| A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1 C De Nardis, LJA Hendriks, E Poirier, T Arvinte, P Gros, ABH Bakker, ... Journal of Biological Chemistry 292 (35), 14706-14717, 2017 | 92 | 2017 |
| Unbiased combinatorial screening identifies a bispecific IgG1 that potently inhibits HER3 signaling via HER2-guided ligand blockade CAW Geuijen, C De Nardis, D Maussang, E Rovers, T Gallenne, ... Cancer Cell 33 (5), 922-936. e10, 2018 | 91 | 2018 |
| Recombinant expression of the full-length ectodomain of LDL receptor-related protein 1 (LRP1) unravels pH-dependent conformational changes and the stoichiometry of binding with … C De Nardis, P Lössl, M Van Den Biggelaar, PK Madoori, N Leloup, ... Journal of Biological Chemistry 292 (3), 912-924, 2017 | 21 | 2017 |
| Complement C1q interacts with LRP1 clusters ii and iv through a site close but different from the binding site of Its C1r and C1s-associated proteases G Fouët, E Gout, C Wicker-Planquart, I Bally, C De Nardis, S Dedieu, ... Frontiers in Immunology 11, 583754, 2020 | 6 | 2020 |
| The binding mode of the bispecific anti-HER2xHER3 antibody MCLA-128 is responsible for its potent inhibition of HRG-driven tumorigenesis D Maussang-Detaille, C Nardis, L Hendriks, C Bartelink-Clements, ... Cancer Research 77 (13_Supplement), 33-33, 2017 | 4 | 2017 |
| Unbiased combinatorial screening identifies a bispecific IgG1 that potently inhibits HER3 signaling via HER2-guided ligand blockade CAW Geuijen, C De Nardis, D Maussang, E Rovers, T Gallenne, ... Cancer Cell 39 (8), 1163-1164, 2021 | 3 | 2021 |
| Structural studies of human cell surface receptors: On low-density lipoprotein receptor-related protein 1 and epidermal growth factor receptors 2 and 3 C De Nardis Utrecht University, 2017 | | 2017 |
| Application of unbiased combinatorial screening to generate a bispecific IgG1 that selectively and potently inhibits HER3 signaling via HER2-guided ligand blockade C Geuijen, C De Nardis, D Maussang, E Rovers, T Gallenne, ... Structural studies of human cell surface receptors, 57, 2017 | | 2017 |
| Mass Spectrometry Reaching Out to Complementary Structural Biology Approaches P Lössl, C De Nardis, J Snijder, JM Schuller Integrative Mass Spectrometry Approaches to Monitor Protein Structures …, 2017 | | 2017 |
