| The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology J Trebicka, J Fernandez, M Papp, P Caraceni, W Laleman, C Gambino, ... Journal of hepatology 73 (4), 842-854, 2020 | 337 | 2020 |
| FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis L Verbeke, I Mannaerts, R Schierwagen, O Govaere, S Klein, ... Scientific reports 6 (1), 1-12, 2016 | 202 | 2016 |
| PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis J Trebicka, J Fernandez, M Papp, P Caraceni, W Laleman, C Gambino, ... Journal of hepatology 74 (5), 1097-1108, 2021 | 186 | 2021 |
| Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis R Schierwagen, L Maybüchen, S Zimmer, K Hittatiya, C Bäck, S Klein, ... Scientific reports 5 (1), 12931, 2015 | 179 | 2015 |
| Addressing profiles of systemic inflammation across the different clinical phenotypes of acutely decompensated cirrhosis J Trebicka, A Amoros, C Pitarch, E Titos, J Alcaraz-Quiles, R Schierwagen, ... Frontiers in immunology 10, 476, 2019 | 157 | 2019 |
| Angiotensin‐II type 1 receptor‐mediated Janus kinase 2 activation induces liver fibrosis M Granzow, R Schierwagen, S Klein, B Kowallick, S Huss, M Linhart, ... Hepatology 60 (1), 334-348, 2014 | 142 | 2014 |
| Circulating microbiome in blood of different circulatory compartments R Schierwagen, C Alvarez-Silva, MSA Madsen, CC Kolbe, C Meyer, ... Gut 68 (3), 578-580, 2019 | 133 | 2019 |
| A faecal microbiota signature with high specificity for pancreatic cancer E Kartal, TSB Schmidt, E Molina-Montes, S Rodríguez-Perales, J Wirbel, ... Gut 71 (7), 1359-1372, 2022 | 126 | 2022 |
| Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats S Klein, J Klösel, R Schierwagen, C Körner, M Granzow, S Huss, ... Laboratory investigation 92 (10), 1440-1450, 2012 | 119 | 2012 |
| Quantification of liver fibrosis at T1 and T2 mapping with extracellular volume fraction MRI: preclinical results JA Luetkens, S Klein, F Träber, FC Schmeel, AM Sprinkart, DLR Kuetting, ... Radiology 288 (3), 748-754, 2018 | 118 | 2018 |
| Activation of the Mas receptor by angiotensin-(1–7) in the renin–angiotensin system mediates mesenteric vasodilatation in cirrhosis JA Grace, S Klein, CB Herath, M Granzow, R Schierwagen, N Masing, ... Gastroenterology 145 (4), 874-884. e5, 2013 | 111 | 2013 |
| HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects S Klein, MM Van Beuge, M Granzow, L Beljaars, R Schierwagen, S Kilic, ... Journal of hepatology 57 (6), 1220-1227, 2012 | 110 | 2012 |
| Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor‐deficient mice and decreased in CB1 receptor … J Trebicka, I Racz, SV Siegmund, E Cara, M Granzow, R Schierwagen, ... Liver International 31 (6), 860-870, 2011 | 102 | 2011 |
| Total area of spontaneous portosystemic shunts independently predicts hepatic encephalopathy and mortality in liver cirrhosis M Praktiknjo, M Simón-Talero, J Römer, D Roccarina, J Martínez, ... Journal of hepatology 72 (6), 1140-1150, 2020 | 98 | 2020 |
| Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality C Jansen, P Möller, C Meyer, CC Kolbe, C Bogs, A Pohlmann, ... Hepatology 67 (4), 1472-1484, 2018 | 85 | 2018 |
| Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment KM Schneider, A Mohs, W Gui, EJC Galvez, LS Candels, L Hoenicke, ... Nature Communications 13 (1), 3964, 2022 | 78 | 2022 |
| Tumor-necrosis factor impairs CD4+ T cell–mediated immunological control in chronic viral infection M Beyer, Z Abdullah, JM Chemnitz, D Maisel, J Sander, C Lehmann, ... Nature immunology 17 (5), 593-603, 2016 | 77 | 2016 |
| Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation S Monteiro, J Grandt, FE Uschner, N Kimer, JL Madsen, R Schierwagen, ... Gut 70 (2), 379-387, 2021 | 75 | 2021 |
| Statins improve NASH via inhibition of RhoA and Ras R Schierwagen, L Maybüchen, K Hittatiya, S Klein, FE Uschner, TT Braga, ... American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016 | 74 | 2016 |
| Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis S Klein, J Rick, J Lehmann, R Schierwagen, IG Schierwagen, L Verbeke, ... Gut 66 (1), 145-155, 2017 | 71 | 2017 |
Jonel TrebickaProfessor, University of MünsterVerified email at ukmuenster.de
