Efficient targeted integration directed by short homology in zebrafish and mammalian cells WA Wierson, JM Welker, MP Almeida, CM Mann, DA Webster, ME Torrie, ... Elife 9, e53968, 2020 | 107 | 2020 |
Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation LE Schultz, JA Haltom, MP Almeida, WA Wierson, SL Solin, TJ Weiss, ... Disease models & mechanisms 11 (6), dmm034124, 2018 | 50 | 2018 |
Expanding the CRISPR toolbox with ErCas12a in zebrafish and human cells WA Wierson, BW Simone, Z WareJoncas, C Mann, JM Welker, B Kar, ... The CRISPR journal 2 (6), 417-433, 2019 | 47 | 2019 |
GeneWeld: efficient targeted integration directed by short homology in zebrafish JM Welker, WA Wierson, MP Almeida, CM Mann, ME Torrie, Z Ming, ... Bio-protocol 11 (14), e4100-e4100, 2021 | 24 | 2021 |
CAR T cell immunotherapy in human and veterinary oncology: changing the odds against hematological malignancies JP Mochel, SC Ekker, CM Johannes, AE Jergens, K Allenspach, ... The AAPS Journal 21, 1-12, 2019 | 24 | 2019 |
The Gene Sculpt Suite: a set of tools for genome editing CM Mann, G Martínez-Gálvez, JM Welker, WA Wierson, H Ata, ... Nucleic acids research 47 (W1), W175-W182, 2019 | 16 | 2019 |
Cre/lox regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration F Liu, S Kambakam, MP Almeida, Z Ming, JM Welker, WA Wierson, ... Elife 11, e71478, 2022 | 13 | 2022 |
GeneWeld: a method for efficient targeted integration directed by short homology WA Wierson, JM Welker, MP Almeida, CM Mann, DA Webster, TJ Weiss, ... BioRxiv, 431627, 2018 | 11 | 2018 |
Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis LE Schultz‐Rogers, ML Thayer, S Kambakam, WA Wierson, JA Helmer, ... Developmental Dynamics 251 (8), 1267-1290, 2022 | 9 | 2022 |
GoldyTALEN vectors with improved efficiency for golden gate TALEN assembly JM Welker, WA Wierson, Y Wang, TL Poshusta, MS McNulty, EE Tisdale, ... Human gene therapy 27 (6), 423, 2016 | 6 | 2016 |
Vascular endothelial growth factor a and leptin expression associated with ectopic proliferation and retinal dysplasia in zebrafish optic pathway tumors LE Schultz, SL Solin, WA Wierson, JM Lovan, J Syrkin-Nikolau, ... Zebrafish 14 (4), 343-356, 2017 | 5 | 2017 |
Effect of ARTEMIS (DCLRE1C) deficiency and microinjection timing on editing efficiency during somatic cell nuclear transfer and in vitro fertilization using the CRISPR/Cas9 system Y Li, MK Adur, W Wang, RB Schultz, B Hale, W Wierson, SE Charley, ... Theriogenology 170, 107-116, 2021 | 2 | 2021 |
Retinoblastoma binding protein 4 maintains cycling neural stem cells and prevents DNA damage and Tp53-dependent apoptosis in rb1 mutant neural progenitors LE Schultz-Rogers, MP Almeida, WA Wierson, M Kool, M McGrail BioRxiv, 427344, 2018 | 2 | 2018 |
Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression O Sirpilla, RL Sakemura, M Hefazi, TN Huynh, I Can, JH Girsch, ... Nature Biomedical Engineering, 1-18, 2024 | 1 | 2024 |
Gene editing and gene therapy in oncology WA Wierson, AM Abel, EL Siegler, SC Ekker, CM Johannes, ... Therapeutic Strategies in Veterinary Oncology, 155-180, 2023 | 1 | 2023 |
Zebrafish Cre/lox regulated UFlip alleles generated by CRISPR/Cas targeted integration provide cell-type specific conditional gene inactivation MP Almeida, S Kambakam, F Liu, Z Ming, JM Welker, WA Wierson, ... bioRxiv, 2021.06. 18.448732, 2021 | 1 | 2021 |
Su1046–Crispr/Cas9-Mediated Genome Editing of Multi-Drug Resistance Proteins in a Novel Canine Enteroid Model DC Borcherding, YM Ambrosini, T Atherly, T Rudolph, J Essner, ... Gastroenterology 156 (6), S-494, 2019 | 1 | 2019 |
Expanding the CRISPR toolbox with mad7 in zebrafish and human cells WA Wierson, BW Simone, Z WareJoncas, C Mann, JM Welker, ... bioRxiv, 650515, 2019 | 1 | 2019 |
Role of the tumour microenvironment in bladder cancer pathogenesis and value of the reverse translational approach: a tale of two species BH Ahmed, C Zdyrski, J Cheville, N Rancilio, AM Abel, WA Wierson, ... Clinical and Translational Discovery 3 (5), e235, 2023 | | 2023 |
Use of Short Homology for Targeted Integration in Zebrafish. WA Wierson, JM Welker, MP Almeida, CM Mann, DA Webster, ME Torrie, ... IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 57 (SUPPL 1), S2-S2, 2021 | | 2021 |