| α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, ... Nature communications 9 (1), 2293, 2018 | 413 | 2018 |
| Ultrarapid generation of femtoliter microfluidic droplets for single-molecule-counting immunoassays J Shim, RT Ranasinghe, CA Smith, SM Ibrahim, F Hollfelder, WTS Huck, ... ACS nano 7 (7), 5955-5964, 2013 | 248 | 2013 |
| Single-molecule visualization of DNA G-quadruplex formation in live cells M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, ... Nature chemistry 12 (9), 832-837, 2020 | 246 | 2020 |
| Fluorescence based strategies for genetic analysis RT Ranasinghe, T Brown Chemical Communications, 5487-5502, 2005 | 198 | 2005 |
| Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, ... Nature communications 7 (1), 13544, 2016 | 184 | 2016 |
| Four base recognition by triplex-forming oligonucleotides at physiological pH DA Rusling, VEC Powers, RT Ranasinghe, Y Wang, SD Osborne, ... Nucleic acids research 33 (9), 3025-3032, 2005 | 149 | 2005 |
| Naphthalenyl-and anthracenyl-ethynyl dT analogues as base discriminating fluorescent nucleosides and intramolecular energy transfer donors in oligonucleotide probes Q Xiao, RT Ranasinghe, AMP Tang, T Brown Tetrahedron 63 (17), 3483-3490, 2007 | 77 | 2007 |
| Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease D Emin, YP Zhang, E Lobanova, A Miller, X Li, Z Xia, H Dakin, DI Sideris, ... Nature communications 13 (1), 5512, 2022 | 69 | 2022 |
| Ultrasensitive fluorescence-based methods for nucleic acid detection: towards amplification-free genetic analysis RT Ranasinghe, T Brown Chemical communications 47 (13), 3717-3735, 2011 | 65 | 2011 |
| Nanoscopic characterisation of individual endogenous protein aggregates in human neuronal cells DR Whiten, Y Zuo, L Calo, ML Choi, S De, P Flagmeier, DC Wirthensohn, ... ChemBioChem 19 (19), 2033-2038, 2018 | 56 | 2018 |
| Single‐Molecule Imaging Reveals that Small Amyloid‐β1–42 Oligomers Interact with the Cellular Prion Protein (PrPC) KA Ganzinger, P Narayan, SS Qamar, L Weimann, RT Ranasinghe, ... Chembiochem 15 (17), 2515-2521, 2014 | 49 | 2014 |
| Recognition of CG inversions in DNA triple helices by methylated 3 H-pyrrolo [2, 3-d] pyrimidin-2 (7 H)-one nucleoside analogues RT Ranasinghe, DA Rusling, VEC Powers, KR Fox, T Brown Chemical communications, 2555-2557, 2005 | 39 | 2005 |
| Single molecule fluorescence under conditions of fast flow MH Horrocks, H Li, J Shim, RT Ranasinghe, RW Clarke, WTS Huck, ... Analytical chemistry 84 (1), 179-185, 2012 | 38 | 2012 |
| Multistep synthesis on SU-8: combining microfabrication and solid-phase chemistry on a single material G Cavalli, S Banu, RT Ranasinghe, GR Broder, HFP Martins, C Neylon, ... Journal of combinatorial chemistry 9 (3), 462-472, 2007 | 37 | 2007 |
| Diffractive micro bar codes for encoding of biomolecules in multiplexed assays GR Broder, RT Ranasinghe, JK She, S Banu, SW Birtwell, G Cavalli, ... Analytical chemistry 80 (6), 1902-1909, 2008 | 35 | 2008 |
| Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation RT Ranasinghe, LJ Brown, T Brown Chemical Communications, 1480-1481, 2001 | 31 | 2001 |
| Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells JC Sang, E Hidari, G Meisl, RT Ranasinghe, MG Spillantini, D Klenerman Communications biology 4 (1), 613, 2021 | 28 | 2021 |
| Detecting RNA base methylations in single cells by in situ hybridization RT Ranasinghe, MR Challand, KA Ganzinger, BW Lewis, C Softley, ... Nature Communications 9 (1), 655, 2018 | 28 | 2018 |
| Highly rapid amplification-free and quantitative DNA imaging assay T Klamp, M Camps, B Nieto, F Guasch, RT Ranasinghe, J Wiedemann, ... Scientific reports 3 (1), 1852, 2013 | 26 | 2013 |
| Kinetics and thermodynamics of biotinylated oligonucleotide probe binding to particle-immobilized avidin and implications for multiplexing applications GR Broder, RT Ranasinghe, C Neylon, H Morgan, PL Roach Analytical chemistry 83 (6), 2005-2011, 2011 | 19 | 2011 |
Mathew HorrocksSenior Lecturer in Biophysics, School of Chemistry, University of EdinburghVerified email at ed.ac.uk
