Sialidase significance for cancer progression T Miyagi, K Takahashi, K Hata, K Shiozaki, K Yamaguchi Glycoconjugate journal 29 (8), 567-577, 2012 | 131 | 2012 |
Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4 K Shiozaki, K Yamaguchi, K Takahashi, S Moriya, T Miyagi Journal of Biological Chemistry 286 (24), 21052-21061, 2011 | 91 | 2011 |
Plasma membrane-associated sialidase (NEU3) regulates progression of prostate cancer to androgen-independent growth through modulation of androgen receptor signaling S Kawamura, I Sato, T Wada, K Yamaguchi, Y Li, D Li, X Zhao, S Ueno, ... Cell Death & Differentiation 19 (1), 170-179, 2012 | 74 | 2012 |
Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease V Seyrantepe, SA Demir, ZK Timur, J Von Gerichten, C Marsching, ... Experimental neurology 299, 26-41, 2018 | 66 | 2018 |
Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides X Pan, C De Britto Pará De Aragão, JP Velasco‐Martin, DA Priestman, ... The FASEB Journal 31 (8), 3467-3483, 2017 | 63 | 2017 |
Sialidase NEU4 hydrolyzes polysialic acids of neural cell adhesion molecules and negatively regulates neurite formation by hippocampal neurons K Takahashi, J Mitoma, M Hosono, K Shiozaki, C Sato, K Yamaguchi, ... Journal of Biological Chemistry 287 (18), 14816-14826, 2012 | 58 | 2012 |
ORP2 couples LDL‐cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P2 exchange K Takahashi, K Kanerva, L Vanharanta, L Almeida‐Souza, D Lietha, ... The EMBO journal 40 (14), e106871, 2021 | 40 | 2021 |
Upregulation of sialidase NEU 3 in head and neck squamous cell carcinoma associated with lymph node metastasis K Shiga, K Takahashi, I Sato, K Kato, S Saijo, S Moriya, M Hosono, ... Cancer science 106 (11), 1544-1553, 2015 | 40 | 2015 |
Increased sialidase activity in serum of cancer patients: Identification of sialidase and inhibitor activities in human serum K Hata, T Tochigi, I Sato, S Kawamura, K Shiozaki, T Wada, K Takahashi, ... Cancer science 106 (4), 383-389, 2015 | 40 | 2015 |
Sialidase NEU 3 contributes neoplastic potential on colon cancer cells as a key modulator of gangliosides by regulating W nt signaling K Takahashi, M Hosono, I Sato, K Hata, T Wada, K Yamaguchi, K Nitta, ... International journal of cancer 137 (7), 1560-1573, 2015 | 39 | 2015 |
ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol A Koponen, A Arora, K Takahashi, H Kentala, AM Kivelä, E Jääskeläinen, ... Biochimie 158, 90-101, 2019 | 38 | 2019 |
Biological and pathological roles of ganglioside sialidases T Miyagi, K Takahashi, K Yamamoto, K Shiozaki, K Yamaguchi Progress in molecular biology and translational science 156, 121-150, 2018 | 36 | 2018 |
Sialic acid-binding lectin (leczyme) induces apoptosis to malignant mesothelioma and exerts synergistic antitumor effects with TRAIL T Tatsuta, M Hosono, K Takahashi, T Omoto, Y Kariya, S Sugawara, ... International journal of oncology 44 (2), 377-384, 2014 | 30 | 2014 |
Phosphatidic acid‐mediated activation and translocation to the cell surface of sialidase NEU3, promoting signaling for cell migration K Shiozaki, K Takahashi, M Hosono, K Yamaguchi, K Hata, M Shiozaki, ... The FASEB Journal 29 (5), 2099-2111, 2015 | 26 | 2015 |
Sialidase NEU3 defines invasive potential of human glioblastoma cells by regulating calpain-mediated proteolysis of focal adhesion proteins K Takahashi, S Proshin, K Yamaguchi, Y Yamashita, R Katakura, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (11), 2778-2788, 2017 | 25 | 2017 |
Potentiation of epidermal growth factor-mediated oncogenic transformation by sialidase NEU3 leading to Src activation K Yamamoto, K Takahashi, K Shiozaki, K Yamaguchi, S Moriya, ... PLoS One 10 (3), e0120578, 2015 | 24 | 2015 |
Altered expression of sialidases in human cancer T Miyagi, K Takahashi, S Moriya, K Hata, K Yamamoto, T Wada, ... Biochemical Roles of Eukaryotic Cell Surface Macromolecules, 257-267, 2012 | 21 | 2012 |
Cancer-selective induction of apoptosis by leczyme T Tatsuta, S Sugawara, K Takahashi, Y Ogawa, M Hosono, K Nitta Frontiers in oncology 4, 139, 2014 | 20 | 2014 |
Leczyme: a new candidate drug for cancer therapy T Tatsuta, S Sugawara, K Takahashi, Y Ogawa, M Hosono, K Nitta BioMed research international 2014, 2014 | 19 | 2014 |
Plasma membrane-associated sialidase confers cancer initiation, promotion and progression T Miyagi, K Takahashi, K Shiozaki, K Yamaguchi, M Hosono Biochemical Roles of Eukaryotic Cell Surface Macromolecules, 139-145, 2015 | 14 | 2015 |