Mini review: Genome mining approaches for the identification of secondary metabolite biosynthetic gene clusters in Streptomyces N Lee, S Hwang, J Kim, S Cho, B Palsson, BK Cho Computational and Structural Biotechnology Journal 18, 1548-1556, 2020 | 137 | 2020 |
Thirty complete Streptomyces genome sequences for mining novel secondary metabolite biosynthetic gene clusters N Lee, W Kim, S Hwang, Y Lee, S Cho, B Palsson, BK Cho Scientific data 7 (1), 55, 2020 | 94 | 2020 |
Iron competition triggers antibiotic biosynthesis in Streptomyces coelicolor during coculture with Myxococcus xanthus N Lee, W Kim, J Chung, Y Lee, S Cho, KS Jang, SC Kim, B Palsson, ... The ISME journal 14 (5), 1111-1124, 2020 | 84 | 2020 |
Synthetic biology tools for novel secondary metabolite discovery in Streptomyces N Lee, S Hwang, Y Lee, S Cho, B Palsson, BK Cho Korean Society for Microbiology and Biotechnology 29 (5), 667-686, 2019 | 84 | 2019 |
Ageing and rejuvenation models reveal changes in key microbial communities associated with healthy ageing J Shin, JR Noh, D Choe, N Lee, Y Song, S Cho, EJ Kang, MJ Go, SK Ha, ... Microbiome 9, 1-19, 2021 | 58 | 2021 |
Primary transcriptome and translatome analysis determines transcriptional and translational regulatory elements encoded in the Streptomyces clavuligerus genome S Hwang, N Lee, Y Jeong, Y Lee, W Kim, S Cho, BO Palsson, BK Cho Nucleic acids research 47 (12), 6114-6129, 2019 | 51 | 2019 |
Repurposing modular polyketide synthases and non-ribosomal peptide synthetases for novel chemical biosynthesis S Hwang, N Lee, S Cho, B Palsson, BK Cho Frontiers in molecular biosciences 7, 87, 2020 | 42 | 2020 |
Systems and synthetic biology to elucidate secondary metabolite biosynthetic gene clusters encoded in Streptomyces genomes N Lee, S Hwang, W Kim, Y Lee, JH Kim, S Cho, HU Kim, YJ Yoon, MK Oh, ... Natural Product Reports 38 (7), 1330-1361, 2021 | 41 | 2021 |
Discovery of novel secondary metabolites encoded in actinomycete genomes through coculture JH Kim, N Lee, S Hwang, W Kim, Y Lee, S Cho, BO Palsson, BK Cho Journal of Industrial Microbiology and Biotechnology 48 (3-4), kuaa001, 2021 | 38 | 2021 |
Targeted gene deletion using DNA-free RNA-guided Cas9 nuclease accelerates adaptation of CHO cells to suspension culture N Lee, JO Shin, JH Park, GM Lee, S Cho, BK Cho ACS synthetic biology 5 (11), 1211-1219, 2016 | 37 | 2016 |
The Transcription Unit Architecture of Streptomyces lividans TK24 Y Lee, N Lee, Y Jeong, S Hwang, W Kim, S Cho, BO Palsson, BK Cho Frontiers in Microbiology 10, 2074, 2019 | 33 | 2019 |
Transcriptome and translatome profiles of Streptomyces species in different growth phases W Kim, S Hwang, N Lee, Y Lee, S Cho, B Palsson, BK Cho Scientific data 7 (1), 138, 2020 | 22 | 2020 |
Efficient CRISPR/Cas9-mediated multiplex genome editing in CHO cells via high-level sgRNA-Cas9 complex J Shin, N Lee, Y Song, J Park, TJ Kang, SC Kim, GM Lee, BK Cho Biotechnology and bioprocess engineering 20, 825-833, 2015 | 22 | 2015 |
Improved production of clavulanic acid by reverse engineering and overexpression of the regulatory genes in an industrial Streptomyces clavuligerus strain HS Cho, JC Jo, CH Shin, N Lee, JS Choi, BK Cho, JH Roe, CW Kim, ... Journal of Industrial Microbiology and Biotechnology 46 (8), 1205-1215, 2019 | 15 | 2019 |
Comparative Genomics Determines Strain-Dependent Secondary Metabolite Production in Streptomyces venezuelae Strains W Kim, N Lee, S Hwang, Y Lee, J Kim, S Cho, B Palsson, BK Cho Biomolecules 10 (6), 864, 2020 | 14 | 2020 |
System-level understanding of gene expression and regulation for engineering secondary metabolite production in Streptomyces Y Lee, N Lee, S Hwang, K Kim, W Kim, J Kim, S Cho, BO Palsson, BK Cho Journal of Industrial Microbiology & Biotechnology: Official Journal of the …, 2020 | 12 | 2020 |
Targeted genome editing using DNA-free RNA-guided Cas9 ribonucleoprotein for CHO cell engineering J Shin, N Lee, S Cho, BK Cho Synthetic Biology: Methods and Protocols, 151-169, 2018 | 9 | 2018 |
Thirty complete Streptomyces genome sequences for mining novel secondary metabolite biosynthetic gene clusters. Sci Data. 2020; 7 (1): 55 N Lee, W Kim, S Hwang, Y Lee, S Cho, B Palsson | 8 | |
Maximizing heterologous expression of engineered type I polyketide synthases: Investigating codon optimization strategies M Schmidt, N Lee, C Zhan, JB Roberts, AA Nava, LS Keiser, AA Vilchez, ... ACS Synthetic Biology 12 (11), 3366-3380, 2023 | 7 | 2023 |
Genome-scale determination of 5´ and 3´ boundaries of RNA transcripts in Streptomyces genomes Y Lee, N Lee, S Hwang, W Kim, Y Jeong, S Cho, BO Palsson, BK Cho Scientific data 7 (1), 436, 2020 | 7 | 2020 |