optimisation of AAV-NDI1 Significantly Enhances Its Therapeutic Value for Correcting Retinal Mitochondrial Dysfunction
N Chadderton, A Palfi, DM Maloney, M Carrigan, LK Finnegan, ...
Pharmaceutics 15 (2), 322, 2023
22023
Optimisation of Therapies for Inherited Retinal and Mitochondrial Diseases
K Hanlon
Trinity College Dublin, 2018
12018
In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord
KS Hanlon, M Cheng, RM Ferrer, JR Ryu, B Lee, D De La Cruz, N Patel, ...
Molecular Therapy, 2024
2024
In vivo selection in non-human primates identifies superior AAV capsids for on-target CSF delivery to spinal cord
KS Hanlon, M Cheng, D De La Cruz, N Patel, MC Santoscoy, Y Gong, ...
bioRxiv, 2023
2023
Amelioration of retinal mitochondrial dysfunction with AAV-ophNdi1
N Chadderton, A Palfi, DM Maloney, MA Carrigan, LK Finnegan, ...
HUMAN GENE THERAPY 33 (23-24), A90-A91, 2022
2022
Engineered adeno-associated (aav) vectors for transgene expression
CA Maguire, EM Hudry, KS Hanlon
US Patent App. 17/442,894, 2022
2022
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