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Lester S. Manly
Lester S. Manly
Graduate Student, Molecular & Systems Pharmacology, Emory University
Verified email at emory.edu - Homepage
Title
Cited by
Cited by
Year
Late-onset Alzheimer disease risk variants mark brain regulatory loci
M Allen, M Kachadoorian, MM Carrasquillo, A Karhade, L Manly, ...
Neurology: Genetics 1 (2), e15, 2015
742015
[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain
X Yan, S Telu, RM Dick, JS Liow, P Zanotti-Fregonara, CL Morse, ...
Journal of Cerebral Blood Flow & Metabolism 41 (10), 2571-2582, 2021
182021
PET quantification of brain O-GlcNAcase with [18F]LSN3316612 in healthy human volunteers
JH Lee, JS Liow, S Paul, CL Morse, MB Haskali, L Manly, S Shcherbinin, ...
EJNMMI research 10, 1-12, 2020
182020
Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising 18F-Labeled Ligand
FG Siméon, JH Lee, CL Morse, I Stukes, SS Zoghbi, LS Manly, JS Liow, ...
Journal of medicinal chemistry 64 (22), 16731-16745, 2021
172021
Synthesis of [18F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey
C Taddei, CL Morse, MJ Kim, JS Liow, J Montero Santamaria, A Zhang, ...
ACS chemical neuroscience 12 (3), 517-530, 2021
152021
Discovery, radiolabeling, and evaluation of subtype-selective inhibitors for positron emission tomography imaging of brain phosphodiesterase-4D
Y Wakabayashi, S Telu, RM Dick, M Fujita, M Ooms, CL Morse, JS Liow, ...
ACS chemical neuroscience 11 (9), 1311-1323, 2020
122020
Cyclooxygenases as potential PET imaging biomarkers to explore neuroinflammation in dementia
BV Kenou, LS Manly, SB Rubovits, SA Umeozulu, MG Van Buskirk, ...
Journal of Nuclear Medicine 63 (Supplement 1), 53S-59S, 2022
82022
Late-onset Alzheimer disease risk variants mark brain regulatory loci. Neurol Genet. 2015; 1 (2): e15
M Allen, M Kachadoorian, MM Carrasquillo, A Karhade, L Manly, ...
4
11C-MC1 has adequate sensitivity to measure low density cyclooxygenase 2 (COX-2) in healthy human brain
X Yan, A Zhang, S Zoghbi, JS Liow, C Morse, MF Araneta, L Manly, ...
Journal of Nuclear Medicine 62 (supplement 1), 103-103, 2021
32021
In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain
X Yan, FG Siméon, JS Liow, CL Morse, JA Montero Santamaria, ...
European Journal of Nuclear Medicine and Molecular Imaging 50 (10), 2962-2970, 2023
12023
Whole-Body PET Imaging in Humans Shows That 11C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs
MJ Kim, FJ Anaya, LS Manly, JH Lee, J Hong, S Shrestha, S Telu, ...
Journal of Nuclear Medicine 64 (1), 159-164, 2023
12023
Aspirin blockade of COX-1 in human organs is reduced by plasma as shown by PET imaging and blood assays with 11C-PS13
L Manly, MJ Kim, JM Santamaria, A Zhang, FJ Anaya, J Hong, W Miller, ...
Journal of Nuclear Medicine 62 (supplement 1), 115-115, 2021
12021
PET measurement of cyclooxygenase-2 (COX-2) with 11C-MC1 in healthy human brain
X Yan, A Zhang, C Morse, JS Liow, MJ Kim, JAM Santamaria, ...
Journal of Nuclear Medicine 64 (supplement 1), P87-P87, 2023
2023
175. A Novel 18F-Labeled Pet Radioligand Accurately Quantifies Translocator Protein 18kDa (TSPO) in Monkey Brain
M Jenkins, X Yan, F Siméon, JS Liow, C Morse, JM Santamaria, L Manly, ...
Biological Psychiatry 93 (9), S165, 2023
2023
Candidate 3-benzazepine-1-ol type GluN2B receptor radioligands (11C-NR2B-Me enantiomers) have high binding in cerebellum but not to σ1 receptors
L Cai, JS Liow, CL Morse, S Telu, R Davies, LS Manly, SS Zoghbi, ...
EJNMMI research 13 (1), 28, 2023
2023
In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in monkey brain
X Yan, FG Siméon, JS Liow, CL Morse, JAM Santamaria, M Jenkins, ...
2022
11C-MC1 has adequate sensitivity to measure low density cyclooxygenase 2 (COX-2) in healthy human brain
X Yan, A Zhang, C Morse, JS Liow, MJ Kim, MDF Araneta, ...
Journal of Nuclear Medicine 63 (supplement 2), 2317-2317, 2022
2022
[C-11] MC1 has adequate sensitivity to measure low density cyclooxygenase 2 (COX-2) in healthy human brain
X Yan, A Zhang, SS Zoghbi, JS Liow, C Morse, MJ Kim, MF Araneta, ...
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 41 (1_ SUPPL), 140-140, 2021
2021
Quantification and kinetic analysis of [C-11] deschloroclozapine positron emission tomography imaging for designer receptors exclusively activated by designer drugs in monkey brain
X Yan, R Dick, S Telu, M Eldridge, JS Liow, P Zanotti-Fregonara, C Morse, ...
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 41 (1_ SUPPL), 218-219, 2021
2021
NR2B
L Cai, JS Liow, C Morse, R Davies, L Manly, S Zoghbi, R Innis, V Pike
Journal of Nuclear Medicine 61 (supplement 1), 83-83, 2020
2020
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