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RICHARD KURUPI
RICHARD KURUPI
Verified email at wustl.edu
Title
Cited by
Cited by
Year
Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets
JM Balko, JM Giltnane, K Wang, LJ Schwarz, CD Young, RS Cook, ...
Cancer discovery 4 (2), 232-245, 2014
5482014
Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer
JM Balko, LJ Schwarz, NE Bhola, R Kurupi, P Owens, TW Miller, H Gómez, ...
Cancer research 73 (20), 6346-6358, 2013
1602013
Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110α inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers
JT Garrett, CR Sutton, R Kurupi, CU Bialucha, SA Ettenberg, SD Collins, ...
Cancer research 73 (19), 6013-6023, 2013
922013
MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis
KV Floros, JY Cai, S Jacob, R Kurupi, CK Fairchild, M Shende, CM Coon, ...
Cancer research 81 (7), 1896-1908, 2021
882021
Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma
TL Lochmann, KM Powell, J Ham, KV Floros, DAR Heisey, RIJ Kurupi, ...
Science translational medicine 10 (441), eaao4680, 2018
852018
High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
J Cai, S Jacob, R Kurupi, KM Dalton, C Coon, P Greninger, RK Egan, ...
Cell reports 40 (4), 2022
142022
Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma
KM Dalton, TL Lochmann, KV Floros, ML Calbert, R Kurupi, GT Stein, ...
Proceedings of the National Academy of Sciences 118 (13), e2009620118, 2021
142021
Venetoclax-based Rational Combinations are Effective in Models of MYCN-amplified Neuroblastoma
KM Dalton, K Krytska, TL Lochmann, R Sano, C Casey, A D'Aulerio, ...
Molecular cancer therapeutics 20 (8), 1400-1411, 2021
122021
Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors
KV Floros, S Jacob, R Kurupi, CK Fairchild, B Hu, M Puchalapalli, ...
Cell Death & Disease 12 (2), 179, 2021
122021
Pharmaceutical interference of the EWS-FLI1–driven transcriptome by cotargeting H3K27ac and RNA polymerase activity in Ewing sarcoma
DAR Heisey, S Jacob, TL Lochmann, R Kurupi, MS Ghotra, ML Calbert, ...
Molecular Cancer Therapeutics 20 (10), 1868-1879, 2021
102021
Pharmacologic inhibition of SHP2 blocks both PI3K and MEK signaling in low-epiregulin HNSCC via GAB1
R Kurupi, KV Floros, S Jacob, AT Chawla, J Cai, B Hu, M Puchalapalli, ...
Cancer research communications 2 (9), 1061-1074, 2022
42022
Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov 4 (2): 232–245
JM Balko, JM Giltnane, K Wang, LJ Schwarz, CD Young, RS Cook, ...
CD-13-0286, 2014
42014
Pharmacological targeting of SUMOylation leads to cBAF complex stabilization and disruption of the synovial sarcoma signature
KV Floros, J Li, JL Roberts, R Kurupi, CK Fairchild, B Hu, Y Xing, ...
Cancer Research 84 (6_Supplement), 7071-7071, 2024
2024
Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18:: SSX transcriptome in Synovial Sarcoma
KV Floros, CK Fairchild Jr, J Li, K Zhang, JL Roberts, R Kurupi, B Hu, ...
bioRxiv, 2024.04. 25.591023, 2024
2024
Epithelial-mesenchymal transition and resistance to EGFR inhibitors
S Jacob, R Kurupi, AC Faber
Overcoming Resistance to EGFR Inhibitors in EGFR-Mutant NSCLC, 105-124, 2023
2023
MYCN-amplified neuroblastoma is addicted to iron and vulnerable to ferroptosis
KV Floros, MO Johnson-Berro, R Kurupi, CK Fairchild, K Dalton, B Hu, ...
Cancer Research 82 (12_Supplement), 362-362, 2022
2022
SHP2 inhibition-based combination targeted therapies for molecularly defined subgroups of HNSCC patients
R Kurupi
2022
Abstract PO-024: Catastrophic ATP loss underlines a metabolic combination therapy tailored for MYCN-amplified neuroblastoma
KM Powell, TL Lochmann, KV Floros, ML Calbert, R Kurupi, GT Stein, ...
Cancer Research 80 (23_Supplement), PO-024-PO-024, 2020
2020
Breast Cancer Classification According to Immunohistochemistry Markers: Subtypes and Association With Clinicopathologic Variables in a Peruvian Hospital Database
C Vigil Gonzales, R Velarde, SP Neciosup, M León, H Gómez Moreno, ...
Elsevier Inc., 2010
2010
Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer
R Kurupi, HL Gómez Moreno, CL Arteaga
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Articles 1–20