| Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates B Ozgür, L Saaby, K Langthaler, B Brodin European Journal of Pharmaceutical Sciences 112, 112-121, 2018 | 8 | 2018 |
| Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells SSE Nielsen, MR Holst, K Langthaler, SC Christensen, EH Bruun, ... Fluids and Barriers of the CNS 20 (1), 2, 2023 | 6 | 2023 |
| Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain … B Ozgür, L Saaby, C Janfelt, K Langthaler, E Eneberg, AM Jacobsen, ... European Journal of Pharmaceutics and Biopharmaceutics 169, 211-219, 2021 | 6 | 2021 |
| Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates B Ozgür, L Saaby, K Langthaler, B Brodin Data in brief 16, 655-659, 2018 | 6 | 2018 |
| Assessing extent of brain penetration in vivo (Kp, uu, brain) in Göttingen minipig using a diverse set of reference drugs K Langthaler, CR Jones, B Brodin, C Bundgaard European Journal of Pharmaceutical Sciences 190, 106554, 2023 | 5 | 2023 |
| Characterisation of intravenous pharmacokinetics in Göttingen minipig and clearance prediction using established in vitro to in vivo extrapolation methodologies K Langthaler, CR Jones, RB Christensen, E Eneberg, B Brodin, ... Xenobiotica 52 (6), 591-607, 2022 | 5 | 2022 |
| Practical Application of Rodent Transporter Knockout Models to Assess Brain Penetration in Drug Discovery E Eneberg, CR Jones, T Jensen, K Langthaler, C Bundgaard Drug Metabolism and Bioanalysis Letters Formerly: Drug Metabolism Letters 15 …, 2022 | 3 | 2022 |
| Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution K Langthaler, CR Jones, L Saaby, C Bundgaard, B Brodin Fluids and Barriers of the CNS 21 (1), 11, 2024 | | 2024 |
