A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ... Cell stem cell 27 (1), 125-136. e7, 2020 | 658 | 2020 |
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, ... Nature 589 (7841), 270-275, 2021 | 470 | 2021 |
SARS-CoV-2 infection induces beta cell transdifferentiation X Tang, S Uhl, T Zhang, D Xue, B Li, JJ Vandana, JA Acklin, ... Cell metabolism 33 (8), 1577-1591. e7, 2021 | 162 | 2021 |
Identification of candidate COVID-19 therapeutics using hPSC-derived lung organoids Y Han, L Yang, X Duan, F Duan, BE Nilsson-Payant, TM Yaron, P Wang, ... BioRxiv, 2020 | 104 | 2020 |
TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy C Wang, X Tang, X Sun, Z Miao, Y Lv, Y Yang, H Zhang, P Zhang, Y Liu, ... Cell research 22 (1), 194-207, 2012 | 101 | 2012 |
Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons S Li, Q He, H Wang, X Tang, KW Ho, X Gao, Q Zhang, Y Shen, A Cheung, ... Neurobiology of disease 73, 366-376, 2015 | 61 | 2015 |
RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression XY Ming, X Zhang, TT Cao, LY Zhang, JL Qi, NW Kam, XM Tang, YZ Cui, ... Theranostics 8 (1), 185, 2018 | 41 | 2018 |
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection X Duan, X Tang, MS Nair, T Zhang, Y Qiu, W Zhang, P Wang, Y Huang, ... Cell reports 37 (6), 2021 | 39 | 2021 |
Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells TT Cao, SH Lin, L Fu, Z Tang, CM Che, LY Zhang, XY Ming, TF Liu, ... Carcinogenesis 38 (1), 94-104, 2017 | 30 | 2017 |
PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway Tang, X., Cao, T., Zhu, Y. Zhang, L., Chen, J., Liu, T., Ming, X., Fang, S ... Cell Death Dis 11 (510), 2020 | 22 | 2020 |
A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection X Tang, D Xue, T Zhang, BE Nilsson-Payant, L Carrau, X Duan, ... Nature Cell Biology 25 (3), 381-389, 2023 | 8 | 2023 |
A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating YX Ni, N Zhou, WQ Xue, L Rong, WH Yung, RZ Lin, RYT Kao, ZG Duan, ... Cell Discovery 4 (1), 65, 2018 | 6 | 2018 |
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells D Xue, N Narisu, DL Taylor, M Zhang, C Grenko, HJ Taylor, T Yan, X Tang, ... Cell Metabolism 35 (11), 1897-1914. e11, 2023 | 3 | 2023 |
Single-cell gene expression and chromatin accessibility profiling of human pancreatic islets at basal and stimulatory conditions nominates mechanisms of type 1 diabetes genetic … RDO Albanus, X Tang, HJ Taylor, N Manickam, M Erdos, N Narisu, Y Han, ... bioRxiv, 2022.11. 12.516291, 2022 | 3 | 2022 |
An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals Z Zhao, RDO Albanus, H Taylor, X Tang, Y Han, P Orchard, A Varshney, ... Research Square, 2023 | 1 | 2023 |
Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits S Hudaiberdiev, DL Taylor, W Song, N Narisu, RM Bhuiyan, HJ Taylor, ... Proceedings of the National Academy of Sciences 120 (35), e2206612120, 2023 | 1 | 2023 |
Functional interrogation of twenty type 2 diabetes associated genes using isogenic hESC-derived β-like cells D Xue, N Narisu, DL Taylor, M Zhang, C Grenko, HJ Taylor, T Yan, X Tang, ... bioRxiv, 2023.05. 07.539774, 2023 | 1 | 2023 |
The role of tumor microenvironment in the development, treatment and prognosis of hepatocellular carcinoma H Wang, H Liu, X Tang, J Chen, Z Ren Frontiers in Pharmacology 14, 1343175, 2024 | | 2024 |
283-OR: ADA Presidents' Select Abstract: An Isogenic hPSC-Based Platform for Functional Interrogation of the Role of Multiple T2D-Associated Genes in Pancreatic Beta-Cell Failure D XUE, N NARISU, T YAN, M ZHANG, C GRENKO, X TANG, J ZHU, ... Diabetes 72 (Supplement_1), 2023 | | 2023 |
Role of anterograde motor Kif5b in clathrin-coated vesicle uncoating and clathrin-mediated endocytosis YX Ni, WQ Xue, N Zhou, WH Yung, RZ Lin, RYT Kao, ZG Duan, XM Tang, ... bioRxiv, 284166, 2018 | | 2018 |