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Paul Kostenuik
Paul Kostenuik
Phylon Pharma Services, University of Michigan
在 PhylonPS.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
J Li, I Sarosi, XQ Yan, S Morony, C Capparelli, HL Tan, S McCabe, ...
Proceedings of the national academy of sciences 97 (4), 1566-1571, 2000
14102000
Receptor activator of nuclear factor κB ligand and osteoprotegerin regulation of bone remodeling in health and disease
AE Kearns, S Khosla, PJ Kostenuik
Endocrine reviews 29 (2), 155-192, 2008
11102008
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
X Li, MS Ominsky, QT Niu, N Sun, B Daugherty, D D'Agostin, C Kurahara, ...
Journal of Bone and Mineral Research 23 (6), 860-869, 2008
11062008
Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
X Li, MS Ominsky, KS Warmington, S Morony, J Gong, J Cao, Y Gao, ...
Journal of Bone and Mineral Research 24 (4), 578-588, 2009
9552009
Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis
H Min, S Morony, I Sarosi, CR Dunstan, C Capparelli, S Scully, G Van, ...
The Journal of experimental medicine 192 (4), 463-474, 2000
7942000
Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab
DL Lacey, WJ Boyle, WS Simonet, PJ Kostenuik, WC Dougall, JK Sullivan, ...
Nature reviews Drug discovery 11 (5), 401-419, 2012
7402012
Growth factor regulation of fracture repair
GL Barnes, PJ Kostenuik, LC Gerstenfeld, TA Einhorn
Journal of bone and mineral research 14 (11), 1805-1815, 1999
7201999
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
J Li, I Sarosi, RC Cattley, J Pretorius, F Asuncion, M Grisanti, S Morony, ...
Bone 39 (4), 754-766, 2006
5442006
Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knockin mice that express chimeric (murine/human) RANKL
PJ Kostenuik, HQ Nguyen, J McCabe, KS Warmington, C Kurahara, ...
Journal of Bone and Mineral Research 24 (2), 182-195, 2009
5022009
Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strength
PJ Kostenuik
Current opinion in pharmacology 5 (6), 618-625, 2005
4362005
Osteoprotegerin A Physiological and Pharmacological Inhibitor of Bone Resorption.
PJ Kostenuik
Current pharmaceutical design 7 (8), 613-635, 2001
3682001
Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis
S Morony, C Capparelli, I Sarosi, DL Lacey, CR Dunstan, PJ Kostenuik
Cancer research 61 (11), 4432-4436, 2001
3592001
Osteoprotegerin Inhibits Vascular Calcification Without Affecting Atherosclerosis in ldlr(−/−) Mice
S Morony, Y Tintut, Z Zhang, RC Cattley, G Van, D Dwyer, M Stolina, ...
Circulation 117 (3), 411-420, 2008
3492008
Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats
X Li, KS Warmington, QT Niu, FJ Asuncion, M Barrero, M Grisanti, ...
Journal of Bone and Mineral Research 25 (12), 2647-2656, 2010
2852010
Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing
LC Gerstenfeld, DJ Sacks, M Pelis, ZD Mason, DT Graves, M Barrero, ...
Journal of bone and mineral research 24 (2), 196-208, 2009
2752009
Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women
MT Drake, B Srinivasan, UI Mödder, JM Peterson, LK McCready, ...
The Journal of Clinical Endocrinology & Metabolism 95 (11), 5056-5062, 2010
2632010
Effects of spaceflight on murine skeletal muscle gene expression
DL Allen, ER Bandstra, BC Harrison, S Thorng, LS Stodieck, PJ Kostenuik, ...
Journal of Applied Physiology 106 (2), 582-595, 2009
2572009
Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis
JR Canon, M Roudier, R Bryant, S Morony, M Stolina, PJ Kostenuik, ...
Clinical & experimental metastasis 25, 119-129, 2008
2442008
RANKL inhibition through osteoprotegerin blocks bone loss in experimental periodontitis
Q Jin, JA Cirelli, CH Park, JV Sugai, M Taba Jr, PJ Kostenuik, ...
Journal of periodontology 78 (7), 1300-1308, 2007
2442007
Estrogen regulates bone turnover by targeting RANKL expression in bone lining cells
C Streicher, A Heyny, O Andrukhova, B Haigl, S Slavic, C Schüler, ...
Scientific reports 7 (1), 1-14, 2017
2102017
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