Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine NT Awatade, SL Wong, CK Hewson, LK Fawcett, A Kicic, A Jaffe, ... Frontiers in Pharmacology 9, 1429, 2018 | 82 | 2018 |
Significant functional differences in differentiated Conditionally Reprogrammed (CRC)-and Feeder-free Dual SMAD inhibited-expanded human nasal epithelial cells NT Awatade, SL Wong, A Capraro, E Pandzic, I Slapetova, L Zhong, ... Journal of Cystic Fibrosis 20 (2), 364-371, 2021 | 31 | 2021 |
Henoch-Schönlein purpura with posterior reversible encephalopathy syndrome M Dasarathi, D Birchall, C De San Lazaro, LK Fawcett, JA Eyre Pediatric Neurology 46 (1), 42-43, 2012 | 21 | 2012 |
Molecular dynamics and theratyping in airway and gut organoids reveal R352Q-CFTR conductance defect SL Wong, NT Awatade, MA Astore, KM Allan, MJ Carnell, I Slapetova, ... American Journal of Respiratory Cell and Molecular Biology 67 (1), 99-111, 2022 | 13 | 2022 |
Collection, expansion, and differentiation of primary human nasal epithelial cell models for quantification of cilia beat frequency KM Allan, SL Wong, LK Fawcett, A Capraro, A Jaffe, C Herbert, E Pandzic, ... JoVE (Journal of Visualized Experiments), e63090, 2021 | 10 | 2021 |
Avatar acceptability: views from the Australian Cystic Fibrosis community on the use of personalised organoid technology to guide treatment decisions LK Fawcett, CE Wakefield, S Sivam, PG Middleton, P Wark, J Widger, ... ERJ open research 7 (1), 2021 | 8 | 2021 |
Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity SL Wong, NT Awatade, MA Astore, KM Allan, MJ Carnell, I Slapetova, ... Iscience 25 (1), 2022 | 7 | 2022 |
Comparing Cytology Brushes for Optimal Human Nasal Epithelial Cell Collection: Implications for Airway Disease Diagnosis and Research LK Fawcett, N Turgutoglu, KM Allan, Y Belessis, J Widger, A Jaffe, ... Journal of Personalized Medicine 13 (5), 864, 2023 | 3 | 2023 |
S945L-CFTR molecular dynamics, functional characterization and tezacaftor/ivacaftor efficacy in vivo and in vitro in matched pediatric patient-derived cell models KM Allan, MA Astore, LK Fawcett, SL Wong, PC Chen, R Griffith, A Jaffe, ... Frontiers in Pediatrics 10, 1062766, 2022 | 3 | 2022 |
Case report: Cholecystoduodenostomy for cholestatic liver disease in a premature infant with cystic fibrosis and short gut syndrome LK Fawcett, J Widger, GM Henry, CY Ooi BMC Pediatrics 19 (78), 2019 | 3 | 2019 |
Q1291H-CFTR molecular dynamics simulations and ex vivo theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient KM Allan, MA Astore, E Kardia, SL Wong, LK Fawcett, JL Bell, S Visser, ... Frontiers in Molecular Biosciences 10, 1148501, 2023 | 1 | 2023 |
Significant functional differences despite morphological and molecular similarity in fully differentiated matched Conditionally Reprogrammed (CRC) and Feeder free dual SMAD … NT Awatade, SL Wong, E Pandzic, I Slapetova, A Capraro, L Zhong, ... bioRxiv, 2020.05. 29.120006, 2020 | 1 | 2020 |
Providing Australian children and adolescents with equitable access to new and emerging therapies through clinical trials: a call to action MS Lorentzos, D Metz, AS Moore, LK Fawcett, P Bray, L Attwood, ... The Medical Journal of Australia 220 (3), n/a-n/a, 2024 | | 2024 |
WS14. 02 Cystic fibrosis personalised medicine; paediatric in vitro airway cell models to predict CFTR modulator patient outcomes LK Fawcett, A Jaffe, SA Waters Journal of Cystic Fibrosis 22, S28, 2023 | | 2023 |
Paediatric in vitro airway cell models to predict CFTR modulator patient outcomes L Fawcett, A Jaffe, S Waters RESPIROLOGY 28, 44-44, 2023 | | 2023 |
Real world impact of 13vPCV in preventing invasive pneumococcal pneumonia in Australian children: A national study N Homaira, R Strachan, H Quinn, S Beggs, M Bhuiyan, A Bowen, ... Vaccine 41 (1), 85-91, 2023 | | 2023 |
In silico and functional characterisation of an ultra-rare CFTR mutation identifies novel lasso motif interactions regulating channel gating SL Wong, NT Awatade, MA Astore, KM Allan, MJ Carnell, I Slapetova, ... bioRxiv, 2021.12. 12.472297, 2021 | | 2021 |
UTILIZING MULTIPLE BREATH WASHOUT TO MONITOR CHANGES IN AIRWAY FUNCTION IN CHILDREN WITH CYSTIC FIBROSIS AFTER COMMENCING ORKAMBId (R) OR SYMDEKO L Plush, J McBride, Y Belesses, L Fawcett, Y Mechin, A Jaffe RESPIROLOGY 26, 4-4, 2021 | | 2021 |
TP078 ACCEPTABILITY OF USING PERSONALISED MINI‐ORGAN‐AVATARS TO ACCELERATE DRUG DISCOVERY AND PREDICT DRUG RESPONSE IN CYSTIC FIBROSIS PATIENTS WS FAWCETT L, WAKEFIELD C, WIDGER J, JAFFE A Respirology 25 ((Suppl 1)), 114-230, 2020 | | 2020 |
INTESTINAL CURRENT MEASUREMENT AS DIAGNOSTIC AND SURROGATE MARKER OF CFTR FUNCTION IN CF N Awatade, S Wong, N Turgutoglu, L Fawcett, K Ooi, J Widger, A Jaffe, ... RESPIROLOGY 25, 55-55, 2020 | | 2020 |