Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis International IBD Genetics Consortium (IIBDGC), C Agliardi, L Alfredsson, ... Nature genetics 45 (11), 1353-1360, 2013 | 1335 | 2013 |
In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis V Siffrin, H Radbruch, R Glumm, R Niesner, M Paterka, J Herz, ... Immunity 33 (3), 424-436, 2010 | 349 | 2010 |
Multiple sclerosis–candidate mechanisms underlying CNS atrophy V Siffrin, J Vogt, H Radbruch, R Nitsch, F Zipp Trends in neurosciences 33 (4), 202-210, 2010 | 249 | 2010 |
MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4 JT Walsh, S Hendrix, F Boato, I Smirnov, J Zheng, JR Lukens, S Gadani, ... The Journal of clinical investigation 125 (2), 699-714, 2015 | 215 | 2015 |
Neurodegeneration in autoimmune CNS inflammation J Herz, F Zipp, V Siffrin Experimental neurology 225 (1), 9-17, 2010 | 165 | 2010 |
Neurodegeneration in multiple sclerosis: novel treatment strategies F Luessi, V Siffrin, F Zipp Expert Review of Neurotherapeutics 12 (9), 1061-1077, 2012 | 146 | 2012 |
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system U Schulze-Topphoff, A Prat, T Prozorovski, V Siffrin, M Paterka, J Herz, ... Nature medicine 15 (7), 788-793, 2009 | 130 | 2009 |
Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis V Jolivel, F Luessi, J Masri, SHP Kraus, M Hubo, L Poisa-Beiro, S Klebow, ... Brain 136 (4), 1048-1066, 2013 | 123 | 2013 |
Expanding two-photon intravital microscopy to the infrared by means of optical parametric oscillator J Herz, V Siffrin, AE Hauser, AU Brandt, T Leuenberger, H Radbruch, ... Biophysical journal 98 (4), 715-723, 2010 | 113 | 2010 |
Cytotoxic CD8+ T cell–neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death SG Meuth, AM Herrmann, OJ Simon, V Siffrin, N Melzer, S Bittner, ... Journal of Neuroscience 29 (49), 15397-15409, 2009 | 102 | 2009 |
BLBP-expression in astrocytes during experimental demyelination and in human multiple sclerosis lesions M Kipp, S Gingele, F Pott, T Clarner, P van der Valk, B Denecke, L Gan, ... Brain, behavior, and immunity 25 (8), 1554-1568, 2011 | 94 | 2011 |
Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells A Nogai, V Siffrin, K Bonhagen, CF Pfueller, T Hohnstein, ... The Journal of Immunology 175 (2), 959-966, 2005 | 91 | 2005 |
Microglial activation milieu controls regulatory T cell responses F Ebner, C Brandt, P Thiele, D Richter, U Schliesser, V Siffrin, J Schueler, ... The Journal of Immunology 191 (11), 5594-5602, 2013 | 85 | 2013 |
PML risk stratification using anti-JCV antibody index and L-selectin N Schwab, T Schneider-Hohendorf, B Pignolet, M Spadaro, D Görlich, ... Multiple Sclerosis Journal 22 (8), 1048-1060, 2016 | 80 | 2016 |
Parallelized TCSPC for dynamic intravital fluorescence lifetime imaging: quantifying neuronal dysfunction in neuroinflammation JL Rinnenthal, C Börnchen, H Radbruch, V Andresen, A Mossakowski, ... PloS one 8 (4), e60100, 2013 | 78 | 2013 |
Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization V Siffrin, AU Brandt, H Radbruch, J Herz, N Boldakowa, T Leuenberger, ... Brain 132 (5), 1247-1258, 2009 | 78 | 2009 |
In vivo and in vitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity D Luchtman, R Gollan, E Ellwardt, J Birkenstock, K Robohm, V Siffrin, ... Journal of neurochemistry 136 (5), 971-980, 2016 | 67 | 2016 |
New candidates for CD4 T cell pathogenicity in experimental neuroinflammation and multiple sclerosis N Hoppmann, C Graetz, M Paterka, L Poisa-Beiro, C Larochelle, M Hasan, ... Brain 138 (4), 902-917, 2015 | 65 | 2015 |
Gatekeeper role of brain antigen‐presenting CD11c+ cells in neuroinflammation M Paterka, V Siffrin, JO Voss, J Werr, N Hoppmann, R Gollan, P Belikan, ... The EMBO journal 35 (1), 89-101, 2016 | 53 | 2016 |
In vivo imaging of lymphocytes in the CNS reveals different behaviour of naïve T cells in health and autoimmunity J Herz, M Paterka, RA Niesner, AU Brandt, V Siffrin, T Leuenberger, ... Journal of neuroinflammation 8, 1-12, 2011 | 53 | 2011 |