| Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial K Abe, M Aoki, S Tsuji, Y Itoyama, G Sobue, M Togo, C Hamada, ... The Lancet Neurology 16 (7), 505-512, 2017 | 626 | 2017 |
| α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A β-amyloid-induced neurotoxicity T Kihara, S Shimohama, H Sawada, K Honda, T Nakamizo, H Shibasaki, ... Journal of Biological Chemistry 276 (17), 13541-13546, 2001 | 502 | 2001 |
| Nicotinic receptor stimulation protects neurons against β‐amyloid toxicity T Kihara, S Shimohama, H Sawada, J Kimura, T Kume, H Kochiyama, ... Annals of Neurology: Official Journal of the American Neurological …, 1997 | 418 | 1997 |
| Estradiol protects mesencephalic dopaminergic neurons from oxidative stress‐induced neuronal death H Sawada, M Ibi, T Kihara, M Urushitani, A Akaike, S Shimohama Journal of neuroscience research 54 (5), 707-719, 1998 | 322 | 1998 |
| Donepezil for dementia with Lewy bodies: A randomized, placebo‐controlled trial E Mori, M Ikeda, K Kosaka, Donepezil‐DLB Study Investigators Annals of neurology 72 (1), 41-52, 2012 | 310 | 2012 |
| Phosphatidylinositol 3‐kinase mediates neuroprotection by estrogen in cultured cortical neurons K Honda, H Sawada, T Kihara, M Urushitani, T Nakamizo, A Akaike, ... Journal of neuroscience research 60 (3), 321-327, 2000 | 300 | 2000 |
| Protective effects of 1α, 25-(OH) 2D3 against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture M Ibi, H Sawada, M Nakanishi, T Kume, H Katsuki, S Kaneko, ... Neuropharmacology 40 (6), 761-771, 2001 | 292 | 2001 |
| Stimulation of α4β2 nicotinic acetylcholine receptors inhibits β-amyloid toxicity T Kihara, S Shimohama, M Urushitani, H Sawada, J Kimura, T Kume, ... Brain research 792 (2), 331-334, 1998 | 246 | 1998 |
| Disease model: Parkinson's disease S Shimohama, H Sawada, Y Kitamura, T Taniguchi Trends in molecular medicine 9 (8), 360-365, 2003 | 244 | 2003 |
| Altered plasticity of the human motor cortex in Parkinson's disease Y Ueki, T Mima, M Ali Kotb, H Sawada, H Saiki, A Ikeda, T Begum, F Reza, ... Annals of neurology 59 (1), 60-71, 2006 | 225 | 2006 |
| Safety and efficacy of rituximab in neuromyelitis optica spectrum disorders (RIN-1 study): a multicentre, randomised, double-blind, placebo-controlled trial M Tahara, T Oeda, K Okada, T Kiriyama, K Ochi, H Maruyama, H Fukaura, ... The Lancet Neurology 19 (4), 298-306, 2020 | 223 | 2020 |
| Mechanisms of antiapoptotic effects of estrogens in nigral dopaminergic neurons H Sawada, M Ibi, T Kihara, M Urushitani, K Honda, M Nakanishi, A Akaike, ... The FASEB Journal 14 (9), 1202-1214, 2000 | 211 | 2000 |
| N‐methyl‐D‐aspartate receptor‐mediated mitochondrial Ca2+ overload in acute excitotoxic motor neuron death: A mechanism distinct from chronic neurotoxicity after Ca … M Urushitani, Tomoki, Nakamizo, R Inoue, H Sawada, T Kihara, K Honda, ... Journal of neuroscience research 63 (5), 377-387, 2001 | 173 | 2001 |
| Amantadine for dyskinesias in Parkinson's disease: a randomized controlled trial H Sawada, T Oeda, S Kuno, M Nomoto, K Yamamoto, M Yamamoto, ... PloS one 5 (12), e15298, 2010 | 170 | 2010 |
| Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease N Yamamoto, H Sawada, Y Izumi, T Kume, H Katsuki, S Shimohama, ... Journal of Biological Chemistry 282 (7), 4364-4372, 2007 | 165 | 2007 |
| Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons K Honda, S Shimohama, H Sawada, T Kihara, T Nakamizo, H Shibasaki, ... Journal of neuroscience research 64 (5), 466-475, 2001 | 164 | 2001 |
| Clinical efficacy of edaravone for the treatment of amyotrophic lateral sclerosis H Sawada Expert opinion on pharmacotherapy 18 (7), 735-738, 2017 | 162 | 2017 |
| Galantamine modulates nicotinic receptor and blocks Aβ-enhanced glutamate toxicity T Kihara, H Sawada, T Nakamizo, R Kanki, H Yamashita, A Maelicke, ... Biochemical and biophysical research communications 325 (3), 976-982, 2004 | 150 | 2004 |
| Dopamine D2‐type agonists protect mesencephalic neurons from glutamate neurotoxicity: Mechanisms of neuroprotective treatment against oxidative stress H Sawada, M Ibi, T Kihara, M Urushitani, A Akaike, J Kimura, ... Annals of Neurology: Official Journal of the American Neurological …, 1998 | 145 | 1998 |
| Endogenously Occurring β‐Carboline Induces Parkinsonism in Nonprimate Animals: A Possible Causative Protoxin in Idiopathic Parkinson's Disease K Matsubara, T Gonda, H Sawada, T Uezono, Y Kobayashi, T Kawamura, ... Journal of neurochemistry 70 (2), 727-735, 1998 | 145 | 1998 |
Akinori AkaikeWakayama Medical University, Kyoto UniversityVerified email at ps.nagoya-u.ac.jp
