Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility H Xiao, M Lu, TY Lin, Z Chen, G Chen, WC Wang, T Marin, T Shentu, ... Circulation 128 (6), 632-642, 2013 | 262 | 2013 |
TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases G Chen, N Khalil Respiratory research 7, 1-10, 2006 | 235 | 2006 |
Release of biologically active TGF-β from airway smooth muscle cells induces autocrine synthesis of collagen A Coutts, G Chen, N Stephens, S Hirst, D Douglas, T Eichholtz, N Khalil American Journal of Physiology-Lung Cellular and Molecular Physiology 280 (5 …, 2001 | 162 | 2001 |
A high dose of ionizing radiation induces tissue-specific activation of nuclear factor-κB in vivo D Zhou, SA Brown, T Yu, G Chen, S Barve, BC Kang, JS Thompson Radiation research 151 (6), 703-709, 1999 | 102 | 1999 |
Effects of NF-κB1 (p50) targeted gene disruption on ionizing radiation-induced NF-κB activation and TNFα, IL-1α, IL-1β and IL-6 mRNA expression in vivo D Zhou, T Yu, G Chen, SA Brown, Z Yu, MP Mattson, JS Thompson International journal of radiation biology 77 (7), 763-772, 2001 | 92* | 2001 |
Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer K Chellappa, P Deol, JR Evans, LM Vuong, G Chen, N Briançon, ... Elife 5, e10903, 2016 | 79 | 2016 |
GM-CSF increases airway smooth muscle cell connective tissue expression by inducing TGF-β receptors G Chen, G Grotendorst, T Eichholtz, N Khalil American Journal of Physiology-Lung Cellular and Molecular Physiology, 2003 | 69 | 2003 |
Comparison of RELMα and RELMβ single-and double-gene-deficient mice reveals that RELMα expression dictates inflammation and worm expulsion in hookworm infection G Chen, SH Wang, JC Jang, JI Odegaard, MG Nair Infection and immunity 84 (4), 1100-1111, 2016 | 58 | 2016 |
Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden JC Jang, G Chen, SH Wang, MA Barnes, JI Chung, M Camberis, ... PLoS pathogens 11 (1), e1004579, 2015 | 58 | 2015 |
Bcr and Abr cooperate in negatively regulating acute inflammatory responses JM Cunnick, S Schmidhuber, G Chen, M Yu, SJ Yi, YJ Cho, V Kaartinen, ... Molecular and cellular biology, 2009 | 51 | 2009 |
Induction of colonic M cells during intestinal inflammation KM Bennett, EA Parnell, C Sanscartier, S Parks, G Chen, MG Nair, DD Lo The American journal of pathology 186 (5), 1166-1179, 2016 | 50 | 2016 |
Ixodes scapularis saliva mitigates inflammatory cytokine secretion during Anaplasma phagocytophilum stimulation of immune cells G Chen, MS Severo, M Sohail, OS Sakhon, SK Wikel, M Kotsyfakis, ... Parasites & vectors 5, 1-10, 2012 | 50 | 2012 |
The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection G Chen, X Wang, MS Severo, OS Sakhon, M Sohail, LJ Brown, M Sircar, ... Infection and immunity 82 (6), 2553-2564, 2014 | 49 | 2014 |
The E3 Ubiquitin Ligase XIAP Restricts Anaplasma phagocytophilum Colonization of Ixodes scapularis Ticks MS Severo, A Choy, KD Stephens, OS Sakhon, G Chen, DWD Chung, ... The Journal of infectious diseases 208 (11), 1830-1840, 2013 | 49 | 2013 |
Airway hyperresponsiveness to cigarette smoke in ovalbumin-sensitized guinea pigs ZX Wu, D Zhou, G Chen, LY Lee American journal of respiratory and critical care medicine 161 (1), 73-80, 2000 | 48 | 2000 |
The inflammasome in host defense G Chen, JHF Pedra Sensors 10 (1), 97-111, 2009 | 42 | 2009 |
Anaplasma phagocytophilum dihydrolipoamide dehydrogenase 1 affects host-derived immunopathology during microbial colonization G Chen, MS Severo, OS Sakhon, A Choy, MJ Herron, RF Felsheim, ... Infection and immunity 80 (9), 3194-3205, 2012 | 34 | 2012 |
Hematopoietic cell-derived RELMα regulates hookworm immunity through effects on macrophages HM Batugedara, J Li, G Chen, D Lu, JJ Patel, JC Jang, KC Radecki, ... Journal of leukocyte biology 104 (4), 855-869, 2018 | 30 | 2018 |
In vitro wounding of airway smooth muscle cell monolayers increases expression of TGF-β receptors G Chen, N Khalil Respiratory physiology & neurobiology 132 (3), 341-346, 2002 | 29 | 2002 |
Mechanism and function of antiviral RNA interference in mice Q Han, G Chen, J Wang, D Jee, WX Li, EC Lai, SW Ding MBio 11 (4), 10.1128/mbio. 03278-19, 2020 | 24 | 2020 |