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Joshua Horwitz
Joshua Horwitz
Postdoc, HMS
Verified email at crystal.harvard.edu
Title
Cited by
Cited by
Year
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
M Caskey, F Klein, JCC Lorenzi, MS Seaman, AP West Jr, N Buckley, ...
Nature 522 (7557), 487, 2015
8072015
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
F Klein, A Halper-Stromberg, JA Horwitz, H Gruell, JF Scheid, ...
Nature 492 (7427), 118, 2012
5772012
HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption
JF Scheid, JA Horwitz, Y Bar-On, EF Kreider, CL Lu, JCC Lorenzi, ...
Nature 535 (7613), 556, 2016
4772016
A genetically humanized mouse model for hepatitis C virus infection
M Dorner, JA Horwitz, JB Robbins, WT Barry, Q Feng, K Mu, CT Jones, ...
Nature 474 (7350), 208, 2011
4422011
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice
A Halper-Stromberg, CL Lu, F Klein, JA Horwitz, S Bournazos, L Nogueira, ...
Cell 158 (5), 989-999, 2014
4152014
Enhanced clearance of HIV-1–infected cells by broadly neutralizing antibodies against HIV-1 in vivo
CL Lu, DK Murakowski, S Bournazos, T Schoofs, D Sarkar, ...
Science 352 (6288), 1001-1004, 2016
3602016
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
JA Horwitz, A Halper-Stromberg, H Mouquet, AD Gitlin, A Tretiakova, ...
Proceedings of the National Academy of Sciences 110 (41), 16538-16543, 2013
2922013
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
M Dorner, JA Horwitz, BM Donovan, RN Labitt, WC Budell, T Friling, ...
Nature 501 (7466), 237, 2013
2612013
Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission
M Malbec, F Porrot, R Rua, J Horwitz, F Klein, A Halper-Stromberg, ...
Journal of Experimental Medicine 210 (13), 2813-2821, 2013
1942013
Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA
JCC Lorenzi, YZ Cohen, LB Cohn, EF Kreider, JP Barton, GH Learn, ...
Proceedings of the National Academy of Sciences 113 (49), E7908-E7916, 2016
1922016
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
NT Freund, H Wang, L Scharf, L Nogueira, JA Horwitz, Y Bar-On, ...
Science translational medicine 9 (373), eaal2144, 2017
1662017
Non-neutralizing antibodies alter the course of HIV-1 infection in vivo
JA Horwitz, Y Bar-On, CL Lu, D Fera, AAK Lockhart, JCC Lorenzi, ...
Cell 170 (4), 637-648. e10, 2017
1502017
Computational analysis of anti–HIV-1 antibody neutralization panel data to identify potential functional epitope residues
AP West, L Scharf, J Horwitz, F Klein, MC Nussenzweig, PJ Bjorkman
Proceedings of the National Academy of Sciences 110 (26), 10598-10603, 2013
1292013
Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies
R Diskin, F Klein, JA Horwitz, A Halper-Stromberg, DN Sather, ...
Journal of Experimental Medicine 210 (6), 1235-1249, 2013
1042013
Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants
F Klein, L Nogueira, Y Nishimura, G Phad, AP West, A Halper-Stromberg, ...
Journal of Experimental Medicine 211 (12), 2361-2372, 2014
1002014
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice
E Billerbeck, JA Horwitz, RN Labitt, BM Donovan, K Vega, WC Budell, ...
The Journal of Immunology 191 (4), 1753-1764, 2013
752013
Biological performance of biodegradable amino acid‐based poly(ester amide)s: Endothelial cell adhesion and inflammation in vitro
JA Horwitz, KM Shum, JC Bodle, MX Deng, CC Chu, CA Reinhart‐King
Journal of Biomedical Materials Research Part A 95 (2), 371-380, 2010
682010
Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines
A Vogt, MA Scull, T Friling, JA Horwitz, BM Donovan, M Dorner, G Gerold, ...
Virology 444 (1-2), 1-11, 2013
582013
A new glycan-dependent CD4-binding site neutralizing antibody exerts pressure on HIV-1 in vivo
NT Freund, JA Horwitz, L Nogueira, SA Sievers, L Scharf, JF Scheid, ...
PLoS pathogens 11 (10), e1005238, 2015
552015
Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice
MA Scull, C Shi, YP de Jong, G Gerold, M Ries, M von Schaewen, ...
Hepatology 62 (1), 57-67, 2015
282015
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