Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117 M Caskey, F Klein, JCC Lorenzi, MS Seaman, AP West Jr, N Buckley, ... Nature 522 (7557), 487, 2015 | 807 | 2015 |
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice F Klein, A Halper-Stromberg, JA Horwitz, H Gruell, JF Scheid, ... Nature 492 (7427), 118, 2012 | 577 | 2012 |
HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption JF Scheid, JA Horwitz, Y Bar-On, EF Kreider, CL Lu, JCC Lorenzi, ... Nature 535 (7613), 556, 2016 | 477 | 2016 |
A genetically humanized mouse model for hepatitis C virus infection M Dorner, JA Horwitz, JB Robbins, WT Barry, Q Feng, K Mu, CT Jones, ... Nature 474 (7350), 208, 2011 | 442 | 2011 |
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice A Halper-Stromberg, CL Lu, F Klein, JA Horwitz, S Bournazos, L Nogueira, ... Cell 158 (5), 989-999, 2014 | 415 | 2014 |
Enhanced clearance of HIV-1–infected cells by broadly neutralizing antibodies against HIV-1 in vivo CL Lu, DK Murakowski, S Bournazos, T Schoofs, D Sarkar, ... Science 352 (6288), 1001-1004, 2016 | 360 | 2016 |
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice JA Horwitz, A Halper-Stromberg, H Mouquet, AD Gitlin, A Tretiakova, ... Proceedings of the National Academy of Sciences 110 (41), 16538-16543, 2013 | 292 | 2013 |
Completion of the entire hepatitis C virus life cycle in genetically humanized mice M Dorner, JA Horwitz, BM Donovan, RN Labitt, WC Budell, T Friling, ... Nature 501 (7466), 237, 2013 | 261 | 2013 |
Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission M Malbec, F Porrot, R Rua, J Horwitz, F Klein, A Halper-Stromberg, ... Journal of Experimental Medicine 210 (13), 2813-2821, 2013 | 194 | 2013 |
Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA JCC Lorenzi, YZ Cohen, LB Cohn, EF Kreider, JP Barton, GH Learn, ... Proceedings of the National Academy of Sciences 113 (49), E7908-E7916, 2016 | 192 | 2016 |
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller NT Freund, H Wang, L Scharf, L Nogueira, JA Horwitz, Y Bar-On, ... Science translational medicine 9 (373), eaal2144, 2017 | 166 | 2017 |
Non-neutralizing antibodies alter the course of HIV-1 infection in vivo JA Horwitz, Y Bar-On, CL Lu, D Fera, AAK Lockhart, JCC Lorenzi, ... Cell 170 (4), 637-648. e10, 2017 | 150 | 2017 |
Computational analysis of anti–HIV-1 antibody neutralization panel data to identify potential functional epitope residues AP West, L Scharf, J Horwitz, F Klein, MC Nussenzweig, PJ Bjorkman Proceedings of the National Academy of Sciences 110 (26), 10598-10603, 2013 | 129 | 2013 |
Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies R Diskin, F Klein, JA Horwitz, A Halper-Stromberg, DN Sather, ... Journal of Experimental Medicine 210 (6), 1235-1249, 2013 | 104 | 2013 |
Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants F Klein, L Nogueira, Y Nishimura, G Phad, AP West, A Halper-Stromberg, ... Journal of Experimental Medicine 211 (12), 2361-2372, 2014 | 100 | 2014 |
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice E Billerbeck, JA Horwitz, RN Labitt, BM Donovan, K Vega, WC Budell, ... The Journal of Immunology 191 (4), 1753-1764, 2013 | 75 | 2013 |
Biological performance of biodegradable amino acid‐based poly(ester amide)s: Endothelial cell adhesion and inflammation in vitro JA Horwitz, KM Shum, JC Bodle, MX Deng, CC Chu, CA Reinhart‐King Journal of Biomedical Materials Research Part A 95 (2), 371-380, 2010 | 68 | 2010 |
Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines A Vogt, MA Scull, T Friling, JA Horwitz, BM Donovan, M Dorner, G Gerold, ... Virology 444 (1-2), 1-11, 2013 | 58 | 2013 |
A new glycan-dependent CD4-binding site neutralizing antibody exerts pressure on HIV-1 in vivo NT Freund, JA Horwitz, L Nogueira, SA Sievers, L Scharf, JF Scheid, ... PLoS pathogens 11 (10), e1005238, 2015 | 55 | 2015 |
Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice MA Scull, C Shi, YP de Jong, G Gerold, M Ries, M von Schaewen, ... Hepatology 62 (1), 57-67, 2015 | 28 | 2015 |