Gene therapy for chronic HBV—can we eliminate cccDNA? K Bloom, MB Maepa, A Ely, P Arbuthnot Genes 9 (4), 207, 2018 | 83 | 2018 |
ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells T Scott, B Moyo, S Nicholson, MB Maepa, K Watashi, A Ely, MS Weinberg, ... Scientific reports 7 (1), 7401, 2017 | 68 | 2017 |
Function and regulation of class I ribonucleotide reductase-encoding genes in mycobacteria MB Mowa, DF Warner, G Kaplan, BD Kana, V Mizrahi Journal of bacteriology 191 (3), 985-995, 2009 | 68 | 2009 |
Advances with RNAi-based therapy for hepatitis B virus infection F van Den Berg, SW Limani, N Mnyandu, MB Maepa, A Ely, P Arbuthnot Viruses 12 (8), 851, 2020 | 58 | 2020 |
Progress and prospects of anti-HBV gene therapy development MB Maepa, I Roelofse, A Ely, P Arbuthnot International Journal of Molecular Sciences 16 (8), 17589-17610, 2015 | 52 | 2015 |
Therapeutic potential of adenoviral vectors for delivery of expressed RNAi activators MB Mowa, C Crowther, P Arbuthnot Expert opinion on drug delivery 7 (12), 1373-1385, 2010 | 47 | 2010 |
Inhibition of Hepatitis B virus replication by helper dependent adenoviral vectors expressing artificial anti‐HBV Pri‐miRs from a liver‐specific promoter MB Mowa, C Crowther, A Ely, P Arbuthnot BioMed research international 2014 (1), 718743, 2014 | 34 | 2014 |
Sustained inhibition of HBV replication in vivo after systemic injection of AAVs encoding artificial antiviral primary microRNAs MB Maepa, A Ely, W Grayson, P Arbuthnot Molecular Therapy-Nucleic Acids 7, 190-199, 2017 | 25 | 2017 |
Inhibition of HBV replication in vivo using helper-dependent adenovirus vectors to deliver antiviral RNA interference expression cassettes C Crowther, MB Mowa, A Ely, PB Arbuthnot Antiviral therapy 19 (4), 363-373, 2014 | 20 | 2014 |
Hepatitis B virus research in South Africa MB Maepa, A Ely, A Kramvis, K Bloom, K Naidoo, OE Simani, ... Viruses 14 (9), 1939, 2022 | 14 | 2022 |
The state of gene therapy research in Africa, its significance and implications for the future P Arbuthnot, MB Maepa, A Ely, MS Pepper Gene Therapy 24 (9), 581-589, 2017 | 14 | 2017 |
Efficient silencing of hepatitis B virus replication by helper-dependent adenovirus vector-mediated delivery of artificial antiviral primary micro RNAs MB Mowa, C Crowther, A Ely, P Arbuthnot Micro RNA 2012 (1), 19-25, 2012 | 11* | 2012 |
Recent update on the role of circular RNAs in hepatocellular carcinoma A Ely, K Bloom, MB Maepa, P Arbuthnot Journal of Hepatocellular Carcinoma, 1-17, 2021 | 10 | 2021 |
Recent developments with advancing gene therapy to treat chronic infection with hepatitis B virus MB Maepa, R Jacobs, F van den Berg, P Arbuthnot Current Opinion in HIV and AIDS 15 (3), 200-207, 2020 | 8 | 2020 |
Hepatic delivery of artificial micro RNAs using helper-dependent adenoviral vectors C Crowther, B Mowa, P Arbuthnot SiRNA delivery methods: methods and protocols, 249-260, 2016 | 7 | 2016 |
Adenoviral vectors: potential as anti-HBV vaccines and therapeutics T Farhad, K Neves, P Arbuthnot, MB Maepa Genes 13 (11), 1941, 2022 | 6 | 2022 |
Hepatitis B virus: promising drug targets and therapeutic implications MB Maepa, K Bloom, A Ely, P Arbuthnot Expert Opinion on Therapeutic Targets 25 (6), 451-466, 2021 | 6 | 2021 |
Advances in designing Adeno-associated viral vectors for development of anti-HBV gene therapeutics N Mnyandu, SW Limani, P Arbuthnot, MB Maepa Virology Journal 18 (1), 247, 2021 | 5 | 2021 |
In vivo delivery of cassettes encoding anti-hbv primary micrornas using an ancestral adeno-associated viral vector N Mnyandu, P Arbuthnot, MB Maepa RNA Interference and CRISPR Technologies: Technical Advances and New …, 2020 | 5 | 2020 |
Gene and cell therapy in South Africa: current status and future prospects A Ely, K Bloom, MB Maepa, JN Mahlangu, MS Pepper, P Arbuthnot South African Medical Journal 109 (8 Supplement 1), S13-S17, 2019 | 4 | 2019 |