| Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory … H Chu, JFW Chan, TTT Yuen, H Shuai, S Yuan, Y Wang, B Hu, CCY Yip, ... The Lancet Microbe 1 (1), e14-e23, 2020 | 851 | 2020 |
| Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, Y Hou, H Shuai, D Yang, ... Clinical Infectious Diseases 71 (6), 1400-1409, 2020 | 732 | 2020 |
| Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways H Chu, J Zhou, BHY Wong, C Li, JFW Chan, ZS Cheng, D Yang, D Wang, ... The Journal of infectious diseases 213 (6), 904-914, 2016 | 479 | 2016 |
| Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus J Zhou, C Li, G Zhao, H Chu, D Wang, HHN Yan, VKM Poon, L Wen, ... Science advances 3 (11), eaao4966, 2017 | 431 | 2017 |
| Characterization of the lipidomic profile of human coronavirus-infected cells: implications for lipid metabolism remodeling upon coronavirus replication B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan, H Shuai, Y Wang, ... Viruses 11 (1), 73, 2019 | 259 | 2019 |
| SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 232 | 2019 |
| Attenuated interferon and proinflammatory response in SARS-CoV-2–infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation D Yang, H Chu, Y Hou, Y Chai, H Shuai, ACY Lee, X Zhang, Y Wang, ... The Journal of infectious diseases 222 (5), 734-745, 2020 | 193 | 2020 |
| Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza Z Cheng, J Zhou, KKW To, H Chu, C Li, D Wang, D Yang, S Zheng, K Hao, ... The Journal of infectious diseases 212 (8), 1214-1221, 2015 | 181 | 2015 |
| Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells H Chu, CM Chan, X Zhang, Y Wang, S Yuan, J Zhou, RKH Au-Yeung, ... Journal of Biological Chemistry 293 (30), 11709-11726, 2018 | 178 | 2018 |
| Virus capture and destruction by label‐free graphene oxide for detection and disinfection applications Z Song, X Wang, G Zhu, Q Nian, H Zhou, D Yang, C Qin, R Tang Small 11 (9-10), 1171-1176, 2015 | 147 | 2015 |
| Host and viral determinants for efficient SARS-CoV-2 infection of the human lung H Chu, B Hu, X Huang, Y Chai, D Zhou, Y Wang, H Shuai, D Yang, Y Hou, ... Nature communications 12 (1), 134, 2021 | 129 | 2021 |
| Emerging SARS-CoV-2 variants expand species tropism to murines H Shuai, JFW Chan, TTT Yuen, C Yoon, JC Hu, L Wen, B Hu, D Yang, ... EBioMedicine 73, 2021 | 123 | 2021 |
| Carcinoembryonic antigen-related cell adhesion molecule 5 is an important surface attachment factor that facilitates entry of Middle East respiratory syndrome coronavirus CM Chan, H Chu, Y Wang, BHY Wong, X Zhao, J Zhou, D Yang, ... Journal of virology 90 (20), 9114-9127, 2016 | 86 | 2016 |
| Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity H Chu, H Shuai, Y Hou, X Zhang, L Wen, X Huang, B Hu, D Yang, ... Science advances 7 (25), eabf8577, 2021 | 60 | 2021 |
| Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation X Zhang, H Chu, L Wen, H Shuai, D Yang, Y Wang, Y Hou, Z Zhu, S Yuan, ... Emerging microbes & infections 9 (1), 733-746, 2020 | 60 | 2020 |
| Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection ZW Ye, S Yuan, JFW Chan, AJ Zhang, CY Yu, CP Ong, D Yang, ... Emerging microbes & infections 10 (1), 291-304, 2021 | 57 | 2021 |
| Vaccine engineering with dual‐functional mineral shell: a promising strategy to overcome preexisting immunity X Wang, C Sun, P Li, T Wu, H Zhou, D Yang, Y Liu, X Ma, Z Song, Q Nian, ... Advanced Materials 28 (4), 694-700, 2016 | 52 | 2016 |
| Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-β and IFN inducer H Shuai, H Chu, Y Hou, D Yang, Y Wang, B Hu, X Huang, X Zhang, ... Journal of Infection 81 (4), e1-e10, 2020 | 49 | 2020 |
| Activation of C-type lectin receptor and (RIG)-I-like receptors contributes to proinflammatory response in middle east respiratory syndrome coronavirus-infected macrophages X Zhao, H Chu, BHY Wong, MC Chiu, D Wang, C Li, X Liu, D Yang, ... The Journal of infectious diseases 221 (4), 647-659, 2020 | 49 | 2020 |
| SARS-CoV-2 induces a more robust innate immune response and replicates less efficiently than SARS-CoV in the human intestines: an ex vivo study with implications on … H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, H Shuai, D Yang, B Hu, ... Cellular and molecular gastroenterology and hepatology 11 (3), 771-781, 2021 | 47 | 2021 |
