| Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling M Acar, H Jafar-Nejad, H Takeuchi, A Rajan, D Ibrani, NA Rana, H Pan, ... Cell 132 (2), 247-258, 2008 | 360 | 2008 |
| Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains HO Ishikawa, H Takeuchi, RS Haltiwanger, KD Irvine Science 321 (5887), 401-404, 2008 | 283 | 2008 |
| Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi R Fernandez-Valdivia, H Takeuchi, A Samarghandi, M Lopez, J Leonardi, ... Development 138 (10), 1925-1934, 2011 | 190 | 2011 |
| Significance of glycosylation in Notch signaling H Takeuchi, RS Haltiwanger Biochemical and biophysical research communications 453 (2), 235-242, 2014 | 183 | 2014 |
| The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high … HH Wandall, F Irazoqui, MA Tarp, EP Bennett, U Mandel, H Takeuchi, ... Glycobiology 17 (4), 374-387, 2007 | 139 | 2007 |
| Identification of glycosyltransferase 8 family members as xylosyltransferases acting on O-glucosylated notch epidermal growth factor repeats MK Sethi, FFR Buettner, VB Krylov, H Takeuchi, NE Nifantiev, ... Journal of biological chemistry 285 (3), 1582-1586, 2010 | 132 | 2010 |
| Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands P Taylor, H Takeuchi, D Sheppard, C Chillakuri, SM Lea, RS Haltiwanger, ... Proceedings of the National Academy of Sciences 111 (20), 7290-7295, 2014 | 119 | 2014 |
| In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe A Xu, N Haines, M Dlugosz, NA Rana, H Takeuchi, RS Haltiwanger, ... Journal of biological chemistry 282 (48), 35153-35162, 2007 | 118 | 2007 |
| Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism H Yu, M Takeuchi, J LeBarron, J Kantharia, E London, H Bakker, ... Nature chemical biology 11 (11), 847-854, 2015 | 108 | 2015 |
| O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1 NA Rana, A Nita-Lazar, H Takeuchi, S Kakuda, KB Luther, ... Journal of Biological Chemistry 286 (36), 31623-31637, 2011 | 108 | 2011 |
| O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking H Takeuchi, H Yu, H Hao, M Takeuchi, A Ito, H Li, RS Haltiwanger Journal of Biological Chemistry 292 (38), 15964-15973, 2017 | 101 | 2017 |
| A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss E Servián‐Morilla, H Takeuchi, TV Lee, J Clarimon, F Mavillard, ... EMBO molecular medicine 8 (11), 1289-1309, 2016 | 96 | 2016 |
| Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of … H Takeuchi, J Kantharia, MK Sethi, H Bakker, RS Haltiwanger Journal of Biological Chemistry 287 (41), 33934-33944, 2012 | 96 | 2012 |
| O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation J Du, H Takeuchi, C Leonhard-Melief, KR Shroyer, M Dlugosz, ... Developmental biology 346 (1), 25-38, 2010 | 95 | 2010 |
| Peters plus syndrome mutations disrupt a noncanonical ER quality-control mechanism D Vasudevan, H Takeuchi, SS Johar, E Majerus, RS Haltiwanger Current biology 25 (3), 286-295, 2015 | 94 | 2015 |
| Diverse glycosylation of MUC1 and MUC2: potential significance in tumor immunity T Irimura, K Denda, S Iida, H Takeuchi, K Kato The journal of biochemistry 126 (6), 975-986, 1999 | 92 | 1999 |
| Molecular cloning of a xylosyltransferase that transfers the second xylose to O-glucosylated epidermal growth factor repeats of notch MK Sethi, FFR Buettner, A Ashikov, VB Krylov, H Takeuchi, NE Nifantiev, ... Journal of Biological Chemistry 287 (4), 2739-2748, 2012 | 91 | 2012 |
| Role of glycosylation of Notch in development H Takeuchi, RS Haltiwanger Seminars in cell & developmental biology 21 (6), 638-645, 2010 | 91 | 2010 |
| Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase H Takeuchi, RC Fernández-Valdivia, DS Caswell, A Nita-Lazar, NA Rana, ... Proceedings of the National Academy of Sciences 108 (40), 16600-16605, 2011 | 88 | 2011 |
| Two novel protein O-glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling H Takeuchi, M Schneider, DB Williamson, A Ito, M Takeuchi, PA Handford, ... Proceedings of the National Academy of Sciences 115 (36), E8395-E8402, 2018 | 80 | 2018 |
