| Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space EK Makowski, PC Kinnunen, J Huang, L Wu, MD Smith, T Wang, ... Nature communications 13 (1), 3788, 2022 | 71 | 2022 |
| Toward drug-like multispecific antibodies by design MS Sawant, CN Streu, L Wu, PM Tessier International journal of molecular sciences 21 (20), 7496, 2020 | 48 | 2020 |
| Unique impacts of methionine oxidation, tryptophan oxidation, and asparagine deamidation on antibody stability and aggregation ME Alam, TR Slaney, L Wu, TK Das, S Kar, GV Barnett, A Leone, ... Journal of Pharmaceutical Sciences 109 (1), 656-669, 2020 | 44 | 2020 |
| Physicochemical rules for identifying monoclonal antibodies with drug-like specificity Y Zhang, L Wu, P Gupta, AA Desai, MD Smith, LA Rabia, SD Ludwig, ... Molecular pharmaceutics 17 (7), 2555-2569, 2020 | 43 | 2020 |
| Discovery-stage identification of drug-like antibodies using emerging experimental and computational methods EK Makowski, L Wu, P Gupta, PM Tessier MAbs 13 (1), 1895540, 2021 | 34 | 2021 |
| Highly sensitive detection of antibody nonspecific interactions using flow cytometry EK Makowski, L Wu, AA Desai, PM Tessier MAbs 13 (1), 1951426, 2021 | 25 | 2021 |
| Ultradilute measurements of self-association for the identification of antibodies with favorable high-concentration solution properties CG Starr, EK Makowski, L Wu, B Berg, JS Kingsbury, YR Gokarn, ... Molecular Pharmaceutics 18 (7), 2744-2753, 2021 | 23 | 2021 |
| Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning EK Makowski, T Wang, JM Zupancic, J Huang, L Wu, JS Schardt, ... Nature Biomedical Engineering 8 (1), 45-56, 2024 | 11 | 2024 |
| Reduction of monoclonal antibody viscosity using interpretable machine learning EK Makowski, HT Chen, T Wang, L Wu, J Huang, M Mock, P Underhill, ... Mabs 16 (1), 2303781, 2024 | 1 | 2024 |
| Antibody Affinity and Specificity Co-Optimization Via Machine Learning P Kinnunen, EK Makowski, L Wu, J Huang, JJ Linderman, PM Tessier 2022 AIChE Annual Meeting, 2022 | | 2022 |
