Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2) M Grieben, ACW Pike, CA Shintre, E Venturi, S El-Ajouz, A Tessitore, ... Nature structural & molecular biology 24 (2), 114-122, 2017 | 190 | 2017 |
Cysteine substitution mutagenesis and the effects of methanethiosulfonate reagents at P2X2 and P2X4 receptors support a core common mode of ATP action at P2X receptors JA Roberts, HR Digby, M Kara, S El Ajouz, MJ Sutcliffe, RJ Evans Journal of biological chemistry 283 (29), 20126-20136, 2008 | 73 | 2008 |
Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel JA Roberts, RC Allsopp, S El Ajouz, C Vial, R Schmid, MT Young, ... Proceedings of the National Academy of Sciences 109 (12), 4663-4667, 2012 | 64 | 2012 |
Cysteine scanning mutagenesis (residues Glu52–Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating RC Allsopp, S El Ajouz, R Schmid, RJ Evans Journal of Biological Chemistry 286 (33), 29207-29217, 2011 | 51 | 2011 |
Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine‐rich loop S El‐Ajouz, D Ray, RC Allsopp, RJ Evans British journal of pharmacology 165 (2), 390-400, 2012 | 50 | 2012 |
Dampened activity of ryanodine receptor channels in mutant skeletal muscle lacking TRIC‐A S El‐Ajouz, E Venturi, K Witschas, M Beech, AD Wilson, C Lindsay, ... The Journal of Physiology 595 (14), 4769-4784, 2017 | 20 | 2017 |
Enhanced activity of multiple TRIC‐B channels: an endoplasmic reticulum/sarcoplasmic reticulum mechanism to boost counterion currents F O'Brien, D Eberhardt, K Witschas, S El‐Ajouz, T Iida, M Nishi, ... The Journal of Physiology 597 (10), 2691-2705, 2019 | 11 | 2019 |
Differential Effects of Temperature and Lipids on the Gating of RyR and SR K+ Channels S El-Ajouz, E Venturi, R Sitsapesan Biophysical Journal 110 (3), 266a, 2016 | 1 | 2016 |
Dampened Activity of Single Ryanodine Receptor Channels in Mice Devoid of TRIC-A K Witschas, F O'Brien, E Venturi, S El-Ajouz, M Beech, D Eberhardt, T Iida, ... Biophysical Journal 110 (3), 266a, 2016 | 1 | 2016 |
Cooperative Gating Among Ion-Channel Species in Junctional Sarcoplasmic Reticulum E Venturi, F O'Brien, D Eberhardt, K Witschas, S El-Ajouz, T Iida, ... Biophysical Journal 116 (3), 521a, 2019 | | 2019 |
Single ryanodine receptor channels from the skeletal muscle of TRIC-A knockout mice show reduced activation by Mg2+ ATP K Witschas, S El-Ajouz, E Venturi, M Beech, F O'Brien, D Eberhardt, T Iida, ... Physiology 2016: joint meeting of the American Physiological Society and The …, 2016 | | 2016 |
Cardiac and skeletal sarcoplasmic reticulum K+ channels from TRIC-A knockout mice show distinct gating characteristics to those derived from wild type mice D Eberhardt, F O'Brien, E Venturi, K Witschas, S El-Ajouz, T Iida, M Nishi, ... Physiology 2016: joint meeting of the American Physiological Society and The …, 2016 | | 2016 |
Understanding the Molecular Gates of KirBac3. 1 S El-Ajouz, AP Hill, JM Gulbis, JI Vandenberg Biophysical Journal 104 (2), 128a, 2013 | | 2013 |
Molecular basis of antagonist action at the P2X1 receptor S El-Ajouz University of Leicester, 2011 | | 2011 |
Enhanced activity of multiple TRIC-B channels; an ER/SR mechanism to boost counterion currents F O’Brien, D Eberhardt, K Witschas, S El-Ajouz, T Iida, M Nishi, ... | | |