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Simin Zheng
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CtIP promotes microhomology-mediated alternative end joining during class-switch recombination
M Lee-Theilen, AJ Matthews, D Kelly, S Zheng, J Chaudhuri
Nature structural & molecular biology 18 (1), 75-79, 2011
2192011
Non-coding RNA generated following lariat debranching mediates targeting of AID to DNA
S Zheng, BQ Vuong, B Vaidyanathan, JY Lin, FT Huang, J Chaudhuri
Cell 161 (4), 762-773, 2015
2052015
Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair
AJ Matthews, S Zheng, LJ DiMenna, J Chaudhuri
Advances in immunology 122, 1-57, 2014
1732014
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA
U Nowak, AJ Matthews, S Zheng, J Chaudhuri
Nature immunology 12 (2), 160-166, 2011
1322011
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
JSY Ho, BWY Mok, L Campisi, T Jordan, S Yildiz, S Parameswaran, ...
Cell 184 (10), 2618-2632. e17, 2021
832021
Hybrid gene origination creates human-virus chimeric proteins during infection
JSY Ho, M Angel, Y Ma, E Sloan, G Wang, C Martinez-Romero, ...
Cell 181 (7), 1502-1517. e23, 2020
402020
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
JSY Ho, F Di Tullio, M Schwarz, D Low, D Incarnato, F Gay, T Tabaglio, ...
Elife 10, e59654, 2021
322021
A quantitative genetic interaction map of HIV infection
DE Gordon, A Watson, A Roguev, S Zheng, GM Jang, J Kane, J Xu, ...
Molecular cell 78 (2), 197-209. e7, 2020
212020
Anti-estrogenic mechanism of unliganded progesterone receptor isoform B in breast cancer cells
ZY Zheng, SM Zheng, BH Bay, SE Aw, V CL Lin
Breast cancer research and treatment 110, 111-125, 2008
202008
DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells
JY Lim, SH Duttke, TS Baker, J Lee, KJ Gambino, NJ Venturini, JSY Ho, ...
Journal of Experimental Medicine 218 (7), e20202733, 2021
132021
NME proteins regulate class switch recombination
S Zheng, A Kusnadi, JE Choi, BQ Vuong, D Rhodes, J Chaudhuri
FEBS letters 593 (1), 80-87, 2019
122019
Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models
JS Yuin Ho, B Wing-Yee Mok, L Campisi, T Jordan, S Yildiz, ...
bioRxiv, 2020.12. 01.404483, 2020
82020
Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
N Zhao, JSY Ho, F Meng, S Zheng, AP Kurland, L Tian, M Rea-Moreno, ...
Cell Host & Microbe 31 (7), 1154-1169. e10, 2023
32023
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation
D Torre, YS Fstkchyan, JSY Ho, Y Cheon, RS Patel, EJ Degrace, ...
Molecular cell 83 (23), 4255-4271. e9, 2023
22023
Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches
E Sible, S Zheng, JE Choi, BQ Vuong
JoVE (Journal of Visualized Experiments), e61551, 2021
12021
The uncharacterized SANT and BTB domain-containing protein SANBR inhibits class switch recombination
S Zheng, AJ Matthews, N Rahman, K Herrick-Reynolds, E Sible, JE Choi, ...
Journal of Biological Chemistry 296, 2021
12021
A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification
JZ Zhou, B Huang, B Pei, GW Sun, MD Pawlitz, W Zhang, X Li, ...
bioRxiv, 2024
2024
The DEAH-box helicase RHAU regulates immunoglobulin class switch recombination
T Thavornwatanayong, S Zheng, SJ Guillaume, BQ Vuong
The Journal of Immunology 208 (1_Supplement), 112.08-112.08, 2022
2022
KIAA1841, a novel SANT and BTB domain-containing protein, inhibits class switch recombination
S Zheng, AJ Matthews, N Rahman, K Herrick-Reynolds, JE Choi, E Sible, ...
bioRxiv, 2020.08. 12.247809, 2020
2020
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain prostate cancer cell fitness
JSY Ho, D Low, M Schwarz, D Incarnato, F Gay, T Tabaglio, J Zhang, ...
bioRxiv, 2020.06. 17.157537, 2020
2020
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