| Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa Y Meng, W Tang, Y Dai, X Wu, M Liu, Q Ji, M Ji, K Pienta, T Lawrence, ... Molecular cancer therapeutics 7 (7), 2192-2202, 2008 | 225 | 2008 |
| A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum J Lian, X Wu, F He, D Karnak, W Tang, Y Meng, D Xiang, M Ji, ... Cell Death & Differentiation 18 (1), 60-71, 2011 | 194 | 2011 |
| Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction XL Wu X, Lan L, Wilson DM, Marquez RT, Tsao WC, Gao P, Roy A, Turner B.A ... ACS Chem Biol 10 (6), 1476-1484, 2015 | 149 | 2015 |
| Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1 L Lan, C Appelman, AR Smith, J Yu, S Larsen, RT Marquez, H Liu, X Wu, ... Molecular oncology 9 (7), 1406-1420, 2015 | 131 | 2015 |
| Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents J Cai, M Sun, X Wu, J Chen, P Wang, X Zong, M Ji European Journal of Medicinal Chemistry 63, 702-712, 2013 | 95 | 2013 |
| Molecular and functional extracellular vesicle analysis using nanopatterned microchips monitors tumor progression and metastasis P Zhang, X Wu, G Gardashova, Y Yang, Y Zhang, L Xu, Y Zeng Science translational medicine 12 (547), eaaz2878, 2020 | 85 | 2020 |
| Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis X Wu, G Gardashova, L Lan, S Han, C Zhong, RT Marquez, L Wei, ... Communications biology 3 (1), 193, 2020 | 74 | 2020 |
| Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling X Wu, W Tang, RT Marquez, K Li, CA Highfill, F He, J Lian, J Lin, ... Oncotarget 7 (10), 11708, 2016 | 71 | 2016 |
| Design and synthesis of novel Gefitinib analogues with improved anti-tumor activity X Wu, M Li, Y Qu, W Tang, Y Zheng, J Lian, M Ji, L Xu Bioorganic & medicinal chemistry 18 (11), 3812-3822, 2010 | 71 | 2010 |
| HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s L Li, W Tang, X Wu, D Karnak, X Meng, R Thompson, X Hao, Y Li, ... Clinical Cancer Research 19 (24), 6703-6715, 2013 | 66 | 2013 |
| Design, synthesis, and in vitro antitumor evaluation of novel diaryl ureas derivatives M Sun, X Wu, J Chen, J Cai, M Cao, M Ji European journal of medicinal chemistry 45 (6), 2299-2306, 2010 | 63 | 2010 |
| Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors JM Cai J, Wei H, Hong KH, Wu X, Cao M, Zong X, Li L, Sun C, Chen J Eur J Med Chem 96, 1-13, 2015 | 62 | 2015 |
| The RNA-binding protein HuR in human cancer: A friend or foe? X Wu, L Xu Advanced drug delivery reviews 184, 114179, 2022 | 48 | 2022 |
| The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro K Kaur, X Wu, JK Fields, DK Johnson, L Lan, M Pratt, AD Somoza, ... PLoS One 12 (4), e0175471, 2017 | 48 | 2017 |
| Human antigen R as a therapeutic target in pathological cardiac hypertrophy LC Green, SR Anthony, S Slone, L Lanzillotta, ML Nieman, X Wu, ... JCI insight 4 (4), 2019 | 47 | 2019 |
| Activation of HuR downstream of p38 MAPK promotes cardiomyocyte hypertrophy S Slone, SR Anthony, X Wu, JB Benoit, J Aube, L Xu, M Tranter Cellular signalling 28 (11), 1735-1741, 2016 | 46 | 2016 |
| An RNA-binding protein, Hu-antigen R, in pancreatic cancer epithelial to mesenchymal transition, metastasis, and cancer stem cells R Dong, P Chen, K Polireddy, X Wu, T Wang, R Ramesh, DA Dixon, L Xu, ... Molecular cancer therapeutics 19 (11), 2267-2277, 2020 | 44 | 2020 |
| Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins L Lan, H Liu, AR Smith, C Appelman, J Yu, S Larsen, RT Marquez, X Wu, ... BMC cancer 18, 1-14, 2018 | 42 | 2018 |
| Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents. JM Cai J, Wei H, Hong KH, Wu X, Zong X, Cao M, Wang P, Li L, Sun C, Chen B ... Bioorg Med Chem 23 (13), 3457-3471, 2015 | 36 | 2015 |
| MicroRNA‐383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression J Li, AR Smith, RT Marquez, J Li, K Li, L Lan, X Wu, L Zhao, F Ren, ... Molecular carcinogenesis 57 (10), 1408-1420, 2018 | 33 | 2018 |
Liang Xu, M.D., Ph.D.Professor, University of KansasVerified email at ku.edu
