| A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens J Sun, MD Masterman-Smith, NA Graham, J Jiao, J Mottahedeh, DR Laks, ... Cancer research 70 (15), 6128-6138, 2010 | 118 | 2010 |
| Allosteric inhibition of ubiquitin-like modifications by a class of inhibitor of SUMO-activating enzyme YJ Li, L Du, J Wang, R Vega, TD Lee, Y Miao, G Aldana-Masangkay, ... Cell chemical biology 26 (2), 278-288. e6, 2019 | 48 | 2019 |
| Photosensitive Ru (II) complexes as inhibitors of the major human drug metabolizing enzyme CYP3A4 N Toupin, SJ Steinke, S Nadella, A Li, TN Rohrabaugh Jr, ER Samuels, ... Journal of the American Chemical Society 143 (24), 9191-9205, 2021 | 44 | 2021 |
| Inhibition of human CYP3A4 by rationally designed ritonavir-like compounds: Impact and interplay of the side group functionalities ER Samuels, I Sevrioukova Molecular pharmaceutics 15 (1), 279-288, 2018 | 27 | 2018 |
| Rational design of CYP3A4 inhibitors: a one-atom linker elongation in ritonavir-like compounds leads to a marked improvement in the binding strength ER Samuels, IF Sevrioukova International journal of molecular sciences 22 (2), 852, 2021 | 22 | 2021 |
| An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4 ER Samuels, IF Sevrioukova Bioorganic & medicinal chemistry 28 (6), 115349, 2020 | 19 | 2020 |
| Structure–Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the … ER Samuels, I Sevrioukova Biochemistry 58 (15), 2077-2087, 2019 | 16 | 2019 |
| Quantitative 1H NMR analysis of a difficult drug substance and its exo-isomer as hydrochloride salts using alkaline deuterated methanol ER Samuels, T Wang Journal of Pharmaceutical and Biomedical Analysis 187, 113338, 2020 | 11 | 2020 |
| Direct synthesis of α-thio aromatic acids from aromatic amino acids ER Samuels, IF Sevrioukova Tetrahedron letters 59 (12), 1140-1142, 2018 | 10 | 2018 |
| Effective synthesis of 3′-deoxy-3′-azido nucleosides for antiviral and antisense ribonucleic guanidine (RNG) applications ER Samuels, J McNary, M Aguilar, AM Awad Nucleosides, Nucleotides and Nucleic Acids 32 (3), 109-123, 2013 | 8 | 2013 |
| Interaction of CYP3A4 with Rationally Designed Ritonavir Analogues: Impact of Steric Constraints Imposed on the Heme-Ligating Group and the End-Pyridine Attachment ER Samuels, IF Sevrioukova International Journal of Molecular Sciences 23 (13), 7291, 2022 | 3 | 2022 |
| Measuring Erosion of Biodegradable Polymers in Brimonidine Drug Delivery Implants by Quantitative Proton NMR Spectroscopy (q-HNMR) H Wang, M Roof, K Burgher, C Pham, ER Samuels, Y He, H Jian, T Wang Journal of Pharmaceutical Sciences, 2024 | | 2024 |
| Novel CYP3A4-Specific Inhibitors and Methods of Using Same IF Sevrioukova, ER Samuels US Patent App. 18/258,610, 2024 | | 2024 |
| Simultaneous relative UV response determination of known liquid drug product degradants by NMR spectroscopy ER Samuels, T Wang Journal of Pharmaceutical and Biomedical Analysis 213 (114665), 2022 | | 2022 |
| A Tale of Two Cities: Merging Biology with Chemistry for Drug Design ER Samuels University of California, Irvine, 2018 | | 2018 |
