| Baseline quasispecies selection and novel mutations contribute to emerging resistance-associated substitutions in hepatitis C virus after direct-acting antiviral treatment Y Kai, H Hikita, N Morishita, K Murai, T Nakabori, S Iio, H Hagiwara, ... Scientific reports 7 (1), 41660, 2017 | 32 | 2017 |
| Sodium taurocholate cotransporting polypeptide inhibition efficiently blocks hepatitis B virus spread in mice with a humanized liver T Nakabori, H Hikita, K Murai, Y Nozaki, Y Kai, Y Makino, Y Saito, ... Scientific reports 6 (1), 27782, 2016 | 26 | 2016 |
| Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non–Cell Autonomous Liver Carcinogenesis Y Makino, H Hikita, K Fukumoto, JH Sung, Y Sakano, K Murai, S Sakane, ... Cancer Research 82 (16), 2860-2873, 2022 | 23 | 2022 |
| Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation T Tamura, T Kodama, K Sato, K Murai, T Yoshioka, M Shigekawa, ... The Journal of Clinical Investigation 131 (13), 2021 | 19 | 2021 |
| Hepatitis C virus infection suppresses hepatitis B virus replication via the RIG-I-like helicase pathway K Murai, H Hikita, Y Kai, Y Kondo, M Fukuoka, K Fukutomi, A Doi, T Yamai, ... Scientific Reports 10 (1), 941, 2020 | 19 | 2020 |
| Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels K Sato, H Hikita, Y Myojin, K Fukumoto, K Murai, S Sakane, T Tamura, ... PloS one 15 (7), e0235573, 2020 | 18 | 2020 |
| TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation Y Shiode, T Kodama, S Shigeno, K Murai, S Tanaka, JY Newberg, ... Hepatology 77 (2), 395-410, 2023 | 10 | 2023 |
| SIRT1 enhances hepatitis virus B transcription independent of hepatic autophagy T Yamai, H Hikita, M Fukuoka, K Fukutomi, K Murai, T Nakabori, ... Biochemical and Biophysical Research Communications 527 (1), 64-70, 2020 | 10 | 2020 |
| Metastatic colon neuroendocrine carcinoma found in a patient with ulcerative colitis during annual endoscopic surveillance T Yoshihara, S Shinzaki, S Hiyama, K Murai, T Takehara Gastrointestinal Endoscopy 84 (6), 1075-1076, 2016 | 8 | 2016 |
| STAT3 is Activated by CTGF-mediated Tumor-stroma Cross Talk to Promote HCC Progression Y Makino, H Hikita, S Kato, M Sugiyama, M Shigekawa, T Sakamoto, ... Cellular and Molecular Gastroenterology and Hepatology 15 (1), 99-119, 2023 | 7 | 2023 |
| Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus–Infected Hepatocytes During Interferon Administration K Fukutomi, H Hikita, K Murai, T Nakabori, A Shimoda, M Fukuoka, ... Hepatology Communications 6 (2), 281-296, 2022 | 6 | 2022 |
| HepaSH cells: Experimental human hepatocytes with lesser inter-individual variation and more sustainable availability than primary human hepatocytes S Uehara, Y Higuchi, N Yoneda, R Ito, T Takahashi, N Murayama, ... Biochemical and Biophysical Research Communications 663, 132-141, 2023 | 5 | 2023 |
| Inhibition of nonhomologous end joining‐mediated DNA repair enhances anti‐HBV CRISPR therapy K Murai, T Kodama, H Hikita, A Shimoda, M Fukuoka, K Fukutomi, ... Hepatology Communications 6 (9), 2474-2487, 2022 | 5 | 2022 |
| Gab1 in livers with persistent hepatocyte apoptosis has an antiapoptotic effect and reduces chronic liver injury, fibrosis, and tumorigenesis N Mizutani, H Hikita, Y Saito, Y Myojin, K Sato, M Urabe, T Kurahashi, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 320 (6 …, 2021 | 5 | 2021 |
| Pentraxin 3 is an adipose tissue‐related serum marker for pancreatic cancer cachexia predicting subsequent muscle mass and visceral fat loss K Sato, H Hikita, M Shigekawa, S Kato, Y Sasaki, K Shinkai, M Fukuoka, ... Cancer Science 113 (12), 4311-4326, 2022 | 4 | 2022 |
| Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver … Y Nozaki, H Hikita, S Tanaka, K Fukumoto, M Urabe, K Sato, Y Myojin, ... Scientific Reports 11 (1), 3363, 2021 | 4 | 2021 |
| The impact of the COVID‐19 pandemic on hepatocellular carcinoma diagnosis and treatment in Japan: A multicenter collaborative observational study K Murai, H Hikita, T Kodama, M Kaibori, Y Nishimura, T Tatsumi, ... Hepatology Research, 2023 | 2 | 2023 |
| Fucosylated haptoglobin is a novel predictive marker of hepatocellular carcinoma after hepatitis C virus elimination in patients with advanced liver fibrosis K Shirai, H Hikita, R Sakamori, A Doi, Y Tahata, S Sakane, Y Kamada, ... Plos one 17 (12), e0279416, 2022 | 1 | 2022 |
| The first case of coil embolization for left gastric vein aneurysm with liver cirrhosis: a case report and review of the literature S Kato, R Sakamori, R Yamada, K Murai, T Yoshioka, Y Tahata, ... Internal Medicine 60 (16), 2617-2622, 2021 | 1 | 2021 |
| HBV/HCV 共感染患者に対する DAA 治療後の HBV 再活性化 村井一裕， 疋田隼人， 竹原徹郎 肝臓 61 (5), 240-241, 2020 | 1 | 2020 |
Ryotaro SakamoriOsaka University Graduate School of MedicineVerified email at gh.med.osaka-u.ac.jp
