Lin-Feng Chen
Lin-Feng Chen
University of Illinopis at Urbana-Champaign
Verified email at - Homepage
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Shaping the nuclear action of NF-κB
LF Chen, WC Greene
Nature reviews Molecular cell biology 5 (5), 392-401, 2004
Duration of nuclear NF-κB action regulated by reversible acetylation
L Chen, W Fischle, E Verdin, WC Greene
Science 293 (5535), 1653-1657, 2001
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF‐κB
L Chen, Y Mu, WC Greene
The EMBO journal, 2002
SIRT1 protects against microglia-dependent amyloid-β toxicity through inhibiting NF-κB signaling
J Chen, Y Zhou, S Mueller-Steiner, LF Chen, H Kwon, S Yi, L Mucke, ...
Journal of Biological Chemistry 280 (48), 40364-40374, 2005
Brd4 coactivates transcriptional activation of NF-κB via specific binding to acetylated RelA
B Huang, XD Yang, MM Zhou, K Ozato, LF Chen
Molecular and cellular biology, 2009
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
R Yagi, LF Chen, K Shigesada, Y Murakami, Y Ito
The EMBO journal 18 (9), 2551-2562, 1999
Interaction and functional cooperation of PEBP2/CBF with Smads: synergistic induction of the immunoglobulin germline Cα promoter
J Hanai, LF Chen, T Kanno, N Ohtani-Fujita, WY Kim, WH Guo, T Imamura, ...
Journal of Biological Chemistry 274 (44), 31577-31582, 1999
NF‐κB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
SA Williams, LF Chen, H Kwon, CM Ruiz‐Jarabo, E Verdin, WC Greene
The EMBO journal 25 (1), 139-149, 2006
NF-κB RelA phosphorylation regulates RelA acetylation
LF Chen, SA Williams, Y Mu, H Nakano, JM Duerr, L Buckbinder, ...
Molecular and cellular biology 25 (18), 7966-7975, 2005
Prostratin antagonizes HIV latency by activating NF-κB
SA Williams, LF Chen, H Kwon, D Fenard, D Bisgrove, E Verdin, ...
Journal of Biological Chemistry 279 (40), 42008-42017, 2004
Posttranslational modifications of NF-κB: another layer of regulation for NF-κB signaling pathway
B Huang, XD Yang, A Lamb, LF Chen
Cellular signalling 22 (9), 1282-1290, 2010
Regulation of distinct biological activities of the NF-κB transcription factor complex by acetylation
LF Chen, WC Greene
Journal of molecular medicine 81, 549-557, 2003
p53 induces NF-κB activation by an IκB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1
J Bohuslav, L Chen, H Kwon, Y Mu, WC Greene
Journal of Biological Chemistry 279 (25), 26115-26125, 2004
Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA
Z Zou, B Huang, X Wu, H Zhang, J Qi, J Bradner, S Nair, LF Chen
Oncogene 33 (18), 2395-2404, 2014
Role of the Helicobacter pylori‐Induced inflammatory response in the development of gastric cancer
A Lamb, LF Chen
Journal of cellular biochemistry 114 (3), 491-497, 2013
Negative regulation of NF‐κB action by Set9‐mediated lysine methylation of the RelA subunit
XD Yang, B Huang, M Li, A Lamb, NL Kelleher, LF Chen
The EMBO journal 28 (8), 1055-1066, 2009
Intrinsic transcriptional activation-inhibition domains of the polyomavirus enhancer binding protein 2/core binding factor α subunit revealed in the presence of the β subunit
T Kanno, Y Kanno, LF Chen, E Ogawa, WY Kim, Y Ito
Molecular and cellular biology 18 (5), 2444-2454, 1998
NF-κB is essential for induction of CYLD, the negative regulator of NF-κB: evidence for a novel inducible autoregulatory feedback pathway
H Jono, JH Lim, LF Chen, H Xu, E Trompouki, ZK Pan, G Mosialos, JD Li
Journal of Biological Chemistry 279 (35), 36171-36174, 2004
Helicobacter pylori CagA activates NF‐κB by targeting TAK1 for TRAF6‐mediated Lys 63 ubiquitination
A Lamb, XD Yang, YHN Tsang, JD Li, H Higashi, M Hatakeyama, ...
EMBO reports 10 (11), 1242-1249, 2009
Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation
HS Kwon, MM Brent, R Getachew, P Jayakumar, LF Chen, M Schnolzer, ...
Cell host & microbe 3 (3), 158-167, 2008
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