| Estrogen activation of G-protein–coupled estrogen receptor 1 regulates phosphoinositide 3-kinase and mTOR signaling to promote liver growth in zebrafish and proliferation of … S Chaturantabut, A Shwartz, KJ Evason, AG Cox, K Labella, AG Schepers, ... Gastroenterology 156 (6), 1788-1804. e13, 2019 | 88 | 2019 |
| Epidemiological, clinical and biochemical characterization of the p.(Ala359Asp) SMPD1 variant causing Niemann–Pick disease type B M Acuña, P Martínez, C Moraga, X He, M Moraga, B Hunter, P Nuernberg, ... European Journal of Human Genetics 24 (2), 208-213, 2016 | 39 | 2016 |
| Thioesterase superfamily member 2 promotes hepatic VLDL secretion by channeling fatty acids into triglyceride biosynthesis M Alves‐Bezerra, Y Li, M Acuña, AA Ivanova, KE Corey, EA Ortlund, ... Hepatology 70 (2), 496-510, 2019 | 27 | 2019 |
| Mutational Screening of the APC Gene in Chilean Families with Familial Adenomatous Polyposis: Nine Novel Truncating Mutations MK De la Fuente, KP Alvarez, AJ Letelier, F Bellolio, ML Acuña, FS León, ... Diseases of the Colon & Rectum 50, 2142-2148, 2007 | 20 | 2007 |
| Deficiency of Niemann‐Pick C1 protein protects against diet‐induced gallstone formation in mice MG Morales, L Amigo, E Balboa, M Acuña, J Castro, H Molina, JF Miquel, ... Liver International 30 (6), 887-897, 2010 | 15 | 2010 |
| Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP A Mendoza, C Tang, J Choi, M Acuña, M Logan, AG Martin, ... Science signaling 14 (709), eabh3839, 2021 | 13 | 2021 |
| c-Abl activation linked to autophagy-lysosomal dysfunction contributes to neurological impairment in Niemann-Pick type A disease T Marín, AE Dulcey, F Campos, C de la Fuente, M Acuña, J Castro, ... Frontiers in Cell and Developmental Biology 10, 844297, 2022 | 12 | 2022 |
| ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016 T Velasquez, G Mackey, J Lusk, UG Kyle, T Fontenot, P Marshall, ... Intensive Care Medicine Experimental 4, 405-607, 2016 | 9 | 2016 |
| Structural and functional analysis of the ASM p. Ala359Asp mutant that causes acid sphingomyelinase deficiency M Acuña, V Castro-Fernández, M Latorre, J Castro, EH Schuchman, ... Biochemical and biophysical research communications 479 (3), 496-501, 2016 | 8 | 2016 |
| Transgenic overexpression of Niemann-Pick C2 protein promotes cholesterol gallstone formation in mice M Acuña, L González-Hódar, L Amigo, J Castro, MG Morales, GI Cancino, ... Journal of hepatology 64 (2), 361-369, 2016 | 6 | 2016 |
| Acyl-CoA thioesterase 12 suppresses YAP-mediated hepatocarcinogenesis by limiting glycerolipid biosynthesis H He, A Sugiyama, NW Snyder, MG Teneche, X Liu, KM Maner-Smith, ... Cancer Letters 565, 216210, 2023 | 3 | 2023 |
| Lipoprotein Metabolism and Cholesterol Balance M Acuña‐Aravena, DE Cohen The Liver: Biology and Pathobiology, 255-267, 2020 | 3 | 2020 |
| Effect of a pescetarian and vegan diet on fatty acid composition in blood and spermatozoa in young healthy men R Chamorro, R Farías, P Allende, M Acuña, P Cáceres, F Gómez, A Ortiz, ... Prostaglandins, Leukotrienes and Essential Fatty Acids 196, 102582, 2023 | 1 | 2023 |
| Multimodal control of nutrient biosynthesis in liver by acyl-CoA thioesterase 12 (Acot12) M Acuna, H He, Y Li, H Li, DE Cohen The Liver Meeting Digital Experience™, 2020 | 1 | 2020 |
| High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease CS Krumm, RS Landzberg, L Ramos-Espiritu, C Adura, X Liu, M Acuna, ... Molecular Metabolism 78, 101832, 2023 | | 2023 |
| NUCLEAR LOCALIZATION OF ACYL-CoA THIOESTERASE 12 PROTECTS AGAINST HEPATIC STEATOSIS BY REDUCING PPARG ACETYLATION M Acuna, X Xu, H He, LH Ang, A Sugiyama, SJ Hagen, DE Cohen HEPATOLOGY 78, S2002-S2003, 2023 | | 2023 |
| ACYL-CoA THIOESTERASE 12 ACTIVATES THE HIPPO PATHWAY BY LIMITING LYSOPHOSPHATIDIC ACID BIOSYNTHESIS: IMPLICATIONS FOR HEPATOCARCINOGENESIS H He, M Acuna, H Najafi-Shoushtari, DE Cohen HEPATOLOGY 76, S1412-S1412, 2022 | | 2022 |
| ACYL-CoA THIOESTERASE 12 LIMITS HEPATIC GLUCONEOGENESIS BY REDUCING TCA CYCLE FLUXES: IMPLICATIONS FOR NAFLD PATHOGENESIS M Acuna, WM Oldham, NW Snyder, I Soaita, N Yucel, Z Arany, DE Cohen HEPATOLOGY 76, S1266-S1267, 2022 | | 2022 |
| A SMALL MOLECULE INHIBITOR TARGETING THIOESTERASE SUPERFAMILY MEMBER 1 INCREASES HEPATOCELLULAR FATTY ACID OXIDATION AND REDUCES GLUCOSE PRODUCTION: IMPLICATIONS FOR NAFLD … C Krumm, M Acuna, Y Xie, A Sugiyama, DE Cohen HEPATOLOGY 76, S767-S767, 2022 | | 2022 |
| MICROBIOME-DERIVED METABOLITES IN PORTAL BLOOD OF MICE SUPPRESS HEPATIC GLUCONEOGENESIS: IMPLICATIONS FOR THE MANAGEMENT OF NAFLD ML Yeh, M Acuna, WL Chuang, ML Yu, DE Cohen, TI Krisko HEPATOLOGY 74, 363A-363A, 2021 | | 2021 |
