Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A VG Sankaran, TF Menne, J Xu, TE Akie, G Lettre, B Van Handel, ... Science 322 (5909), 1839-1842, 2008 | 1031 | 2008 |
Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells TS Park, Z Galic, AE Conway, A Lindgren, BJ Van Handel, M Magnusson, ... Stem cells 27 (4), 783-795, 2009 | 327 | 2009 |
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration M Patterson, L Barske, B Van Handel, CD Rau, P Gan, A Sharma, ... Nature genetics 49 (9), 1346-1353, 2017 | 288 | 2017 |
Genetic variability overrides the impact of parental cell type and determines iPSC differentiation potential A Kyttälä, R Moraghebi, C Valensisi, J Kettunen, C Andrus, ... Stem cell reports 6 (2), 200-212, 2016 | 247 | 2016 |
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis J Xu, Z Shao, K Glass, DE Bauer, L Pinello, B Van Handel, S Hou, ... Developmental cell 23 (4), 796-811, 2012 | 231 | 2012 |
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium B Van Handel, A Montel-Hagen, R Sasidharan, H Nakano, R Ferrari, ... Cell 150 (3), 590-605, 2012 | 178 | 2012 |
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs MR Hicks, J Hiserodt, K Paras, W Fujiwara, A Eskin, M Jan, H Xi, ... Nature cell biology 20 (1), 46-57, 2018 | 167 | 2018 |
Defining the nature of human pluripotent stem cell progeny M Patterson, DN Chan, I Ha, D Case, Y Cui, BV Handel, HKA Mikkola, ... Cell research 22 (1), 178-193, 2012 | 166 | 2012 |
CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis F Hall-Glenn, RA De Young, BL Huang, B van Handel, JJ Hofmann, ... PloS one 7 (2), e30562, 2012 | 156 | 2012 |
Haemogenic endocardium contributes to transient definitive haematopoiesis H Nakano, X Liu, A Arshi, Y Nakashima, B Van Handel, R Sasidharan, ... Nature communications 4 (1), 1564, 2013 | 155 | 2013 |
In vivo human somitogenesis guides somite development from hPSCs H Xi, W Fujiwara, K Gonzalez, M Jan, S Liebscher, B Van Handel, ... Cell reports 18 (6), 1573-1585, 2017 | 129 | 2017 |
The first trimester human placenta is a site for terminal maturation of primitive erythroid cells B Van Handel, SL Prashad, N Hassanzadeh-Kiabi, A Huang, ... Blood, The Journal of the American Society of Hematology 116 (17), 3321-3330, 2010 | 126 | 2010 |
Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells L Wu, C Bluguermann, L Kyupelyan, B Latour, S Gonzalez, S Shah, ... Stem cell reports 1 (6), 575-589, 2013 | 123 | 2013 |
A human skeletal muscle atlas identifies the trajectories of stem and progenitor cells across development and from human pluripotent stem cells H Xi, J Langerman, S Sabri, P Chien, CS Young, S Younesi, M Hicks, ... Cell stem cell 27 (1), 158-176. e10, 2020 | 113 | 2020 |
Hepatic leukemia factor maintains quiescence of hematopoietic stem cells and protects the stem cell pool during regeneration K Komorowska, A Doyle, M Wahlestedt, A Subramaniam, S Debnath, ... Cell reports 21 (12), 3514-3523, 2017 | 93 | 2017 |
In vivo mapping of notch pathway activity in normal and stress hematopoiesis P Oh, C Lobry, J Gao, A Tikhonova, E Loizou, J Manent, B Van Handel, ... Cell stem cell 13 (2), 190-204, 2013 | 93 | 2013 |
Recapitulation of the embryonic cardiovascular progenitor cell niche K Schenke-Layland, A Nsair, B Van Handel, E Angelis, JM Gluck, ... Biomaterials 32 (11), 2748-2756, 2011 | 84 | 2011 |
Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence T Org, D Duan, R Ferrari, A MontelHagen, B Van Handel, MA Kerényi, ... The EMBO journal 34 (6), 759-777, 2015 | 80 | 2015 |
c-Met-dependent multipotent labyrinth trophoblast progenitors establish placental exchange interface M Ueno, LK Lee, A Chhabra, YJ Kim, R Sasidharan, B Van Handel, ... Developmental cell 27 (4), 373-386, 2013 | 79 | 2013 |
Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells X Huang, E Gschweng, B Van Handel, D Cheng, HKA Mikkola, ON Witte Blood, The Journal of the American Society of Hematology 117 (7), 2157-2165, 2011 | 79 | 2011 |